Secondary electrospray ionization-mass spectrometry: Breath study on a control group

Journal of Breath Research

Volumn 5, Issue 1, 2011, Pages

  Martinez Lozano P ^a   Zingaro, L ^b   Finiguerra, A ^b   Cristoni, S ^a,b  

^a CNR   (Italy)

^b ISB Ion Source and Biotechnologies   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; FATTY ACID DERIVATIVE; HEXANOIC ACID; PROPIONIC ACID; SUCROSE; VALERIC ACID; VOLATILE ORGANIC COMPOUND; HEXANOIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE; VALERIC ACID DERIVATIVE;

ALGORITHM; ARTICLE; BREATH ANALYSIS; CONCENTRATION (PARAMETERS); DIET RESTRICTION; ELECTROSPRAY MASS SPECTROMETRY; FATTY ACID BLOOD LEVEL; HUMAN; MOUTH BREATHING; NOSE BREATHING; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SCORING SYSTEM; SECONDARY ELECTROSPRAY IONIZATION MASS SPECTROMETRY; SENSITIVITY AND SPECIFICITY; SUGAR INTAKE; VAPOR; EXHALATION; METABOLISM; METHODOLOGY;

BREATH TESTS; BUTYRIC ACID; EXHALATION; FASTING; HEXANOIC ACIDS; HUMANS; PENTANOIC ACIDS; PROPIONIC ACIDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUCROSE;

EID: 79952550444     PISSN: 17527155     EISSN: 17527163     Source Type: Journal    
DOI: 10.1088/1752-7155/5/1/016002     Document Type: Article

References (44)

