메뉴 건너뛰기




Volumn 28, Issue 2, 2011, Pages 200-214

Cancer immunotherapy and nanomedicine

Author keywords

adjuvant; cancer immunotherapy; cancer vaccine; nano; tumor immunoediting

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CANCER VACCINE; CISPLATIN; CPG OLIGODEOXYNUCLEOTIDE; CYCLOPHOSPHAMIDE; DENDRITIC CELL VACCINE; DNA VACCINE; DOXORUBICIN; FLUOROURACIL; GAMMA INTERFERON; GEMCITABINE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 21; LIPOSOME; NANOPARTICLE; OBLIMERSEN; PEPTIDE VACCINE; PLATINUM; PROTEIN E6; PROTEIN E7; PROVENGE; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR AGONIST; WART VIRUS VACCINE;

EID: 79952486562     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0258-8     Document Type: Review
Times cited : (77)

References (163)
  • 1
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma, and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • DOI 10.1038/35074122
    • Shankaran V, Ikeda H, Bruce AT, White JM, Swanson PE, Old LJ, et al. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature. 2001;410:1107-11. (Pubitemid 32391043)
    • (2001) Nature , vol.410 , Issue.6832 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 2
    • 0022573876 scopus 로고
    • Separation of tumor-infiltrating lymphocytes from tumor cells in human solid tumors. A comparison between velocity sedimentation and discontinuous density gradients
    • DOI 10.1016/0022-1759(86)90079-7
    • Whiteside TL, Miescher S, MacDonald HR, Von Fliedner V. Separation of tumor-infiltrating lymphocytes from tumor cells in human solid tumors. A comparison between velocity sedimentation and discontinuous density gradients. J Immunol Methods. 1986;90:221-33. (Pubitemid 16089014)
    • (1986) Journal of Immunological Methods , vol.90 , Issue.2 , pp. 221-233
    • Whiteside, T.L.1    Miescher, S.2    MacDonald, H.R.3    Von Fliedner, V.4
  • 3
    • 2542430341 scopus 로고    scopus 로고
    • The three Es of cancer immunoediting
    • DOI 10.1146/annurev.immunol.22.012703.104803
    • Dunn GP, Old LJ, Schreiber RD. The three Es of cancer immunoediting. Annu Rev Immunol. 2004;22:329-60. (Pubitemid 38680426)
    • (2004) Annual Review of Immunology , vol.22 , pp. 329-360
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 4
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • DOI 10.1016/j.immuni.2004.07.017, PII S1074761304002092
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity. 2004;21:137-48. (Pubitemid 39094044)
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 6
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9:162-74.
    • (2009) Nat Rev Immunol , vol.9 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 7
    • 33750290402 scopus 로고    scopus 로고
    • Mechanisms of tumor escape: Role of tumor microenvironment in inducing apoptosis of cytolytic effector cells
    • DOI 10.1007/s00005-006-0038-7
    • Poggi A, Zocchi MR. Mechanisms of tumor escape: role of tumor microenvironment in inducing apoptosis of cytolytic effector cells. Arch Immunol Ther Exp (Warsz). 2006;54:323-33. (Pubitemid 44627669)
    • (2006) Archivum Immunologiae et Therapiae Experimentalis , vol.54 , Issue.5 , pp. 323-333
    • Poggi, A.1    Zocchi, M.R.2
  • 10
    • 0025856106 scopus 로고
    • Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity
    • Schmidt-Wolf IG, Negrin RS, Kiem HP, Blume KG, Weissman IL. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J Exp Med. 1991;174:139-49.
    • (1991) J Exp Med , vol.174 , pp. 139-149
    • Schmidt-Wolf, I.G.1    Negrin, R.S.2    Kiem, H.P.3    Blume, K.G.4    Weissman, I.L.5
  • 11
    • 0032817103 scopus 로고    scopus 로고
    • Acquired immunity in nude mice induced by expression of the IL-2 or IL- 4 gene in human pancreatic carcinoma cells and anti-tumor effect generated by in vivo gene transfer using retrovirus
    • DOI 10.1002/(SICI)1097-0215(19990812)82:4<549::AID-IJC13>3.0.CO;2-0
    • Kimura M, Yoshida Y, Narita M, Takenaga K, Takenouchi T, Yamaguchi T, et al. Acquired immunity in nude mice induced by expression of the IL-2 or IL-4 gene in human pancreatic carcinoma cells and anti-tumor effect generated by in vivo gene transfer using retrovirus. Int J Cancer. 1999;82:549-55. (Pubitemid 29343455)
    • (1999) International Journal of Cancer , vol.82 , Issue.4 , pp. 549-555
    • Kimura, M.1    Yoshida, Y.2    Narita, M.3    Takenaga, K.4    Takenouchi, T.5    Yamaguchi, T.6    Saisho, H.7    Sakiyama, S.8    Tagawa, M.9
  • 12
    • 67649373027 scopus 로고    scopus 로고
    • Antitumor activity of cytokine-induced killer cells in nude mouse xenograft model
    • Kim HM, Kang JS, Lim J, Kim JY, Kim YJ, Lee SJ, et al. Antitumor activity of cytokine-induced killer cells in nude mouse xenograft model. Arch Pharm Res. 2009;32:781-7.
    • (2009) Arch Pharm Res , vol.32 , pp. 781-787
    • Kim, H.M.1    Kang, J.S.2    Lim, J.3    Kim, J.Y.4    Kim, Y.J.5    Lee, S.J.6
  • 14
    • 0032471712 scopus 로고    scopus 로고
    • Durability of complete responses in patients with metastatic cancer treated with high-dose interleukin-2: Identification of the antigens mediating response
    • DOI 10.1097/00000658-199809000-00004
    • Rosenberg SA, Yang JC, White DE, Steinberg SM. Durability of complete responses in patients with metastatic cancer treated with high-dose interleukin-2: identification of the antigens mediating response. Ann Surg. 1998;228:307-19. (Pubitemid 30191694)
    • (1998) Annals of Surgery , vol.228 , Issue.3 , pp. 307-319
    • Rosenberg, S.A.1    Yang, J.C.2    White, D.E.3    Steinberg, S.M.4
  • 15
    • 64549132600 scopus 로고    scopus 로고
    • The application of high-dose interleukin-2 for metastatic renal cell carcinoma
    • McDermott DF. The application of high-dose interleukin-2 for metastatic renal cell carcinoma. Med Oncol. 2009;26 Suppl 1:13-7.
    • (2009) Med Oncol , vol.26 , Issue.SUPPL. 1 , pp. 13-17
    • McDermott, D.F.1
  • 18
    • 0036836168 scopus 로고    scopus 로고
    • Managing toxicities of high-dose interleukin-2
    • Williston Park
    • Schwartz RN, Stover L, Dutcher J. Managing toxicities of high-dose interleukin-2. Oncology (Williston Park). 2002;16:11-20.
    • (2002) Oncology , vol.16 , pp. 11-20
    • Schwartz, R.N.1    Stover, L.2    Dutcher, J.3
  • 20
    • 42949139835 scopus 로고    scopus 로고
    • Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma
    • Thompson JA, Curti BD, Redman BG, Bhatia S, Weber JS, Agarwala SS, et al. Phase I study of recombinant interleukin-21 in patients with metastatic melanoma and renal cell carcinoma. J Clin Oncol. 2008;26:2034-9.
