Serum antibody kinetics following nasal or parenteral challenge with meningococcal polysaccharide in healthy adults

Clinical and Vaccine Immunology

Volumn 18, Issue 3, 2011, Pages 424-429

  Findlow, H ^a   Borrow, R ^a   Hardelid, P ^a   Newton, E ^a   Frankland, S ^a   Naylor, S ^b   Miller, E ^a   Kaczmarski, E ^a   Read, R C ^b  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN G; MENGIVAC; MENINGOCOCCAL SEROGROUP A C POLYSACCHARIDE VACCINE; MENINGOCOCCAL SEROGROUP C CONJUGATE VACCINE; MENINGOCOCCUS VACCINE; POLYSACCHARIDE VACCINE; UNCLASSIFIED DRUG;

ACTIVE IMMUNIZATION; ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; IMMUNOGENICITY; IMMUNOLOGICAL MEMORY; INFECTION PREVENTION; MALE; MENINGOCOCCOSIS; MUCOSAL IMMUNITY; NORMAL HUMAN; NOSE PROVOCATION TEST; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SERUM BACTERICIDAL ANTIBODY ASSAY;

ADMINISTRATION, INTRANASAL; ADULT; ANTIBODIES, BACTERIAL; BLOOD BACTERICIDAL ACTIVITY; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; INJECTIONS, INTRAVENOUS; MALE; MENINGOCOCCAL VACCINES; NEISSERIA MENINGITIDIS, SEROGROUP C; POLYSACCHARIDES, BACTERIAL; TIME FACTORS;

EID: 79952550590     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00503-10     Document Type: Article

References (25)

1. Andrews, N., R. Borrow, and E. Miller. 2003. Validation of serological correlate of protection for meningococcal C conjugate vaccine by using efficacy estimates from postlicensure surveillance in England. Clin. Diagn. Lab Immunol. 10:780-786.
2. Auckland, C., et al. 2006. Clinical and immunologic risk factors for meningococcal C conjugate vaccine failure in the United Kingdom. J. Infect. Dis. 194:1745-1752.
3. Borrow, R., et al. 2001. Comparison of antibody kinetics following meningococcal serogroup C conjugate vaccine between healthy adults previously vaccinated with meningococcal A/C polysaccharide vaccine and vaccine-naïve controls. Vaccine 19:3043-3050. (Pubitemid 32324031)
4. Borrow, R., et al. 2002. Antibody persistence and immunological memory at age 4 years after meningococcal group C conjugate vaccination in children in the United Kingdom. J. Infect. Dis. 186:1353-1357.
5. Carlone, G. M., et al. 1992. Multicenter comparison of levels of antibody to the Neisseria meningitidis group A capsular polysaccharide measured by using an enzyme-linked immunosorbent assay. J. Clin. Microbiol. 30:154-159.
6. Choo, S., et al. 2000. Immunogenicity and reactogenicity of a group C meningococcal conjugate vaccine compared with a group A+C meningococcal polysaccharide vaccine in adolescents in a randomised observer-blind controlled trial. Vaccine 18:2686-2692. (Pubitemid 30211576)
7. de Voer, R. M., et al. 2009. Kinetics of antibody responses after primary immunization with meningococcal serogroup C conjugate vaccine or secondary immunization with either conjugate or polysaccharide vaccine in adults. Vaccine 27:6974-6982.
8. Goldschneider, I., E. C. Gotschlich, and M. S. Artenstein. 1969. Human immunity to the meningococcus. II. Development of natural immunity. J. Exp. Med. 129:1327-1348.
9. Holder, P. K., S. E. Maslanka, L. B. Pais, J. Dykes, B. D. Plikaytis, and G. M. Carlone. 1995. Assignment of Neisseria meningitidis serogroup A and C class-specific anticapsular antibody concentrations to the new standard reference serum CDC1992. Clin. Diag. Lab. Immunol. 2:132-137.
10. Kauppi, M., J. Eskola, and H. Käyhty. 1995. Anti-capsular polysaccharide antibody concentrations in saliva after immunization with Haemophilus influenzae type b conjugate vaccines. Pediatr. Infect. Dis. J. 14:286-294.
11. Maiden, M. C., J. M. Stuart, and U. K. Meningococcal Carriage Group. 2002. Carriage of serogroup C meningococci 1 year after meningococcal C conjugate polysaccharide vaccination. Lancet 359:1829-1831.
12. Maiden, M. C., et al. 2008. Impact of meningococcal serogroup C conjugate vaccines on carriage and herd immunity. J. Infect. Dis. 197:737-743.
13. Maslanka, S. E., et al. 1997. Standardisation and a multilaboratory comparison of Neisseria meningitidis group A and C serum bactericidal assays. Clin. Diagn. Lab. Immunol. 4:156-167.
14. Miller, E., D. Salisbury, and M. Ramsay. 2001. Planning, registration, and implementation of an immunisation campaign against meningococcal serogroup C disease in the UK: a success story. Vaccine 20:S58-S67. (Pubitemid 32925012)
15. Nurkka, A., et al. 2000. Salivary antibody response to vaccination with meningococcal A/C polysaccharide vaccine in previously vaccinated and unvaccinated Gambian children. Vaccine 19:547-556.
16. Pollard, A. J., K. P. Perrett, and P. C. Beverley. 2009. Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines. Nat. Rev. Immunol. 9:213-220.
17. Ramsay, M. E., N. Andrews, C. L. Trotter, E. B. Kaczmarski, and E. Miller. 2003. Herd immunity from meningococcal serogroup C conjugate vaccination in England: database analysis. BMJ 326:365-366. (Pubitemid 36241472)
18. Richmond, P., et al. 1999. Meningococcal serogroup C conjugate vaccine is immunogenic in infancy and primes for memory. J. Infect. Dis. 179:1569-1572.
19. Richmond, P., et al. 2001. Ability of 3 different meningococcal C conjugate vaccines to induce immunologic memory after a single dose in UK toddlers. J. Infect. Dis. 183:160-163.
20. Snape, M. D., et al. 2006. Serogroup C meningococcal glycoconjugate vaccine in adolescents: persistence of bactericidal antibodies and kinetics of the immune response to a booster vaccine more than 3 years after immunization. Clin. Infect. Dis. 43:1387-1394.
21. Tsai, T. F., et al. 2006. Early appearance of bactericidal antibodies after polysaccharide challenge of toddlers primed with a group C meningococcal conjugate vaccine: what is its role in the maintenance of protection? Clin. Vaccine Immunol. 13:854-861. (Pubitemid 44409623)
22. Zangwill, K. M., et al. 1994. Duration of antibody response after meningococcal polysaccharide vaccination in US Air Force personnel. J. Infect. Dis. 169:847-852.
23. Zhang, Q., S. Choo, J. Everard, R. Jennings, and A. Finn. 2000. Mucosal immune responses to meningococcal group C conjugate and group A and C polysaccharide vaccines in adolescents. Infect. Immun. 68:2692-2697.
24. Zhang, Q., et al. 2001. Primary and booster mucosal immune responses to meningococcal group A and C conjugate and polysaccharide vaccines administered to University students in the United Kingdom. Infect. Immun. 69:4337-4341.
25. Zhang, Q., et al. 2002. Mucosal immune responses to meningococcal conjugate polysaccharide vaccines in infants. Pediatr. Infect. Dis. J. 21:209-213.