Effects of triclocarban on intact immature male rat: Augmentation of androgen action

Reproductive Sciences

Volumn 18, Issue 2, 2011, Pages 119-127

  Duleba, Antoni J ^a   Ahmed, Mohamed I ^b   Sun, Meng ^c   Gao, Allen C ^c   Villanueva, Jesus ^a   Conley, Alan J ^d   Turgeon, Judith L ^a   Benirschke, Kurt ^e   Gee, Nancy A ^f   Chen, Jiangang ^f   Green, Peter G ^d   Lasley, Bill L ^f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BENHA UNIVERSITY   (Egypt)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Androgen receptor; Endocrine disrupting substance; Luteinizing hormone; Testosterone; Triclocarban

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; LUTEINIZING HORMONE; TESTOSTERONE; TRICLOCARBAN;

ACCESSORY SEX ORGAN; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN LNCAP; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY MASS; LIVER WEIGHT; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NONHUMAN; ORGAN WEIGHT; PENIS GLANS; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE VENTRAL LOBE; RAT; SEMINAL VESICLE; TESTIS SIZE; TESTOSTERONE BLOOD LEVEL;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; BODY WEIGHT; CARBANILIDES; CELL LINE, TUMOR; HUMANS; LUTEINIZING HORMONE; MALE; ORGAN SIZE; PROSTATE; PROSTATIC NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; SEXUAL MATURATION; TESTOSTERONE; TRANSCRIPTION, GENETIC; WATER;

EID: 79952522623     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719110382581     Document Type: Article

References (35)