    • (2008) J Clin Oncol , vol.26 , pp. 2034-2039
    • Thompson, J.A.1    Curti, B.D.2    Redman, B.G.3    Bhatia, S.4    Weber, J.S.5    Agarwala, S.S.6
  • 21
    • 0030766468 scopus 로고    scopus 로고
    • Interleukin 18 induces the sequential activation of natural killer cells and cytotoxic T lymphocytes to protect syngeneic mice from transplantation with Meth A sarcoma
    • Micallef MJ, Tanimoto T, Kohno K, Ikeda M, Kurimoto M. Interleukin 18 induces the sequential activation of natural killer cells and cytotoxic T lymphocytes to protect syngeneic mice from transplantation with Meth A sarcoma. Cancer Res. 1997;57:4557-63. (Pubitemid 27441061)
    • (1997) Cancer Research , vol.57 , Issue.20 , pp. 4557-4563
    • Micallef, M.J.1    Tanimoto, T.2    Kohno, K.3    Ikeda, M.4    Kurimoto, M.5
  • 22
    • 33847352726 scopus 로고    scopus 로고
    • Clinical and biological effects of recombinant human interleukin-18 administered by intravenous infusion to patients with advanced cancer
    • Robertson MJ, Mier JW, Logan T, Atkins M, Koon H, Koch KM, et al. Clinical and biological effects of recombinant human interleukin-18 administered by intravenous infusion to patients with advanced cancer. Clin Cancer Res. 2006;12:4265-73.
    • (2006) Clin Cancer Res , vol.12 , pp. 4265-4273
    • Robertson, M.J.1    Mier, J.W.2    Logan, T.3    Atkins, M.4    Koon, H.5    Koch, K.M.6
  • 23
    • 50349092728 scopus 로고    scopus 로고
    • A dose-escalation study of recombinant human interleukin-18 using two different schedules of administration in patients with cancer
    • Robertson MJ, Kirkwood JM, Logan TF, Koch KM, Kathman S, Kirby LC, et al. A dose-escalation study of recombinant human interleukin-18 using two different schedules of administration in patients with cancer. Clin Cancer Res. 2008;14:3462-9.
    • (2008) Clin Cancer Res , vol.14 , pp. 3462-3469
    • Robertson, M.J.1    Kirkwood, J.M.2    Logan, T.F.3    Koch, K.M.4    Kathman, S.5    Kirby, L.C.6
  • 24
    • 73249137169 scopus 로고    scopus 로고
    • Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL- 18
    • Alagkiozidis I, Facciabene A, Carpenito C, Benencia F, Jonak Z, Adams S, et al. Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL- 18. J Transl Med. 2009;7:104.
    • (2009) J Transl Med , vol.7 , pp. 104
    • Alagkiozidis, I.1    Facciabene, A.2    Carpenito, C.3    Benencia, F.4    Jonak, Z.5    Adams, S.6
  • 25
    • 0018143273 scopus 로고
    • Enhanced NK cell activity in mice injected with interferon and interferon inducers
    • Gidlund M, Orn A, Wigzell H, Senik A, Gresser I. Enhanced NK cell activity in mice injected with interferon and interferon inducers. Nature. 1978;273:759-61. (Pubitemid 8357090)
    • (1978) Nature , vol.273 , Issue.5665 , pp. 759-761
    • Gidlund, M.1    Orn, A.2    Wigzell, H.3
  • 26
    • 0018904459 scopus 로고
    • Interferon enhances the expression of Fcgamma receptors
    • Fridman WH, Gresser I, Bandu MT, Aguet M, Neauport-Sautes C. Interferon enhances the expression of Fc gamma receptors. J Immunol. 1980;124:2436-41. (Pubitemid 10113344)
    • (1980) Journal of Immunology , vol.124 , Issue.5 , pp. 2436-2441
    • Fridman, W.H.1    Gresser, I.2    Bandu, M.T.3
  • 27
    • 0019946931 scopus 로고
    • Interferon inhibits the generation of allospecific suppressor T lymphocytes
    • DOI 10.1084/jem.155.6.1610
    • Fradelizi D, Gresser I. Interferon inhibits the generation of allospecific suppressor T lymphocytes. J Exp Med. 1982;155:1610-22. (Pubitemid 12074202)
    • (1982) Journal of Experimental Medicine , vol.155 , Issue.6 , pp. 1610-1622
    • Fradelizi, D.1    Gresser, I.2
  • 28
    • 0014688665 scopus 로고
    • Exogenous interferon and inducers of interferon in the treatment Balb-c mice inoculated with RC19 tumour cells
    • Gresser I, Bourali C. Exogenous interferon and inducers of interferon in the treatment Balb-c mice inoculated with RC19 tumour cells. Nature. 1969;223:844-5.
    • (1969) Nature , vol.223 , pp. 844-845
    • Gresser, I.1    Bourali, C.2
  • 29
    • 0014828095 scopus 로고
    • Antitumor effects of interferon preparations in mice
    • Gresser I, Bourali C. Antitumor effects of interferon preparations in mice. J Natl Cancer Inst. 1970;45:365-76.
    • (1970) J Natl Cancer Inst , vol.45 , pp. 365-376
    • Gresser, I.1    Bourali, C.2
  • 30
    • 0015519425 scopus 로고
    • Inhibition by interferon preparations of a solid malignant tumour and pulmonary metastasis in mice
    • Gresser I, Bourali-Maury C. Inhibition by interferon preparations of a solid malignant tumour and pulmonary metastasis in mice. Nat New Biol. 1972;236:78-9.
    • (1972) Nat New Biol , vol.236 , pp. 78-79
    • Gresser, I.1    Bourali-Maury, C.2
  • 31
    • 0021848512 scopus 로고
    • Effects of recombinant leukocyte interferon (rIFN-alphaA) on tumour growth and immune responses in patients with metastatic melanoma
    • Hersey P, Hasic E, MacDonald M, Edwards A, Spurling A, Coates AS, et al. Effects of recombinant leukocyte interferon (rIFN-alpha A) on tumour growth and immune responses in patients with metastatic melanoma. Br J Cancer. 1985;51:815-26. (Pubitemid 15056995)
    • (1985) British Journal of Cancer , vol.51 , Issue.6 , pp. 815-826
    • Hersey, P.1    Hasic, E.2    MacDonald, M.3
  • 32
    • 0023262245 scopus 로고
    • Phase I/II trial of interferon-beta-serine in patients with renal cell carcinoma: Immunological and biological effects
    • Rinehart JJ, Young D, Laforge J, Colborn D, Neidhart JA. Phase I/II trial of interferon-beta-serine in patients with renal cell carcinoma: immunological and biological effects. Cancer Res. 1987;47:2481-5. (Pubitemid 17099217)
    • (1987) Cancer Research , vol.47 , Issue.9 , pp. 2481-2485
    • Rinehart, J.J.1    Young, D.2    Laforge, J.3
  • 33
    • 0023039222 scopus 로고
    • Alpha interferon treatment of low-grade B-cell non-Hodgkin's lymphomas, cutaneous T-cell lymphomas, and chronic lymphocytic leukemia
    • Foon KA, Roth MS, Bunn Jr PA. Alpha interferon treatment of low-grade B-cell non-Hodgkin's lymphomas, cutaneous T-cell lymphomas, and chronic lymphocytic leukemia. Semin Oncol. 1986;13:35-42. (Pubitemid 17208248)
    • (1986) Seminars in Oncology , vol.13 , Issue.3 SUPPL. 2 , pp. 35-42
    • Foon, K.A.1    Roth, M.S.2    Bunn Jr., P.A.3
  • 34
    • 0021133667 scopus 로고
    • Phase II study of low-dose recombinant leukocyte A interferon in disseminated malignant melanoma
    • Creagan ET, Ahmann DL, Green SJ, Long HJ, Frytak S, O'Fallon JR, et al. Phase II study of low-dose recombinant leukocyte A interferon in disseminated malignant melanoma. J Clin Oncol. 1984;2:1002-5. (Pubitemid 14026256)
    • (1984) Journal of Clinical Oncology , vol.2 , Issue.9 , pp. 1002-1005
    • Creagan, E.T.1    Ahmann, D.L.2    Green, S.J.3
  • 35
    • 0029041749 scopus 로고
    • UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: Improved survival irrespective of cytogenetic response
    • The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult Leukaemia
    • Allan NC, Richards SM, Shepherd PC. UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult Leukaemia. Lancet. 1995;345:1392-7.
