Functional and unmodified MWNTs for delivery of the water-insoluble drug Carvedilol - A drug-loading mechanism

Applied Surface Science

Volumn 257, Issue 13, 2011, Pages 5663-5670

  Li, Yuting ^a   Wang, Tianyi ^a   Wang, Jing ^a   Jiang, Tongying ^a   Cheng, Gang ^a   Wang, Siling ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Carboxyl MWNTs; Drug delivery; Drug loading mechanism; MWNTs; Poorly water soluble drugs

Indexed keywords

BIOCHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY; FOURIER TRANSFORMS; GAS ADSORPTION; INFRARED SPECTROSCOPY; MULTIWALLED CARBON NANOTUBES (MWCN); PORE SIZE; SCAFFOLDS; SCANNING ELECTRON MICROSCOPY; TARGETED DRUG DELIVERY; THERMOGRAVIMETRIC ANALYSIS; X RAY DIFFRACTION; X RAY PHOTOELECTRON SPECTROSCOPY; YARN;

CARBOXYL MWNTS; DIFFERENT PORE SIZES; DRUG LOADING; DRUG LOADING CAPACITY; FOURIER TRANSFORMATIONS; INCIPIENT WETNESS IMPREGNATION METHOD; MWNTS; POORLY WATER-SOLUBLE DRUGS;

CONTROLLED DRUG DELIVERY;

EID: 79952536754     PISSN: 01694332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apsusc.2011.01.071     Document Type: Article

References (22)

1. R. Bacon Growth, structure, and properties of graphite whiskers J. Appl. Phys. 31 1960 284
2. S. Iijima Helical microtubules of graphitic carbon Nature 354 1991 56 58 (Pubitemid 21896780)
3. M.L. Terranova Special issue on carbon nanotubes Acc. Chem. Res. 35 2002 997 1113
4. T.M. Allen, and P.R. Cullis Drug delivery systems: entering the mainstream Science 303 2004 1818 1822 (Pubitemid 38374867)
5. C.W. Pouton, and L.W. Seymour Key issues in non-viral gene delivery Adv. Drug. Deliv. Rev. 46 2000 187 203 (Pubitemid 33653421)
6. A. Bianco, K. Kostarelos, C.D. Partidos, and M. Prato Biomedical applications of functionalised carbon nanotubes Chem. Commun. (Camb.) 5 2005 571 577 (Pubitemid 40299037)
7. R. Krajcik Functionalization of carbon nanotubes enables non-covalent binding and intracellular delivery of small interfering RNA for efficient knock-down of genes Biochem. Biophys. Res. Commun. 369 2008 595 602
8. X.Y. Yang The preparation of functionalized single walled carbon nanotubes as high efficiency DNA carriers Chin. Chem. Lett. 18 2007 1551 1553
9. R. Krajcik, A. Jung, A. Hirsch, W. Neuhuber, and O. Zolk Functionalization of carbon nanotubes enables non-covalent binding and intracellular delivery of small interfering RNA for efficient knock-down of genes Biochem. Biophys. Res. Commun. 369 2008 595 602
10. M. Foldvari, and M. Bagonluri Carbon nanotubes as functional excipients for nanomedicines. II. Drug delivery and biocompatibility issues Nanomed.: Nanotechnol. Biol. Med. 4 2008 183 200
11. N. Tagmatarchis, and M. Prato Functionalization of carbon nanotubes via 1,3-dipolar cycloadditions J. Mater. Chem. 14 2004 437 439
12. A. Hirsch Functionalization of single-walled carbon nanotubes Angew. Chem. Int. Ed. 41 2002 1853 1859 (Pubitemid 34619593)
13. C.A. Dyke, and J.M. Tour Overcoming the insolubility of carbon nanotubes through high degrees of sidewall functionalization Chem. Eur. J. 10 2004 812 817
14. 3 /Ar plasma treatment Carbon 48 2010 939 948
15. L. Shao, Y.P. Bai, X. Huang, Z.F. Gao, L.L. Meng, Y.D. Huang, and J. Ma Multi-walled carbon nanotubes (MWCNTs) functionalized with amino groups by reacting with supercritical ammonia fluids Mater. Chem. Phys. 116 2009 323 326
16. G. Vukovic, A. Marinkovic, M. Obradovic, V. Radmilovic, M. Colic, R. Aleksic, and P.S. Uskokovic Synthesis, characterization and cytotoxicity of surface amino-functionalized water-dispersible multi-walled carbon nanotubes Appl. Surf. Sci. 255 2009 8067 8075
17. T. Matrab, J. Chancolon, M.M. L'hermite, J.N. Rouzaud, G. Deniau, J.P. Boudou, M.M. Chehimi, and M. Delamar Atom transfer radical polymerization (ATRP) initiated by aryl diazonium salts: a new route for surface modification of multiwalled carbon nanotubes by tethered polymer chains Colloids Surf. A: Physicochem. Eng. Aspects 287 2006 217 221 (Pubitemid 44764819)
18. M.H. Liu, Y.L. Yang, T. Zhu, and Z.F. Liu Chemical modification of single-walled carbon nanotubes with peroxytrifluoroacetic acid Carbon 43 2005 1470 1478 (Pubitemid 40584267)
19. G. Kalita, S. Adhikari, H.R. Aryal, D.C. Ghimre, R. Afre, T. Soga, M. Sharon, and M. Umeno Fluorination of multi-walled carbon nanotubes (MWNTs) via surface wave microwave (SW-MW) plasma treatment Physica E 41 2008 299 303
20. K.J. Ziegler, Z. Gu, H. Peng, E.L. Flor, R.H. Hauge, and R.E. Smalley Controlled oxidative cutting of single-walled carbon nanotubes J. Am. Chem. Soc. 127 2005 1541 1547 (Pubitemid 40204529)
21. T.L. Yue, P.J. McKenna, J.L. Gu, H.Y. Cheng, R.R. Ruffolo Jr., and G.Z. Feuerstein Carvedilol, a new antihypertensive agent, prevents lipid peroxidation and oxidative injury to endothelial cells Hypertension 22 1993 922 928 (Pubitemid 23358101)
22. J. Liu, A.G. Rinzler, H. Dai, J.H. Hanfner, R.K. Bradley, and P.J. Boul Fullerene pipes Science 280 1998 1253 1256 (Pubitemid 28269617)