Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 7, 2011, Pages 1962-1964

  Kitajima, Mariko ^a   Iwai, Masumi ^a   Kikura Hanajiri, Ruri ^b   Goda, Yukihiro ^b   Iida, Mitsuru ^c   Yabushita, Hisatoshi ^c   Takayama, Hiromitsu ^a  

^a CHIBA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Antagonist; Cannabinoid; CB1 receptor; Iboga; Indole alkaloid; Voacanga

Indexed keywords

3,6 OXIDOVOACANGINE; 5 HYDROXY 3,6 OXIDOVOACANGINE; CANNABINOID 1 RECEPTOR ANTAGONIST; INDOLE ALKALOID; RIMONABANT; UNCLASSIFIED DRUG; VOACAMINE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ACTIVITY; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; VOACANGA; VOACANGA AFRICANA;

DRUG DISCOVERY; INDOLE ALKALOIDS; MOLECULAR STRUCTURE; PLANT EXTRACTS; RECEPTOR, CANNABINOID, CB1; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; VOACANGA;

VOACANGA; VOACANGA AFRICANA;

EID: 79952490405     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.02.036     Document Type: Article

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