    • (1995) Lancet , vol.345 , pp. 1392-1397
    • Allan, N.C.1    Richards, S.M.2    Shepherd, P.C.3
  • 36
    • 2942642267 scopus 로고    scopus 로고
    • Phase 2 trial of interferon-beta as second-line treatment of ovarian cancer, fallopian tube cancer, or primary carcinoma of the peritoneum
    • DOI 10.1159/000079480
    • Markman M, Belinson J, Webster K, Zanotti K, Morrison B, Jacobs B, et al. Phase 2 trial of interferon-beta as second-line treatment of ovarian cancer, fallopian tube cancer, or primary carcinoma of the peritoneum. Oncology. 2004;66:343-6. (Pubitemid 39194354)
    • (2004) Oncology , vol.66 , Issue.5 , pp. 343-346
    • Markman, M.1    Belinson, J.2    Webster, K.3    Zanotti, K.4    Morrison, B.5    Jacobs, B.6    Borden, E.7    Lindner, D.8
  • 41
    • 0037479853 scopus 로고    scopus 로고
    • IFN-gamma induces apoptosis in ovarian cancer cells in vivo and in vitro
    • Wall L, Burke F, Barton C, Smyth J, Balkwill F. IFN-gamma induces apoptosis in ovarian cancer cells in vivo and in vitro. Clin Cancer Res. 2003;9:2487-96. (Pubitemid 36842088)
    • (2003) Clinical Cancer Research , vol.9 , Issue.7 , pp. 2487-2496
    • Wall, L.1    Burke, F.2    Barton, C.3    Smyth, J.4    Balkwill, F.5
  • 42
    • 0032529634 scopus 로고    scopus 로고
    • Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines
    • Johnsen A, France J, Sy MS, Harding CV. Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines. Cancer Res. 1998;58:3660-7. (Pubitemid 28376566)
    • (1998) Cancer Research , vol.58 , Issue.16 , pp. 3660-3667
    • Johnsen, A.1    France, J.2    Sy, M.-S.3    Harding, C.V.4
  • 43
    • 10544242200 scopus 로고    scopus 로고
    • Molecular basis for lack of expression of HLA class I antigens in human small-cell lung carcinoma cell lines
    • DOI 10.1002/(SICI)1097-0215(19961127)68:5<629::AID-IJC13>3.0.CO;2-X
    • Singal DP, Ye M, Qiu X. Molecular basis for lack of expression of HLA class I antigens in human small-cell lung carcinoma cell lines. Int J Cancer. 1996;68:629-36. (Pubitemid 26414525)
    • (1996) International Journal of Cancer , vol.68 , Issue.5 , pp. 629-636
    • Singal, D.P.1    Ming, Y.E.2    Qiu, X.3
  • 45
    • 63749113820 scopus 로고    scopus 로고
    • A phase II study of GM-CSF and rIFNgamma1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer
    • Schmeler KM, Vadhan-Raj S, Ramirez PT, Apte SM, Cohen L, Bassett RL, et al. A phase II study of GM-CSF and rIFNgamma1b plus carboplatin for the treatment of recurrent, platinum-sensitive ovarian, fallopian tube and primary peritoneal cancer. Gynecol Oncol. 2009;113:210-5.
    • (2009) Gynecol Oncol , vol.113 , pp. 210-215
    • Schmeler, K.M.1    Vadhan-Raj, S.2    Ramirez, P.T.3    Apte, S.M.4    Cohen, L.5    Bassett, R.L.6
  • 47
    • 33745938818 scopus 로고    scopus 로고
    • Interferon-gamma in combination with carboplatin and paclitaxel as a safe and effective first-line treatment option for advanced ovarian cancer: Results of a phase I/II study
    • DOI 10.1111/j.1525-1438.2006.00622.x
    • Marth C, Windbichler GH, Hausmaninger H, Petru E, Estermann K, Pelzer A, et al. Interferon-gamma in combination with carboplatin and paclitaxel as a safe and effective first-line treatment option for advanced ovarian cancer: results of a phase I/II study. Int J Gynecol Cancer. 2006;16:1522-8. (Pubitemid 44060374)
    • (2006) International Journal of Gynecological Cancer , vol.16 , Issue.4 , pp. 1522-1528
    • Marth, C.1    Windbichler, G.H.2    Hausmaninger, H.3    Petru, E.4    Estermann, K.5    Pelzer, A.6    Mueller-Holzner, E.7
  • 48
    • 42749083267 scopus 로고    scopus 로고
    • Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carboplatin/ paclitaxel alone for first-line treatment of advanced ovarian and primary peritoneal carcinomas: Results from a prospectively designed analysis of progression-free survival
    • Alberts DS, Marth C, Alvarez RD, Johnson G, Bidzinski M, Kardatzke DR, et al. Randomized phase 3 trial of interferon gamma-1b plus standard carboplatin/paclitaxel versus carboplatin/ paclitaxel alone for first-line treatment of advanced ovarian and primary peritoneal carcinomas: results from a prospectively designed analysis of progression-free survival. Gynecol Oncol. 2008;109:174-81.
