Mapping of neural activity produced by thermal pain in the healthy human spinal cord and brain stem: A functional magnetic resonance imaging study

Magnetic Resonance Imaging

Volumn 29, Issue 3, 2011, Pages 342-352

  Cahill, Catherine M ^a,b   Stroman, Patrick W ^a,b  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

Brainstem; Human; Pain; Sensation; Spinal cord

Indexed keywords

ADULT; ARTICLE; BRAIN FUNCTION; BRAIN MAPPING; CONTROLLED STUDY; EVOKED BRAIN STEM RESPONSE; EVOKED SOMATOSENSORY RESPONSE; EVOKED SPINAL CORD RESPONSE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEAT SENSATION; HUMAN; HUMAN EXPERIMENT; MALE; NOCICEPTIVE STIMULATION; NORMAL HUMAN; OLIVARY NUCLEUS; PAIN THRESHOLD; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RETICULAR FORMATION; SYNAPTIC POTENTIAL; THALAMUS; THERMAL STIMULATION;

ADULT; BRAIN MAPPING; BRAIN STEM; EVOKED POTENTIALS, SOMATOSENSORY; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PAIN; PAIN PERCEPTION; REFERENCE VALUES; SPINAL CORD; THERMOSENSING;

EID: 79952538771     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mri.2010.10.007     Document Type: Article

References (27)

1. Apkarian A.V., Bushnell M.C., Treede R.D., Zubieta J.K. Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 2005, 9(4):463-484.
2. Tracey I., Bushnell M.C. How neuroimaging studies have challenged us to rethink: is chronic pain a disease?. J Pain 2009, 10(11):1113-1120.
3. Brooks J., Tracey I. From nociception to pain perception: imaging the spinal and supraspinal pathways. J Anat 2005, 207(1):19-33.
4. Singer T., Seymour B., O'Doherty J., Kaube H., Dolan R.J., Frith C.D. Empathy for pain involves the affective but not sensory components of pain. Science 2004, 303(5661):1157-1162.
5. Wager T.D., Jonides J., Reading S. Neuroimaging studies of shifting attention: a meta-analysis. Neuroimage 2004, 22(4):1679-1693.
6. Villemure C., Bushnell M.C. Cognitive modulation of pain: how do attention and emotion influence pain processing?. Pain 2002, 95(3):195-199.
7. Zambreanu L., Wise R.G., Brooks J.C., Iannetti G.D., Tracey I. A role for the brainstem in central sensitisation in humans. Evidence from functional magnetic resonance imaging. Pain 2005, 114(3):397-407.
8. Fairhurst M., Wiech K., Dunckley P., Tracey I. Anticipatory brainstem activity predicts neural processing of pain in humans. Pain 2007, 128(1-2):101-110.
9. Stroman P.W. Discrimination of errors from neuronal activity in functional MRI of the human spinal cord by means of general linear model analysis. Magn Reson Med 2006, 56(2):452-456.
10. Agosta F., Valsasina P., Caputo D., Stroman P.W., Filippi M. Tactile-associated recruitment of the cervical cord is altered in patients with multiple sclerosis. Neuroimage 2008, 39(4):1542-1548.
11. Agosta F., Valsasina P., Caputo D., Rocca M.A., Filippi M. Tactile-associated fMRI recruitment of the cervical cord in healthy subjects. Hum Brain Mapp 2007.
12. Valsasina P., Agosta F., Caputo D., Stroman P.W., Filippi M. Spinal fMRI during proprioceptive and tactile tasks in healthy subjects: activity detected using cross-correlation, general linear model and independent component analysis. Neuroradiology 2008, 50:895-902.
13. Stroman P.W. Magnetic resonance imaging of neuronal function in the spinal cord: spinal FMRI. Clin Med Res 2005, 3(3):146-156.
14. Stroman P.W., Kornelsen J., Lawrence J., Malisza K.L. Functional magnetic resonance imaging based on SEEP contrast: response function and anatomical specificity. Magn Reson Imaging 2005, 23(8):843-850.
15. Leitch J.K., Figley C.R., Stroman P.W. Applying functional MRI to the spinal cord and brainstem. Magn Reson Imaging 2010.
16. Stroman P.W., Tomanek B., Krause V., Frankenstein U.N., Malisza K.L. Mapping of neuronal function in the healthy and injured human spinal cord with spinal fMRI. Neuroimage 2002, 17(4):1854-1860.
17. Stroman P.W., Coe B.C., Munoz D.P. Influence of attention focus on neural activity involved with thermal sensations in the human spinal cord. Magn Reson Imaging 2011, 29:9-18.
18. Figley C.R., Stroman P.W. Development and validation of retrospective spinal cord motion time-course estimates (RESPITE) for spin-echo spinal fMRI: improved sensitivity and specificity by means of a motion-compensating general linear model analysis. Neuroimage 2009, 44(2):421-427.
19. Stroman P.W., Figley C.R., Cahill C.M. Spatial normalization, bulk motion correction and coregistration for functional magnetic resonance imaging of the human cervical spinal cord and brainstem. Magn Reson Imaging 2008, 26:809-814.
20. Stroman P.W., Kornelsen J., Bergman A., Krause V., Ethans K., Malisza K.L., et al. Noninvasive assessment of the injured human spinal cord by means of functional magnetic resonance imaging. Spinal Cord 2004, 42(2):59-66.
21. Stroman P.W. Spinal fMRI investigation of human spinal cord function over a range of innocuous thermal sensory stimuli and study-related emotional influences. Magn Reson Imaging 2009, 27:1333-1346.
22. McIntosh A.R., Lobaugh N.J. Partial least squares analysis of neuroimaging data: applications and advances. Neuroimage 2004, 23(Suppl 1):S250-S263.
23. McIntosh A.R., Bookstein F.L., Haxby J.V., Grady C.L. Spatial pattern analysis of functional brain images using partial least squares. Neuroimage 1996, 3(3 Pt 1):143-157.
24. Dostrovsky J.O., Craig A.D. Cooling-specific spinothalamic neurons in the monkey. J Neurophysiol 1996, 76(6):3656-3665.
25. Ploghaus A., Narain C., Beckmann C.F., Clare S., Bantick S., Wise R., et al. Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J Neurosci 2001, 21(24):9896-9903.
26. Villemure C., Bushnell M.C. Mood influences supraspinal pain processing separately from attention. J Neurosci 2009, 29(3):705-715.
27. Logothetis N.K., Pauls J., Augath M., Trinath T., Oeltermann A. Neurophysiological investigation of the basis of the fMRI signal. Nature 2001, 412(6843):150-157.