Biosynthetic corneas: Prospects for supplementing the human donor cornea supply

Expert Review of Medical Devices

Volumn 8, Issue 2, 2011, Pages 127-130

  Lagali, Neil ^a   Fagerholm, Per ^a   Griffith, May ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

Author keywords

biosynthetic cornea; corneal regeneration; corneal transplantation; donor cornea; keratoplasty

Indexed keywords

BIOMATERIAL;

BIOSYNTHETIC CORNEA; CORNEA CELL; CORNEA TRANSPLANTATION; HUMAN; KERATOCONUS; KERATOPLASTY; KERATOPROSTHESIS; ORGAN DONOR; REGENERATION; REVIEW;

BIOARTIFICIAL ORGANS; CLINICAL TRIALS AS TOPIC; CORNEA; GUIDED TISSUE REGENERATION; HUMANS; PROSTHESES AND IMPLANTS; TISSUE DONORS;

EID: 79952591357     PISSN: 17434440     EISSN: 17452422     Source Type: Journal    
DOI: 10.1586/erd.10.89     Document Type: Review

References (24)

1. Whitcher JP, Srinivasan M, Upadhyay MP. Corneal blindness: a global perspective Bull. World Health Organ. 79, 214-221 (2001).
2. Griffith M, Jackson WB, Lagali N, Merrett K, Li F, Fagerholm P. Artificial corneas: a regenerative medicine approach. Eye 23, 1985-1989 (2009).
3. Fagerholm P, Lagali N, Carlsson D, Merrett K, Griffith M. Corneal regeneration following implantation of a biomimetic tissue-engineered substitute. Clin. Transl. Sci. 2, 162-164 (2009).
4. Fagerholm P, Lagali NS, Merrett K et al. A biosynthetic alternative to human donor tissue for inducing corneal regeneration: 24 month follow-up of a Phase I clinical study. Sci. Transl. Med. 2, 46ra61 (2010).
5. Remeijer L, Maertzdorf J, Doornenbal P, Verjans GM, Osterhaus AD. Herpes simplex virus 1 transmission through corneal transplantation. Lancet 357, 442 (2001). (Pubitemid 32156146)
6. Hassan SS, Wilhemus KR, Dahl P et al. Infectious disease risk factors of corneal donor grafts. Arch. Ophthalmol. 126, 235-239 (2008). (Pubitemid 351240853)
7. Moffatt SL, Cartwright VA, Stumpf TH. Centennial review of corneal transplantation. Clin. Exp. Ophthalmol. 33, 642-657 (2005).
8. Mamalis N, Anderson CW, Kreisler KR et al. Changing trends in the indications for penetrating keratoplasty. Arch. Ophthalmol. 110, 1409-1411 (1992).
9. Ardjomand N, Hau S, McAlister JC et al. Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts. Am. J. Ophthalmol. 143, 228-235 (2007).
10. Li F, Carlsson D, Lohmann C et al. Cellular and nerve regeneration within a biosynthetic extracellular matrix for corneal transplantation. Proc. Natl Acad. Sci. USA 100, 15346-15351 (2003). (Pubitemid 38020992)
11. Liu Y, Gan L, Carlsson DJ et al. A simple, cross-linked collagen tissue substitute for corneal implantation. Invest. Ophthalmol. Vis. Sci. 47, 1869-1875 (2006). (Pubitemid 46768266)
12. Merrett K, Fagerholm P, Tsai RJF et al. Tissue engineered recombinant human collagen-based corneal substitutes for implantation: performance of type I vs type III collagen. Invest. Ophthalmol. Vis. Sci. 49, 3887-3894 (2008).
13. Liu W, Deng C, McLaughlin CR et al. Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes. Biomaterials 30, 1551-1559 (2009).
14. Hackett J, Lagali N, Merrett K et al. Biosynthetic corneal implants for replacement of pathologic corneal tissue: performance in a controlled rabbit alkali burn model. Invest. Ophthalmol. Vis. Sci. 52, 651-657 (2011).
15. McLaughlin CR, Acosta MC, Luna C et al. Regeneration of functional nerves within full thickness collagen-phosphorylcholine corneal substitute implants in guinea pigs. Biomaterials 31, 2770-2778 (2010).
16. Koizumi N, Sakamoto Y, Okumura N et al. Cultivated corneal endothelial cell sheet transplantation in a primate model. Invest. Ophthalmol. Vis. Sci. 48, 4519-4526 (2007). (Pubitemid 351260967)
17. Liu L, Kuffová L, Griffith M et al. Immunological responses in mice to full-thickness corneal grafts engineered from porcine collagen. Biomaterials 28, 3807-3814 (2007). (Pubitemid 47048349)
18. Lagali N, Griffith M, Fagerholm P et al. Innervation of tissue-engineered recombinant human collagen-based corneal substitutes: a comparative in vivo confocal microscopy study. Invest. Ophthalmol. Vis. Sci. 49, 3895-3902 (2008).
19. Niederer RL, Perumal D, Sherwin T, McGhee CNJ. Corneal innervation and cellular changes after corneal transplantation: an in vivo confocal microscopy study. Invest. Ophthalmol. Vis. Sci. 48, 621-626 (2007). (Pubitemid 351260693)
20. Rao GN, John T, Ishida N, Aquavella JV. Recovery of corneal sensitivity in grafts following penetrating keratoplasty. Ophthalmology 92, 1408-1411 (1985). (Pubitemid 16228033)
21. Tervo T, Vannas A, Tervo K, Holden BA. Histochemical evidence of limited reinnervation of human corneal grafts. Acta. Ophthalmol. 63, 207-214 (1985). (Pubitemid 15083595)
22. Escapini H. Nerve changes in the human corneal graft. AMA Arch. Ophthalmol. 53, 229-235 (1955).
23. Wollensak G, Green WR. Analysis of sex-mismatched human corneal transplants by fluorescence in situ hybridization of the sex-chromosomes. Exp. Eye Res. 68, 341-346 (1999). (Pubitemid 29130723)
24. Lagali N, Stenevi U, Claesson M, Fagerholm P, Hanson C, Weijdegård B; Swedish Society of Corneal Surgeons. Survival of donor-derived cells after human corneal transplantation. Invest. Ophthalmol. Vis. Sci. 50, 2673-2678 (2009).