    • (2008) Gynecol Oncol , vol.109 , pp. 174-181
    • Alberts, D.S.1    Marth, C.2    Alvarez, R.D.3    Johnson, G.4    Bidzinski, M.5    Kardatzke, D.R.6
  • 49
    • 0027102720 scopus 로고
    • Interferon-alpha, interferon-gamma and sizofiran in the adjuvant therapy in ovarian cancer - A preliminary trial
    • DOI 10.1007/BF02179044
    • Chen JT, Hasumi K, Masubuchi K. Interferon-alpha, interferon-gamma and sizofiran in the adjuvant therapy in ovarian cancer-a preliminary trial. Biotherapy. 1992;5:275-80. (Pubitemid 23024372)
    • (1992) Biotherapy , vol.5 , Issue.4 , pp. 275-280
    • Chen, J.-T.1    Hasumi, K.2    Masabuchi, K.3
  • 51
    • 34548598702 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1111/j.1365-2567.2007.02651.x
    • Liu G, Zhao Y. Toll-like receptors and immune regulation: their direct and indirect modulation on regulatory CD4+ CD25+ T cells. Immunology. 2007;122:149-56. (Pubitemid 47389958)
    • (2007) Immunology , vol.122 , Issue.2 , pp. 149-156
    • Liu, G.1    Zhao, Y.2
  • 54
    • 33845542139 scopus 로고    scopus 로고
    • Toll-like receptor agonists in the treatment of chronic lymphocytic leukemia
    • DOI 10.1038/sj.leu.2404456, PII 2404456
    • Spaner DE, Masellis A. Toll-like receptor agonists in the treatment of chronic lymphocytic leukemia. Leukemia. 2007;21:53-60. (Pubitemid 44921834)
    • (2007) Leukemia , vol.21 , Issue.1 , pp. 53-60
    • Spaner, D.E.1    Masellis, A.2
  • 56
    • 33748683549 scopus 로고    scopus 로고
    • Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma
    • DOI 10.1097/01.cji.0000211304.60126.8f, PII 0000237120060900000010
    • Link BK, Ballas ZK, Weisdorf D, Wooldridge JE, Bossler AD, Shannon M, et al. Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma. J Immunother. 2006;29:558-68. (Pubitemid 44395280)
    • (2006) Journal of Immunotherapy , vol.29 , Issue.5 , pp. 558-568
    • Link, B.K.1    Ballas, Z.K.2    Weisdorf, D.3    Wooldridge, J.E.4    Bossler, A.D.5    Shannon, M.6    Rasmussen, W.L.7    Krieg, A.M.8    Weiner, G.J.9
  • 58
    • 41549108107 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates an antitumor host response induced by Salmonella choleraesuis
    • Lee CH, Wu CL, Shiau AL. Toll-like receptor 4 mediates an antitumor host response induced by Salmonella choleraesuis. Clin Cancer Res. 2008;14:1905-12.
    • (2008) Clin Cancer Res , vol.14 , pp. 1905-1912
    • Lee, C.H.1    Wu, C.L.2    Shiau, A.L.3
  • 59
    • 33645727988 scopus 로고    scopus 로고
    • TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer
    • Kelly MG, Alvero AB, Chen R, Silasi DA, Abrahams VM, Chan S, et al. TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. Cancer Res. 2006;66:3859-68.
    • (2006) Cancer Res , vol.66 , pp. 3859-3868
    • Kelly, M.G.1    Alvero, A.B.2    Chen, R.3    Silasi, D.A.4    Abrahams, V.M.5    Chan, S.6
  • 60
    • 70350117978 scopus 로고    scopus 로고
    • KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells
    • Kim KH, Xie Y, Tytler EM, Woessner R, Mor G, Alvero AB. KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells. J Transl Med. 2009;7:63.
    • (2009) J Transl Med , vol.7 , pp. 63
    • Kim, K.H.1    Xie, Y.2    Tytler, E.M.3    Woessner, R.4    Mor, G.5    Alvero, A.B.6
  • 62
    • 1842631153 scopus 로고    scopus 로고
    • Immunotherapeutic uses of CpG oligodeoxynucleotides
    • Klinman DM. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat Rev Immunol. 2004;4:249-58. (Pubitemid 38478660)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.4 , pp. 249-258
    • Klinman, D.M.1
  • 63
    • 62649158435 scopus 로고    scopus 로고
    • Antitumor activity of G3139 lipid nanoparticles (LNPs)
    • Pan X, Chen L, Liu S, Yang X, Gao JX, Lee RJ. Antitumor activity of G3139 lipid nanoparticles (LNPs). Mol Pharm. 2009;6:211-20.
    • (2009) Mol Pharm , vol.6 , pp. 211-220
    • Pan, X.1    Chen, L.2    Liu, S.3    Yang, X.4    Gao, J.X.5    Lee, R.J.6
  • 64
    • 41949094382 scopus 로고    scopus 로고
    • Brain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles
    • Schneider T, Becker A, Ringe K, Reinhold A, Firsching R, Sabel BA. Brain tumor therapy by combined vaccination and antisense oligonucleotide delivery with nanoparticles. J Neuroimmunol. 2008;195:21-7.
    • (2008) J Neuroimmunol , vol.195 , pp. 21-27
    • Schneider, T.1    Becker, A.2    Ringe, K.3    Reinhold, A.4    Firsching, R.5    Sabel, B.A.6
  • 65
    • 0024378215 scopus 로고
    • Antibody-dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony-stimulating factor. Induction of efficient antibody-mediated antitumor cytotoxicity not detected by isotope release assays
    • Munn DH, Cheung NK. Antibody-dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony-stimulating factor. Induction of efficient antibody-mediated antitumor cytotoxicity not detected by isotope release assays. J Exp Med. 1989;170:511-26. (Pubitemid 19204278)
    • (1989) Journal of Experimental Medicine , vol.170 , Issue.2 , pp. 511-526
    • Munn, D.H.1    Cheung, N.V.2
  • 66
    • 0025326953 scopus 로고
    • Phagocytosis of tumor cells by human monocytes cultured in recombinant macrophage colony-stimulating factor
    • DOI 10.1084/jem.172.1.231
    • Munn DH, Cheung NK. Phagocytosis of tumor cells by human monocytes cultured in recombinant macrophage colonystimulating factor. J Exp Med. 1990;172:231-7. (Pubitemid 20217264)
    • (1990) Journal of Experimental Medicine , vol.172 , Issue.1 , pp. 231-237
    • Munn, D.H.1    Cheung, N.-K.V.2
  • 67
    • 11844273237 scopus 로고    scopus 로고
    • Recombinant bispecific antibodies for cancer therapy
    • DOI 10.1111/j.1745-7254.2005.00008.x
    • Kontermann RE. Recombinant bispecific antibodies for cancer therapy. Acta Pharmacol Sin. 2005;26:1-9. (Pubitemid 40093233)
    • (2005) Acta Pharmacologica Sinica , vol.26 , Issue.1 , pp. 1-9
    • Kontermann, R.E.1
  • 72
    • 79952484592 scopus 로고    scopus 로고
    • http://www-bimas.cit.nih.gov/molbio/hla-bind/index.shtml.
  • 73
    • 79952484311 scopus 로고    scopus 로고
    • http://www.syfpeithi.de/Scripts/MHCServer.dll/EpitopePrediction.htm.
  • 74
    • 79952486360 scopus 로고    scopus 로고
    • http://bioinformatics.uams.edu/mirror/propred1/.
  • 75
    • 0032880649 scopus 로고    scopus 로고
    • Human tumor antigens for cancer vaccine development
    • DOI 10.1111/j.1600-065X.1999.tb01331.x
    • Wang RF, Rosenberg SA. Human tumor antigens for cancer vaccine development. Immunol Rev. 1999;170:85-100. (Pubitemid 29490747)
    • (1999) Immunological Reviews , vol.170 , pp. 85-100
    • Wang, R.-F.1    Rosenberg, S.A.2
  • 76
    • 0036583329 scopus 로고    scopus 로고
    • Ins and outs of clinical trials with peptide-based vaccines
    • Salit RB, Kast WM, Velders MP. Ins and outs of clinical trials with peptide-based vaccines. Front Biosci. 2002;7:e204-13.
    • (2002) Front Biosci , vol.7
    • Salit, R.B.1    Kast, W.M.2    Velders, M.P.3
  • 77
    • 33646480406 scopus 로고    scopus 로고
    • In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles
    • Reddy ST, Rehor A, Schmoekel HG, Hubbell JA, Swartz MA. In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles. J Control Release. 2006;112:26-34.
