Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 7, 2011, Pages 2717-2722

  Belousoff, Matthew J ^a   Shapira, Tal ^a   Bashan, Anat ^a   Zimmerman, Ella ^a   Rozenberg, Haim ^a   Arakawa, Kenji ^b   Kinashi, Haruyasu ^b   Yonath, Ada ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Protein exit tunnel; Ribosomes

Indexed keywords

ANTIBIOTIC AGENT; DALFOPRISTIN; ERYTHROMYCIN; LANKACIDIN C; LANKAMYCIN; MIKAMYCIN B; PEPTIDYLTRANSFERASE; RNA 23S; UNCLASSIFIED DRUG;

ARTICLE; CELL FUNCTION; CRYSTAL STRUCTURE; DEINOCOCCUS RADIODURANS; DRUG BINDING SITE; DRUG POTENTIATION; DRUG STRUCTURE; PRIORITY JOURNAL; RIBOSOME SUBUNIT;

ANTI-BACTERIAL AGENTS; BINDING SITES; CRYSTALLOGRAPHY; DNA FOOTPRINTING; DRUG SYNERGISM; ERYTHROMYCIN; INHIBITORY CONCENTRATION 50; MACROLIDES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RIBOSOME SUBUNITS, LARGE; RNA, RIBOSOMAL, 23S; X-RAY DIFFRACTION;

DEINOCOCCUS RADIODURANS;

EID: 79952598516     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1019406108     Document Type: Article

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