1. Cha J, Cupples AM. Detection of the antimicrobials triclocarban and triclosan in agricultural soils following land application of municipal biosolids. Water Res. 2009;43(9):2522-2530.
2. Halden RU, Paull DH. Co-occurrence of triclocarban and triclosan in U.S. water resources. Environ Sci Technol. 2005;39(6):1420-1426. (Pubitemid 40387693)
3. Heidler J, Sapkota A, Halden RU. Partitioning, persistence, and accumulation in digested sludge of the topical antiseptic triclocarban during wastewater treatment. Environ Sci Technol. 2006;40(11):3634-3639. (Pubitemid 43830972)
4. Miller TR, Heidler J, Chillrud SN, et al. Fate of triclosan and evidence for reductive dechlorination of triclocarban in estuarine sediments. Environ Sci Technol. 2008;42(12):4570-4576. (Pubitemid 351842408)
5. Sapkota A, Heidler J, Halden RU. Detection of triclocarban and two co-contaminating chlorocarbanilides in US aquatic environments using isotope dilution liquid chromatography tandem mass spectrometry. Environ Res. 2007;103(1):21-29. (Pubitemid 44894402)
6. Wu C, Spongberg AL, Witter JD. Adsorption and degradation of triclosan and triclocarban in soils and biosolids-amended soils. J Agric Food Chem. 2009;57(11):4900-4905.
7. Nolen GA, Dierckman TA. Reproduction and teratogenic studies of a 2:1 mixture of 3,4,4'-trichlorocarbanilide and 3-trifluoromethyl-4,4′- dichlorocarbanilide in rats and rabbits. Toxicol Appl Pharmacol. 1979;51(3):417-425.
8. Chen J, Ahn KC, Gee NA, et al. Triclocarban enhances testosterone action: a new type of endocrine disruptor? Endocrinology. 2008;149(3):1173-1179.
9. Chen J, Sowers MR, Moran FM, et al. Circulating bioactive androgens in midlife women. J Clin Endocrinol Metab. 2006;91(11):4387-4394. (Pubitemid 44833414)
10. Abbott DH, Padmanabhan V, Dumesic DA. Contributions of androgen and estrogen to fetal programming of ovarian dysfunction. Reprod Biol Endocrinol. 2006;4:17.
11. Atanassova N, McKinnell C, Walker M, et al. Permanent effects of neonatal estrogen exposure in rats on reproductive hormone levels, Sertoli cell number, and the efficiency of spermatogenesis in adulthood. Endocrinology. 1999;140(11):5364-5373.
12. Hotchkiss AK, Furr J, Makynen EA, Ankley GT, Gray LE Jr. In utero exposure to the environmental androgen trenbolone masculinizes female Sprague-Dawley rats. Toxicol Lett. 2007;174(1-3):31-41.
13. Hotchkiss AK, Nelson RJ. An environmental androgen, 17beta-trenbolone, affects delayed-type hypersensitivity and reproductive tissues in male mice. J Toxicol Environ Health A. 2007;70(2):138-140.
14. Moore RW, Rudy TA, Lin TM, Ko K, Peterson RE. Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate. Environ Health Perspect. 2001;109(3):229-237. (Pubitemid 32331513)
15. Corbin CJ, Moran FM, Vidal JD, et al. Biochemical assessment of limits to estrogen synthesis in porcine follicles. Biol Reprod. 2003;69(2):390-397. (Pubitemid 36885940)
16. Gercel-Taylor C. Diphenylamine assay of DNA fragmentation for chemosensitivity testing. Methods Mol Med. 2005;111:79-82.
17. Matteri RL, Roser JF, Baldwin DM, Lipovetsky V, Papkoff H. Characterization of a monoclonal antibody which detects luteinizing hormone from diverse mammalian species. Domest Anim Endocrinol. 1987;4(3):157-165.
18. Yeh S, Chang C. Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proc Natl Acad Sci U S A. 1996;93(11):5517-5521.
19. Zhang J, Thomas TZ, Kasper S, Matusik RJ. A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology. 2000;141(12):4698-4710. (Pubitemid 32055150)
20. Diamanti-Kandarakis E, Palioura E, Kandarakis SA, Koutsilieris M. The impact of endocrine disruptors on endocrine targets. Horm Metab Res. 2010;42(8):543-552.
21. Kennel PF, Pallen CT, Bars RG. Evaluation of the rodent Hershberger assay using three reference endocrine disrupters (androgen and antiandrogens). Reprod Toxicol. 2004;18(1):63-73. (Pubitemid 38175448)
22. Prins GS. Neonatal estrogen exposure induces lobe-specific alterations in adult rat prostate androgen receptor expression. Endocrinology. 1992;130(6):3703-3714.
23. Yamashita S. Localization of estrogen and androgen receptors in male reproductive tissues of mice and rats. Anat Rec A Discov Mol Cell Evol Biol. 2004;279(2):768-778. (Pubitemid 39038470)
24. Horoszewicz JS, Leong SS, Chu TM, et al. The LNCaP cell line - a new model for studies on human prostatic carcinoma. Prog Clin Biol Res. 1980;37:115-132.
25. Horoszewicz JS, Leong SS, Kawinski E, et al. LNCaP model of human prostatic carcinoma. Cancer Res. 1983;43:1809-1818. (Pubitemid 13122588)
26. Wu HC, Hsieh JT, Gleave ME, Brown NM, Pathak S, Chung LW. Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells. Int J Cancer. 1994;57(3):406-412. (Pubitemid 24168617)
27. Hakola K, Pierroz DD, Aebi A, Vuagnat BA, Aubert ML, Huhtaniemi I. Dose and time relationships of intravenously injected rat recombinant luteinizing hormone and testicular testosterone secretion in the male rat. Biol Reprod. 1998;59(2):338-343. (Pubitemid 28354874)
28. Owens W, Zeiger E, Walker M, Ashby J, Onyon L, Gray LE Jr. The OECD program to validate the rat Hershberger bioassay to screen compounds for in vivo androgen and antiandrogen responses. Phase 1: use of a potent agonist and a potent antagonist to test the standardized protocol. Environ Health Perspect. 2006;114(8):1259-1265.
29. Huhtaniemi IT, Nozu K, Warren DW, Dufau ML, Catt KJ. Acquisition of regulatory mechanisms for gonadotropin receptors and steroidogenesis in the maturing rat testis. Endocrinology. 1982;111(5):1711-1720.
30. Zirkin BR, Ewing LL. Leydig cell differentiation during maturation of the rat testis: a stereological study of cell number and ultrastructure. Anat Rec. 1987;219(2):157-163. (Pubitemid 17149853)
31. Nazian SJ, Mahesh VB. Hypothalamic, pituitary, testicular, and secondary organ functions and interactions during the sexual maturation of the male rat. Arch Androl. 1980;4(4):283-303. (Pubitemid 10118326)
32. Bagatell CJ, Dahl KD, Bremner WJ. The direct pituitary effect of testosterone to inhibit gonadotropin secretion in men is partially mediated by aromatization to estradiol. J Androl. 1994;15(1):15-21. (Pubitemid 24061781)
33. Lindzey J, Wetsel WC, Couse JF, Stoker T, Cooper R, Korach KS. Effects of castration and chronic steroid treatments on hypothalamic gonadotropin- releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice. Endocrinology. 1998;139(10):4092-4101. (Pubitemid 28513693)
34. Resko JA, Connolly PB, Roselli CE, Abdelgadir SE, Choate JV. Differential effects of aromatase inhibition on luteinizing hormone secretion in intact and castrated male cynomolgus macaques. J Clin Endocrinol Metab. 1993;77(6):1529-1534. (Pubitemid 24000908)
35. Roselli CE, Resko JA. Regulation of hypothalamic luteinizing hormone-releasing hormone levels by testosterone and estradiol in male rhesus monkeys. Brain Res. 1990;509(2):343-346. (Pubitemid 20055886)