    • (2006) J Control Release , vol.112 , pp. 26-34
    • Reddy, S.T.1    Rehor, A.2    Schmoekel, H.G.3    Hubbell, J.A.4    Swartz, M.A.5
  • 79
    • 45149125881 scopus 로고    scopus 로고
    • Design opportunities for actively targeted nanoparticle vaccines
    • DOI 10.2217/17435889.3.3.343
    • Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond). 2008;3:343-55. (Pubitemid 351827311)
    • (2008) Nanomedicine , vol.3 , Issue.3 , pp. 343-355
    • Fahmy, T.M.1    Demento, S.L.2    Caplan, M.J.3    Mellman, I.4    Saltzman, W.M.5
  • 80
    • 2942562255 scopus 로고    scopus 로고
    • Characterization of poly(D,L-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells
    • DOI 10.1016/j.vaccine.2003.12.032, PII S0264410X0400249X, Modern Vaccine Adjuvants and Delivery Systems
    • Elamanchili P, Diwan M, Cao M, Samuel J. Characterization of poly(D, L-lactic-co-glycolic acid) based nanoparticulate system for enhanced delivery of antigens to dendritic cells. Vaccine. 2004;22:2406-12. (Pubitemid 38757337)
    • (2004) Vaccine , vol.22 , Issue.19 , pp. 2406-2412
    • Elamanchili, P.1    Diwan, M.2    Cao, M.3    Samuel, J.4
  • 81
    • 50549086919 scopus 로고    scopus 로고
    • Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cellmediated anti-tumor immunity
    • Hamdy S,MolaviO,MaZ,HaddadiA,AlshamsanA, GobtiZ, et al. Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cellmediated anti-tumor immunity. Vaccine. 2008;26:5046-57.
    • (2008) Vaccine , vol.26 , pp. 5046-5057
    • Hamdy, S.1    Molavi, O.2    Ma, Z.3    Haddadi, A.4    Alshamsan, A.5    Gobti, Z.6
  • 82
    • 33749446992 scopus 로고    scopus 로고
    • Nano- and microparticles as adjuvants in vaccine design: Success and failure is related to host natural antibodies
    • DOI 10.1016/j.vaccine.2006.06.021, PII S0264410X06007468
    • Sinyakov MS, Dror M, Lublin-Tennenbaum T, Salzberg S, Margel S, Avtalion RR. Nano- and microparticles as adjuvants in vaccine design: success and failure is related to host natural antibodies. Vaccine. 2006;24:6534-41. (Pubitemid 44511861)
    • (2006) Vaccine , vol.24 , Issue.42-43 , pp. 6534-6541
    • Sinyakov, M.S.1    Dror, M.2    Lublin-Tennenbaum, T.3    Salzberg, S.4    Margel, S.5    Avtalion, R.R.6
  • 83
    • 53549093571 scopus 로고    scopus 로고
    • Antitumor effect of all-trans retinoic acid-encapsulated nanoparticles of methoxy poly(ethylene glycol)-conjugated chitosan against CT-26 colon carcinoma in vitro
    • Park JS, Koh YS, Bang JY, Jeong YI, Lee JJ. Antitumor effect of all-trans retinoic acid-encapsulated nanoparticles of methoxy poly(ethylene glycol)-conjugated chitosan against CT-26 colon carcinoma in vitro. J Pharm Sci. 2008;97:4011-9.
    • (2008) J Pharm Sci , vol.97 , pp. 4011-4019
    • Park, J.S.1    Koh, Y.S.2    Bang, J.Y.3    Jeong, Y.I.4    Lee, J.J.5
  • 84
    • 39249084875 scopus 로고    scopus 로고
    • Nanoparticles built by self-assembly of amphiphilic gamma-PGA can deliver antigens to antigen-presenting cells with high efficiency: A new tumor-vaccine carrier for eliciting effector T cells
    • Yoshikawa T, Okada N, Oda A, Matsuo K, Matsuo K, Kayamuro H, et al. Nanoparticles built by self-assembly of amphiphilic gamma-PGA can deliver antigens to antigen-presenting cells with high efficiency: a new tumor-vaccine carrier for eliciting effector T cells. Vaccine. 2008;26:1303-13.
    • (2008) Vaccine , vol.26 , pp. 1303-1313
    • Yoshikawa, T.1    Okada, N.2    Oda, A.3    Matsuo, K.4    Matsuo, K.5    Kayamuro, H.6
  • 85
    • 77950508445 scopus 로고    scopus 로고
    • EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor
    • Yamaguchi S, Tatsumi T, Takehara T, Sasakawa A, Yamamoto M, Kohga K, et al. EphA2-derived peptide vaccine with amphiphilic poly(gamma-glutamic acid) nanoparticles elicits an anti-tumor effect against mouse liver tumor. Cancer Immunol Immunother. 2010;59:759-67.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 759-767
    • Yamaguchi, S.1    Tatsumi, T.2    Takehara, T.3    Sasakawa, A.4    Yamamoto, M.5    Kohga, K.6
  • 86
    • 0034331218 scopus 로고    scopus 로고
    • Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
    • Brossart P, Wirths S, Stuhler G, Reichardt VL, Kanz L, Brugger W. Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells. Blood. 2000;96:3102-8.
    • (2000) Blood , vol.96 , pp. 3102-3108
    • Brossart, P.1    Wirths, S.2    Stuhler, G.3    Reichardt, V.L.4    Kanz, L.5    Brugger, W.6
  • 87
    • 0036896225 scopus 로고    scopus 로고
    • Immunization with Epstein-Barr Virus (EBV) peptide-pulsed dendritic cells induces functional CD8+ T-cell immunity and may lead to tumor regression in patients with EBV-positive nasopharyngeal carcinoma
    • Lin CL, Lo WF, Lee TH, Ren Y, Hwang SL, Cheng YF, et al. Immunization with Epstein-Barr Virus (EBV) peptide-pulsed dendritic cells induces functional CD8+ T-cell immunity and may lead to tumor regression in patients with EBV-positive nasopharyngeal carcinoma. Cancer Res. 2002;62:6952-8. (Pubitemid 35424086)
    • (2002) Cancer Research , vol.62 , Issue.23 , pp. 6952-6958
    • Lin, C.-L.1    Lo, W.-F.2    Lee, T.-H.3    Ren, Y.4    Hwang, S.-L.5    Cheng, Y.-F.6    Chen, C.-L.7    Chang, Y.-S.8    Lee, S.P.9    Rickinson, A.B.10    Tam, P.K.H.11
  • 89
    • 34547843475 scopus 로고    scopus 로고
    • Opportunities to improve the prevention and treatment of cervical cancer
    • DOI 10.2174/156652407781387127
    • Roden RB, Monie A, Wu TC. Opportunities to improve the prevention and treatment of cervical cancer. Curr Mol Med. 2007;7:490-503. (Pubitemid 47244894)
    • (2007) Current Molecular Medicine , vol.7 , Issue.5 , pp. 490-503
    • Roden, R.B.S.1    Monie, A.2    Wu, T.-C.3
  • 90
    • 49749110778 scopus 로고    scopus 로고
    • A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection
    • Chua BY, Eriksson EM, Brown LE, ZengW, Gowans EJ, Torresi J, et al. A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection. Vaccine. 2008;26:4866-75.
