Thrombin generation in patients with acquired haemophilia and clinical bleeding risk

British Journal of Haematology

Volumn 153, Issue 1, 2011, Pages 136-139

  Millet, Arnaud ^a,b   Graveleau, Julie ^c   Gueret, Pierre ^a   Trossaërt, Marc ^c   Decaux, Olivier ^a   Aouba, Achille ^d   Lasne, Dominique ^d   Guillet, Benoît ^a,e  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^b SERVICE DE RHUMATOLOGIE   (France)

^c HÔTEL DIEU   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Acquired haemophilia; Bleeding phenotype; Factor VIII; Thrombin generation assay

Indexed keywords

BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 8 INHIBITOR; THROMBIN; THROMBOPLASTIN;

ADULT; BLEEDING TENDENCY; BLOOD CLOTTING TEST; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; HEMOPHILIA A; HUMAN; LETTER; PARTIAL THROMBOPLASTIN TIME; PATIENT CODING; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REMISSION; THROMBIN TIME; THROMBOCYTE POOR PLASMA;

ADOLESCENT; ADULT; AGED; HEMOPHILIA A; HEMORRHAGE; HUMANS; MIDDLE AGED; RETROSPECTIVE STUDIES; RISK ASSESSMENT; THROMBIN; YOUNG ADULT;

EID: 79952581641     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08517.x     Document Type: Letter

References (10)

1. Al Dieri, R., Peyvandi, F., Santagostino, E., Giansily, M., Mannucci, P.M., Schved, J.F., Beguin, S. & Hemker, H.C. (2002) The thrombogram in rare inherited coagulation disorders: its relation to clinical bleeding. Thrombosis and Haemostasis, 88, 576-582.
2. Brummel, K.E., Paradis, S.G., Butenas, S. & Mann, K.G. (2002) Thrombin functions during tissue factor-induced blood coagulation. Blood, 100, 148-152.
3. Collins, P.W., Hirsch, S., Baglin, T.P., Dolan, G., Hanley, J., Makris, M., Keeling, D.M., Liesner, R., Brown, S.A. & Hay, C.R. (2007) Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation. Blood, 109, 1870-1877.
4. Dargaud, Y., Beguin, S., Lienhart, A., Al Dieri, R., Trzeciak, C., Bordet, J.C., Hemker, H.C. & Negrier, C. (2005) Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B. Thrombosis and Haemostasis, 93, 475-480.
5. Delgado, J., Jimenez-Yuste, V., Hernandez-Navarro, F. & Villar, A. (2003) Acquired haemophilia: review and meta-analysis focused on therapy and prognostic factors. British Journal of Haematology, 121, 21-35.
6. Hemker, H.C., Giesen, P., Al Dieri, R., Regnault, V., de Smedt, E., Wagenvoord, R., Lecompte, T. & Beguin, S. (2003) Calibrated automated thrombin generation measurement in clotting plasma. Pathophysiology, Haemostasis and Thrombosis, 33, 4-15.
7. Huth-Kuhne, A., Baudo, F., Collins, P., Ingerslev, J., Kessler, C.M., Levesque, H., Castellano, M.E., Shima, M. & St-Louis, J. (2009) International recommendations on the diagnosis and treatment of patients with acquired hemophilia A. Haematologica, 94, 566-575.
8. Levesque, H., Tengborg, L., Marco, P., Baudo, F., Collins, P., Knobl, P., Huth-Kuhne, A. & Nemes, L.. (2009) Acquired haemophilia: descriptive data of the European acquired haemophila registry (EACH2). Journal of Thrombosis and Haemostasis, 7, Abstr We 604.
9. Schulman, S. & Kearon, C.; Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. (2005) Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. Journal of Thrombosis and Haemostasis, 3, 692-694.
10. van Veen, J.J., Gatt, A., Bowyer, A.E., Cooper, P.C., Kitchen, S. & Makris, M. (2009) Calibrated automated thrombin generation and modified thromboelastometry in haemophilia A. Thrombosis Research, 123, 895-901.