A note on the calculation of intrasubject coefficient of variation in bioequivalence Trails

Journal of Bioanalysis and Biomedicine

Volumn 2, Issue 4, 2010, Pages 75-78

  Mohsen, Mahmoud Abdel ^a  

^a ROYAL SCIENTIFIC SOCIETY   (Jordan)

Author keywords

Bioequivalence; Coefficient of variation; Crossover design; Normal and log normal distribution; Sample size

Indexed keywords

ERYTHROMYCIN; ERYTHROMYCIN STEARATE;

ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD SAMPLING; CALCULATION; CLINICAL TRIAL (TOPIC); COEFFICIENT OF VARIATION; CONSTANTS AND COEFFICIENTS; CORRELATION COEFFICIENT; DRUG ABSORPTION; DRUG BIOAVAILABILITY; HUMAN; INTRARATER RELIABILITY; MATHEMATICAL MODEL; MAXIMUM PLASMA CONCENTRATION; NORMAL DISTRIBUTION; PLASMA CONCENTRATION-TIME CURVE; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; STUDY DESIGN; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

EID: 79952604044     PISSN: None     EISSN: 1948593X     Source Type: Journal    
DOI: 10.4172/1948-593X.1000026     Document Type: Article

References (3)

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3. Schuirmann DJ (1987) A Comparison of the two one-sided tests procedures and the power approach for assessing the equivalence of average bioavailability. J Pharmacokinet Biopharm 15: 657-680.