    • (2008) Vaccine , vol.26 , pp. 4866-4875
    • Chua, B.Y.1    Eriksson, E.M.2    Brown, L.E.3    Zeng, W.4    Gowans, E.J.5    Torresi, J.6
  • 91
    • 0036839103 scopus 로고    scopus 로고
    • Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines
    • Zeng W, Ghosh S, Lau YF, Brown LE, Jackson DC. Highly immunogenic and totally synthetic lipopeptides as self-adjuvanting immunocontraceptive vaccines. J Immunol. 2002;169:4905-12. (Pubitemid 35217155)
    • (2002) Journal of Immunology , vol.169 , Issue.9 , pp. 4905-4912
    • Zeng, W.1    Ghosh, S.2    Lau, Y.F.3    Brown, L.E.4    Jackson, D.C.5
  • 93
    • 71749118913 scopus 로고    scopus 로고
    • Recognition of lipopeptide patterns by Toll-like receptor 2-Tolllike receptor 6 heterodimer
    • Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S, et al. Recognition of lipopeptide patterns by Toll-like receptor 2-Tolllike receptor 6 heterodimer. Immunity. 2009;31:873-84.
    • (2009) Immunity , vol.31 , pp. 873-884
    • Kang, J.Y.1    Nan, X.2    Jin, M.S.3    Youn, S.J.4    Ryu, Y.H.5    Mah, S.6
  • 95
    • 34247588705 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte response induced by an improved synthetic lipopeptide vaccine against cervical cancer
    • Xu DH, Zhou CH, Xia YP, Qiu ZY, Wu YZ, Jia ZC, et al. Cytotoxic T lymphocyte response induced by an improved synthetic lipopeptide vaccine against cervical cancer. Acta Pharmacol Sin. 2007;28:695-702.
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 695-702
    • Xu, D.H.1    Zhou, C.H.2    Xia, Y.P.3    Qiu, Z.Y.4    Wu, Y.Z.5    Jia, Z.C.6
  • 97
    • 0026579897 scopus 로고
    • Genetic immunization is a simple method for eliciting an immune response
    • Tang DC, DeVit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature. 1992;356:152-4.
    • (1992) Nature , vol.356 , pp. 152-154
    • Tang, D.C.1    DeVit, M.2    Johnston, S.A.3
  • 99
    • 0037388738 scopus 로고    scopus 로고
    • DNA vaccines: A review
    • DOI 10.1046/j.1365-2796.2003.01140.x
    • Liu MA. DNA vaccines: a review. J Intern Med. 2003;253:402-10. (Pubitemid 36418924)
    • (2003) Journal of Internal Medicine , vol.253 , Issue.4 , pp. 402-410
    • Liu, M.A.1
  • 100
    • 0034703836 scopus 로고    scopus 로고
    • Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine
    • Roy MJ, Wu MS, Barr LJ, Fuller JT, Tussey LG, Speller S, et al. Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine. Vaccine. 2000;19:764-78.
    • (2000) Vaccine , vol.19 , pp. 764-778
    • Roy, M.J.1    Wu, M.S.2    Barr, L.J.3    Fuller, J.T.4    Tussey, L.G.5    Speller, S.6
  • 101
    • 0029789751 scopus 로고    scopus 로고
    • Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: Antigen presentation by non-muscle cells
    • Ulmer JB, Deck RR, Dewitt CM, Donnhly JI, Liu MA. Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells. Immunology. 1996;89:59-67. (Pubitemid 26284039)
    • (1996) Immunology , vol.89 , Issue.1 , pp. 59-67
    • Ulmer, J.B.1    Deck, R.R.2    Dewitt, C.M.3    Donnelly, J.J.4    Liu, M.A.5
  • 102
    • 0033864179 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor priming plus papillomavirus E6 DNA vaccination: Effects on papilloma formation and regression in the cottontail rabbit papillomavirus-rabbit model
    • DOI 10.1128/JVI.74.18.8700-8708.2000
    • Leachman SA, Tigelaar RE, Shlyankevich M, Slade MD, Irwin M, Chang E, et al. Granulocyte-macrophage colony-stimulating factor priming plus papillomavirus E6 DNA vaccination: effects on papilloma formation and regression in the cottontail rabbit papillomavirus-rabbit model. J Virol. 2000;74:8700-8. (Pubitemid 30666720)
    • (2000) Journal of Virology , vol.74 , Issue.18 , pp. 8700-8708
    • Leachman, S.A.1    Tigelaar, R.E.2    Shlyankevich, M.3    Slade, M.D.4    Irwin, M.5    Chang, E.6    Wu, T.C.7    Xiao, W.8    Pazhani, S.9    Zelterman, D.10    Brandsma, J.L.11
  • 103
    • 0032958073 scopus 로고    scopus 로고
    • Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
    • DOI 10.1038/7385
    • Roy K, Mao HQ, Huang SK, Leong KW. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat Med. 1999;5:387-91. (Pubitemid 29180575)
    • (1999) Nature Medicine , vol.5 , Issue.4 , pp. 387-391
    • Roy, K.1    Mao, H.-Q.2    Huang, S.-K.3    Leong, K.W.4
  • 104
    • 0034788572 scopus 로고    scopus 로고
    • Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen
    • DOI 10.1172/JCI200112346
    • Cheng WF, Hung CF, Chai CY, Hsu KF, He L, Ling M, et al. Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen. J Clin Invest. 2001;108:669-78. (Pubitemid 32906195)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.5 , pp. 669-678
    • Cheng, W.-F.1    Hung, C.-F.2    Chai, C.-Y.3    Hsu, K.-F.4    He, L.5    Ling, M.6    Wu, T.-C.7
  • 105
    • 33645105886 scopus 로고    scopus 로고
    • Cancer immunotherapy using dendritic/tumour-fusion vaccine induces elevation of serum anti-nuclear antibody with better clinical responses
    • Homma S, Sagawa Y, Ito M, Ohno T, Toda G. Cancer immunotherapy using dendritic/tumour-fusion vaccine induces elevation of serum anti-nuclear antibody with better clinical responses. Clin Exp Immunol. 2006;144:41-7.
    • (2006) Clin Exp Immunol , vol.144 , pp. 41-47
    • Homma, S.1    Sagawa, Y.2    Ito, M.3    Ohno, T.4    Toda, G.5
  • 107
    • 0037689451 scopus 로고    scopus 로고
    • Induction of specific antitumor immunity in the mouse with the electrofusion product of tumor cells and dendritic cells
    • DOI 10.1016/S1525-0016(03)00044-3
    • Siders WM, Vergilis KL, Johnson C, Shields J, Kaplan JM. Induction of specific antitumor immunity in the mouse with the electrofusion product of tumor cells and dendritic cells. Mol Ther. 2003;7:498-505. (Pubitemid 36553419)
    • (2003) Molecular Therapy , vol.7 , Issue.4 , pp. 498-505
    • Siders, W.M.1    Vergilis, K.L.2    Johnson, C.3    Shields, J.4    Kaplan, J.M.5
  • 109
    • 0242373834 scopus 로고    scopus 로고
    • In vivo induction of dendritic cell-mediated cytotoxicity against allogeneic pancreatic carcinoma cells
    • Stift A, Friedl J, Dubsky P, Bachleitner-Hofmann T, Benkoe T, Brostjan C, et al. In vivo induction of dendritic cell-mediated cytotoxicity against allogeneic pancreatic carcinoma cells. Int J Oncol. 2003;22:651-6.
