Focal splenic lesions in type I Gaucher disease are associated with poor platelet and splenic response to macrophage-targeted enzyme replacement therapy

Journal of Inherited Metabolic Disease

Volumn 33, Issue 6, 2010, Pages 769-774

  Stein, Philip ^a   Pastores, Gregory M ^b   Malhotra, Advitya ^c   Haims, Andrew ^a   Mistry, Pramod K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; AVASCULAR NECROSIS; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME REPLACEMENT; FEMALE; GAUCHER DISEASE; GAUCHER DISEASE TYPE 1; HUMAN; HUMAN TISSUE; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; SPLEEN INJURY; SPLENOMEGALY; THROMBOCYTE COUNT; THROMBOCYTOPENIA; BLOOD; DRUG DELIVERY SYSTEM; DRUG EFFECT; EVALUATION; FOLLOW UP; METHODOLOGY; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; SPLEEN; SPLEEN DISEASE; THROMBOCYTE DISORDER; TREATMENT FAILURE;

GLUCOSYLCERAMIDASE;

ADULT; BLOOD PLATELET DISORDERS; DRUG DELIVERY SYSTEMS; ENZYME REPLACEMENT THERAPY; FEMALE; FOLLOW-UP STUDIES; GAUCHER DISEASE; GLUCOSYLCERAMIDASE; HUMANS; MACROPHAGES; MALE; PLATELET COUNT; PROGNOSIS; RETROSPECTIVE STUDIES; SPLEEN; SPLENIC DISEASES; TREATMENT FAILURE;

EID: 79952602089     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-010-9175-6     Document Type: Article

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