1. Szulejko J E, McCulloch M, Jackson J, McKee D L, Walker J C and Solouki T 2010 Evidence for cancer biomarkers in exhaled breath IEEE Sensors J. 10 185-210
2. Lovett A M, Reid N M, Buckley J A, French J B and Cameron D M 1979 Real-time analysis of breath using an atmospheric pressure ionization mass spectrometer Biomed. Mass Spectrom. 6 91-7 (Pubitemid 9147100)
3. Benoit F M, Davidson W R, Lovett A M, Nacson S and Ngo A 1983 Breath analysis by atmospheric pressure ionization mass spectrometry Anal. Chem. 55 805-7
4. Lindinger W, Hansel A and Jordan A 1998 On-line monitoring of volatile organic compounds at pptv levels by means of proton-transfer-reaction mass spectrometry (PTR-MS) medical applications, food control and environmental research Int. J. Mass Spectrom. Ion Process. 173 191-241
5. Smith D and Španěl P 2005 Selected ion flow tube mass spectrometry (SIFT-MS) for on-line trace gas analysis Mass Spectrom. Rev. 24 661-700 (Pubitemid 41615714)
6. Herbig J, Müller M, Schallhart S and Titzmann T 2009 On-line breath analysis with PTR-TOF J. Breath Res. 3 027004
7. Martínez-Lozano P and Fernández de la Mora J 2008 Direct analysis of fatty acid vapors in breath by electrospray ionization and atmospheric pressure ionization mass spectrometry Anal. Chem. 80 8210
8. Whitehouse C M, Levin F, Meng C K and Fenn J B 1986 34th ASMS Conf. on Mass Spectrom. and Allied Topics (Cincinnati, OH) p 507
9. Fuerstenau S 1994 Aggregation and fragmentation in an electrospray ion source PhD Thesis Yale University
10. Fuerstenau S, Kiselev P and Fenn J B 1999 ESIMS in the analysis of trace species in gases 47th ASMS Conf. on Mass Spectrometry (Dallas, TX, June 1999)
11. Chen Y H, Hill H H and Wittmer D P 1994 Analytical merit of electrospray ion mobility spectrometry as a chromatographic detector J. Microcolumn Separations 6 515
12. Wu C, Siems W F and Hill H H 2000 Secondary electrospray ionization ion mobility spectrometry - mass spectrometry of illicit drugs Anal. Chem. 72 396
13. Lee C Y and Shiea J 1998 Gas chromatography connected to multiple channel electrospray ionization mass spectrometry for the detection of volatile organic compounds Anal. Chem. 70 2757-61
14. Chen H, Wortmann A, Zhang W and Zenobi R 2007 Rapid in vivo fingerprinting of nonvolatile compounds in breath by extractive electrospray ionization quadrupole time-of-flight mass spectrometry Angew. Chem. Int. Ed. 46 580-3 (Pubitemid 46159202)
15. Martínez-Lozano P and Fernández de la Mora J 2007 Electrospray ionization of volatiles in breath Int. J. Mass Spectrom. 265 68
16. Fernández de la Mora J 2010 Ionization of vapor molecules by an electrospray cloud Int. J. Mass Spectrom. doi:10.1016/j.ijms.2010.09.009
17. Kiselev P and Fenn J B 2001 ESIMS analysis of vapors at trace levels Proc. 49th ASMS Conf. on Mass Spectrometry and Allied Topics (Chicago, IL, May 2001)
18. Martinez-Lozano P, Rus J, Fernández de la Mora G, Hernández M and Fernández de la Mora J 2009 Secondary electrospray ionization (SESI) of ambient vapors for explosive detection at concentrations below parts per trillion J. Am. Soc. Mass Spectrom. 20 287
19. Dillon L A, Stone V N, Croasdell L A, Fielden P R, Goddard N J and Thomas C L 2010 Optimisation of secondary electrospray ionisation (SESI) for the trace determination of gas-phase volatile organic compounds Analyst 135 306-14
20. Reynolds J C et al 2010 Detection of volatile organic compounds in breath using thermal desorption electrospray ionization-ion mobility-mass spectrometry Anal. Chem. 82 2139-44
21. O'Hara M E, Clutton-Brock T H, Green S and Mayhew C A 2009 Endogenous volatile organic compounds in breath and blood of healthy volunteers: examining breath analysis as a surrogate for blood measurements J. Breath Res. 3 027005
22. Anderson J C, Babb A L and Hlastala M P 2003 Modeling soluble gas exchange in the airways and alveoli Ann. Biomed. Eng. 31 1402-22
23. Staudinger J and Roberts P V 1996 A critical review of Henry's law constants for environmental applications Crit. Rev. Environ. Sci. Technol. 26 205-97
24. Yaws H C and Yang C L 1992 Henry's Law Constant for Compound in Water (Houston, TX: Company Gulf Publishing) pp 181-206
25. Mesonero E, Sillero J A, Hernández M and Fernández de la Mora J 2009 Secondary electrospray ionization detection of explosive vapors below 0.02 ppt on a triple quadrupole with an atmospheric pressure source 57th ASMS Conf. on Mass Spectrometry and Allied Topics (Philadelphia, PA) p 314
26. Cummings J H 1983 Fermentation in the human large intestine: evidence and implications for health Lancet 321 1206-9 (Pubitemid 13092719)
27. Li M et al 2008 Symbiotic gut microbes modulate human metabolic phenotypes Proc. Natl Acad. Sci. USA 105 2117-22 (Pubitemid 351439474)
28. Gorbach S L, Mayhew J W, Bartlett J G, Thadepalli H and Onderdonk A B 1976 Rapid diagnosis of anaerobic infections by direct gas liquid chromatography of clinical specimens J. Clin. Invest. 57 478-84
29. Kurita-Ochiai T, Fukushima K and Ochiai K 1995 Volatile fatty acids, metabolic by-products of periodontopathic bacteria, inhibit lymphocyte proliferation and cytokine production J. Dent. Res. 74 1367-73
30. Tangerman A and Winkel E G 2007 Intra- and extra-oral halitosis: finding of a new form of extra-oral blood-borne halitosis caused by dimethyl sulphide J. Clin. Periodontol. 34 748-55
31. Wang T, Pysanenko A, Dryahina K, Španěl P and Smith D 2008 Analysis of breath, exhaled via the mouth and nose, and the air in the oral cavity J. Breath Res. 2 037013
32. Metz G, Drasar B S, Gassull M A, Jenkins D J and Blendis L M 1976 Breath-hydrogen test for small-intestinal bacterial colonisation Lancet 307 (7961) 668-9
33. Saad R J and Chey W D 2007 Breath tests for gastrointestinal disease: the real deal or just a lot of hot air? Gastroenterologica 133 1763-6 (Pubitemid 350180840)
34. Clausen M R, Mortensen P B and Bendtsen F 1991 Serum levels of short-chain fatty acids in cirrhosis and hepatic coma Hepatology 14 1040-5
35. Chen S, Mahadevan V and Zieve L 1970 Volatile fatty acids in the breath of patients with cirrhosis of the liver J. Lab. Clin. Med. 75 622-7
36. Bernini P, Bertini I, Luchinat C, Nepi S, Saccenti E, Schäfer H, Schütz B, Spraul M and Tenori L 2009 Individual human phenotypes in metabolic space and time J. Proteome. Res. 8 4264-71
37. Assfalg M, Bertini I, Colangiuli D, Luchinat C, Schäfer H, Schütz B and Spraul M 2008 Evidence of different metabolic phenotypes in humans Proc. Natl Acad. Sci. USA 105 1420-4 (Pubitemid 351346527)
38. Martínez-Lozano P and Fernández de la Mora J 2009 On-line detection of human skin vapors J. Am. Soc. Mass Spectrom. 20 1060-63
39. Grice E A et al 2009 Topographical and temporal diversity of the human skin microbiome Science 324 1190-2
40. Stein S 1994 Estimating probabilities of correct identification from results of mass spectral library searches J. Am. Soc. Mass Spectrom. 5 316-23
41. Cristoni S et al 2009 MALDI-MS-NIST library approach for colorectal cancer diagnosis Rapid Commun. Mass Spectrom. 23 2839-45
42. Khan I, Brimblecombe P and Clegg S L 1995 Solubilities of pyruvic acid and the lower (C1-C6) carboxylic acids. Experimental determination of equilibrium vapour pressures above pure aqueous and salt solutions J. Atmos. Chem. 22 285-302 (Pubitemid 26444816)
43. Servant J, Kouadio J, Cros B and Delmas R 1991 Carboxylic monoacids in the air of Mayombe Forest (Congo): role of the forest as a source or sink J. Atmos. Chem. 12 367-80
44. Lentner C and West Cadwell N J c1981-1992 Geigy Scientific Tables 8th edn (Basel, Switzerland: Medical education Div., Ciba-Geigy Corp.) pp 165-77