    • (2003) Int J Oncol , vol.22 , pp. 651-656
    • Stift, A.1    Friedl, J.2    Dubsky, P.3    Bachleitner-Hofmann, T.4    Benkoe, T.5    Brostjan, C.6
  • 110
    • 33645325115 scopus 로고    scopus 로고
    • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized phase III trial of the DC study group of the DeCOG
    • Schadendorf D, Ugurel S, Schuler-Thurner B, Nestle FO, Enk A, Brocker EB, et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG. Ann Oncol. 2006;17:563-70.
    • (2006) Ann Oncol , vol.17 , pp. 563-570
    • Schadendorf, D.1    Ugurel, S.2    Schuler-Thurner, B.3    Nestle, F.O.4    Enk, A.5    Brocker, E.B.6
  • 111
    • 29444443970 scopus 로고    scopus 로고
    • In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles
    • Kwon YJ, James E, Shastri N, Frechet JM. In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticles. Proc Natl Acad Sci USA. 2005;102:18264-8.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18264-18268
    • Kwon, Y.J.1    James, E.2    Shastri, N.3    Frechet, J.M.4
  • 112
    • 34247569871 scopus 로고    scopus 로고
    • "Pathogen-mimicking" nanoparticles for vaccine delivery to dendritic cells
    • Elamanchili P, Lutsiak CM, Hamdy S, Diwan M, Samuel J. "Pathogen-mimicking" nanoparticles for vaccine delivery to dendritic cells. J Immunother. 2007;30:378-95.
    • (2007) J Immunother , vol.30 , pp. 378-395
    • Elamanchili, P.1    Lutsiak, C.M.2    Hamdy, S.3    Diwan, M.4    Samuel, J.5
  • 114
    • 0025834747 scopus 로고
    • Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies
    • Eldridge JH, Staas JK, Meulbroek JA, Tice TR, Gilley RM. Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect Immun. 1991;59:2978-86.
    • (1991) Infect Immun , vol.59 , pp. 2978-2986
    • Eldridge, J.H.1    Staas, J.K.2    Meulbroek, J.A.3    Tice, T.R.4    Gilley, R.M.5
  • 115
    • 0026497688 scopus 로고
    • Evaluation of biodegradable microspheres as vaccine adjuvant for hepatitis B surface antigen
    • Nellore RV, Pande PG, Young D, Bhagat HR. Evaluation of biodegradable microspheres as vaccine adjuvant for hepatitis B surface antigen. J Parenter Sci Technol. 1992;46:176-80.
    • (1992) J Parenter Sci Technol , vol.46 , pp. 176-180
    • Nellore, R.V.1    Pande, P.G.2    Young, D.3    Bhagat, H.R.4
  • 116
    • 0030952306 scopus 로고    scopus 로고
    • Immunogenicity and protection in small-animal models with controlled- Release tetanus toxoid microparticles as a single-dose vaccine
    • Singh M, Li XM, Wang H, McGee JP, Zamb T, Koff W, et al. Immunogenicity and protection in small-animal models with controlled-release tetanus toxoid microparticles as a single-dose vaccine. Infect Immun. 1997;65:1716-21. (Pubitemid 27193591)
    • (1997) Infection and Immunity , vol.65 , Issue.5 , pp. 1716-1721
    • Singh, M.1    Li, X.-M.2    Wang, H.3    McGee, J.P.4    Zamb, T.5    Koff, W.6    Wang, C.Y.7    O'Hagan, D.T.8
  • 117
    • 0031765186 scopus 로고    scopus 로고
    • Delivery of MUC1 mucin peptide by Poly(d, l-lactic-co-glycolic acid) microspheres induces type 1 T helper immune responses
    • Newman KD, Sosnowski DL, Kwon GS, Samuel J. Delivery of MUC1 mucin peptide by Poly(d, l-lactic-co-glycolic acid) microspheres induces type 1 T helper immune responses. J Pharm Sci. 1998;87:1421-7.
    • (1998) J Pharm Sci , vol.87 , pp. 1421-1427
    • Newman, K.D.1    Sosnowski, D.L.2    Kwon, G.S.3    Samuel, J.4
  • 118
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm. 2008;5:496-504.
    • (2008) Mol Pharm , vol.5 , pp. 496-504
    • Li, S.D.1    Huang, L.2
  • 119
    • 0026571235 scopus 로고
    • MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo
    • Grant EP, Rock KL. MHC class I-restricted presentation of exogenous antigen by thymic antigen-presenting cells in vitro and in vivo. J Immunol. 1992;148:13-8.
    • (1992) J Immunol , vol.148 , pp. 13-18
    • Grant, E.P.1    Rock, K.L.2
  • 120
    • 0016294470 scopus 로고
    • Morphological observations on the cellular and subcellular destination of intravenously administered liposomes
    • Segal AW, Wills EJ, Richmond JE, Slavin G, Black CD, Gregoriadis G. Morphological observations on the cellular and subcellular destination of intravenously administered liposomes. Br J Exp Pathol. 1974;55:320-7.
    • (1974) Br J Exp Pathol , vol.55 , pp. 320-327
    • Segal, A.W.1    Wills, E.J.2    Richmond, J.E.3    Slavin, G.4    Black, C.D.5    Gregoriadis, G.6
  • 121
    • 38649109511 scopus 로고    scopus 로고
    • A simple but effective cancer vaccine consisting of an antigen and a cationic lipid
    • DOI 10.1007/s00262-007-0390-4
    • Chen W, Yan W, Huang L. A simple but effective cancer vaccine consisting of an antigen and a cationic lipid. Cancer Immunol Immunother. 2008;57:517-30. (Pubitemid 351170535)
    • (2008) Cancer Immunology, Immunotherapy , vol.57 , Issue.4 , pp. 517-530
    • Chen, W.1    Yan, W.2    Huang, L.3
  • 122
    • 0343938832 scopus 로고    scopus 로고
    • Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells
    • DOI 10.1016/S0169-409X(99)00064-2, PII S0169409X99000642
    • Rao M, Alving CR. Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells. mangala. rao@na.amedd.army.mil. Adv Drug Deliv Rev. 2000;41:171-88. (Pubitemid 30122957)
    • (2000) Advanced Drug Delivery Reviews , vol.41 , Issue.2 , pp. 171-188
    • Rao, M.1    Alving, C.R.2
  • 123
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang AY, Golumbek P, Ahmadzadeh M, Jaffee E, Pardoll D, Levitsky H. Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science. 1994;264:961-5. (Pubitemid 24196166)
    • (1994) Science , vol.264 , Issue.5161 , pp. 961-965
    • Huang, A.Y.C.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 124
    • 0029162385 scopus 로고
    • Antigen presentation to cytotoxic T lymphocytes in vivo
    • Bevan MJ. Antigen presentation to cytotoxic T lymphocytes in vivo. J Exp Med. 1995;182:639-41.
    • (1995) J Exp Med , vol.182 , pp. 639-641
    • Bevan, M.J.1
  • 125
    • 3042809887 scopus 로고    scopus 로고
    • Coating of mannan on LPD particles containing HPV E7 peptide significantly enhances immunity against HPV-positive tumor
    • DOI 10.1023/B:PHAM.0000029292.66792.4f
    • Cui Z, Han SJ, Huang L. Coating of mannan on LPD particles containing HPV E7 peptide significantly enhances immunity against HPV-positive tumor. Pharm Res. 2004;21:1018-25. (Pubitemid 38870153)
    • (2004) Pharmaceutical Research , vol.21 , Issue.6 , pp. 1018-1025
    • Cui, Z.1    Han, S.-J.2    Huang, L.3
  • 126
    • 26244465082 scopus 로고    scopus 로고
    • Liposome-polycation-DNA (LPD) particle as a carrier and adjuvant for protein-based vaccines: Therapeutic effect against cervical cancer
    • DOI 10.1007/s00262-005-0685-2
    • Cui Z, Huang L. Liposome-polycation-DNA (LPD) particle as a carrier and adjuvant for protein-based vaccines: therapeutic effect against cervical cancer. Cancer Immunol Immunother. 2005;54:1180-90. (Pubitemid 41416950)
    • (2005) Cancer Immunology, Immunotherapy , vol.54 , Issue.12 , pp. 1180-1190
    • Cui, Z.1    Huang, L.2
  • 127
    • 0026732781 scopus 로고
    • Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway
    • Walker C, Selby M, Erickson A, Cataldo D, Valensi JP, Van Nest GV. Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway. Proc Natl Acad Sci USA. 1992;89:7915-8.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7915-7918
    • Walker, C.1    Selby, M.2    Erickson, A.3    Cataldo, D.4    Valensi, J.P.5    Van Nest, G.V.6
  • 128
    • 0027462372 scopus 로고
    • Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway. Priming in vitro and in vivo for class I-restricted recognition of soluble antigen
    • Chen W, Carbone FR, McCluskey J. Electroporation and commercial liposomes efficiently deliver soluble protein into the MHC class I presentation pathway. Priming in vitro and in vivo for class I-restricted recognition of soluble antigen. J Immunol Methods. 1993;160:49-57.
    • (1993) J Immunol Methods , vol.160 , pp. 49-57
    • Chen, W.1    Carbone, F.R.2    McCluskey, J.3
  • 129
    • 0035988756 scopus 로고    scopus 로고
    • LPD nanoparticles-novel nonviral vector for efficient gene delivery
    • Tan Y, Whitmore M, Li S, Frederik P, Huang L. LPD nanoparticles-novel nonviral vector for efficient gene delivery. Methods Mol Med. 2002;69:73-81.
    • (2002) Methods Mol Med , vol.69 , pp. 73-81
    • Tan, Y.1    Whitmore, M.2    Li, S.3    Frederik, P.4    Huang, L.5
  • 130
    • 0030038942 scopus 로고    scopus 로고
    • Potentiation of cationic liposome-mediated gene delivery by polycations
    • DOI 10.1021/bi952436a
    • Gao X, Huang L. Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry. 1996;35:1027-36. (Pubitemid 26034590)
    • (1996) Biochemistry , vol.35 , Issue.3 , pp. 1027-1036
    • Gao, X.1    Huang, L.2
  • 131
    • 0030866645 scopus 로고    scopus 로고
    • In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes
    • Li S, Huang L. In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther. 1997;4:891-900.
    • (1997) Gene Ther , vol.4 , pp. 891-900
    • Li, S.1    Huang, L.2
  • 132
    • 0033199598 scopus 로고    scopus 로고
    • The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo
    • DOI 10.1089/10430349950017149
    • Tan Y, Li S, Pitt BR, Huang L. The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Hum Gene Ther. 1999;10:2153-61. (Pubitemid 29416295)
    • (1999) Human Gene Therapy , vol.10 , Issue.13 , pp. 2153-2161
    • Tan, Y.1    Li, S.2    Pitt, B.R.3    Huang, L.4
  • 133
    • 0038529616 scopus 로고    scopus 로고
    • Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses
    • DOI 10.1016/S1525-0016(03)00064-9
    • Dileo J, Banerjee R, Whitmore M, Nayak JV, Falo Jr LD, Huang L. Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses. Mol Ther. 2003;7:640-8. (Pubitemid 36626244)
    • (2003) Molecular Therapy , vol.7 , Issue.5 I , pp. 640-648
    • Dileo, J.1    Banerjee, R.2    Whitmore, M.3    Nayak, J.V.4    Falo Jr., L.D.5    Huang, L.6
  • 136
    • 0034991899 scopus 로고    scopus 로고
    • Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity
    • DOI 10.1006/mthe.2001.0311
    • Tan Y, Liu F, Li Z, Li S, Huang L. Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity. Mol Ther. 2001;3:673-82. (Pubitemid 32509864)
    • (2001) Molecular Therapy , vol.3 , Issue.5 I , pp. 673-682
    • Tan, Y.1    Liu, F.2    Li, Z.3    Li, S.4    Huang, L.5
  • 137
    • 48449089960 scopus 로고    scopus 로고
    • Recent developments in leishmaniasis vaccine delivery systems
    • Bhowmick S, Ali N. Recent developments in leishmaniasis vaccine delivery systems. Expert Opin Drug Deliv. 2008;5:789-803.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 789-803
    • Bhowmick, S.1    Ali, N.2
  • 138
    • 44049096331 scopus 로고    scopus 로고
    • Liposome vectors for in vivo gene delivery
    • Chapter 12:Unit 12.8
    • Whitemore M, Li S, Huang L. Liposome vectors for in vivo gene delivery. Curr Protoc Hum Genet. Chapter 12:Unit 12.8 (2001).
    • (2001) Curr Protoc Hum Genet
    • Whitemore, M.1    Li, S.2    Huang, L.3
  • 139
    • 34249291291 scopus 로고    scopus 로고
    • Mechanism of adjuvant activity of cationic liposome: Phosphorylation of a MAP kinase, ERK and induction of chemokines
    • Yan W, Chen W, Huang L. Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokines. Mol Immunol. 2007;44:3672-81.
    • (2007) Mol Immunol , vol.44 , pp. 3672-3681
    • Yan, W.1    Chen, W.2    Huang, L.3
  • 141
    • 54049133721 scopus 로고    scopus 로고
    • Delivery strategies of melanoma vaccines: An overview
    • Lai YH, Wang C. Delivery strategies of melanoma vaccines: an overview. Expert Opin Drug Deliv. 2008;5:979-1001.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 979-1001
    • Lai, Y.H.1    Wang, C.2
  • 142
    • 0035940317 scopus 로고    scopus 로고
    • Manipulating the immune system: Humoral versus cell-mediated immunity
    • DOI 10.1016/S0169-409X(01)00169-7, PII S0169409X01001697
    • McNeela EA, Mills KH. Manipulating the immune system: humoral versus cell-mediated immunity. Adv Drug Deliv Rev. 2001;51:43-54. (Pubitemid 32763071)
    • (2001) Advanced Drug Delivery Reviews , vol.51 , Issue.1-3 , pp. 43-54
    • McNeela, E.A.1    Mills, K.H.G.2
  • 143
    • 67349269509 scopus 로고    scopus 로고
    • Mechanism of action of licensed vaccine adjuvants
    • Tritto E, Mosca F, De GE. Mechanism of action of licensed vaccine adjuvants. Vaccine. 2009;27:3331-4.
    • (2009) Vaccine , vol.27 , pp. 3331-3334
    • Tritto, E.1    Mosca, F.2    De, G.E.3
  • 144
    • 0035925666 scopus 로고    scopus 로고
    • The adjuvanted influenza vaccines with novel adjuvants: Experience with the MF59-adjuvanted vaccine
    • DOI 10.1016/S0264-410X(00)00499-0, PII S0264410X00004990
    • Podda A. The adjuvanted influenza vaccines with novel adjuvants: experience with the MF59-adjuvanted vaccine. Vaccine. 2001;19:2673-80. (Pubitemid 32234288)
    • (2001) Vaccine , vol.19 , Issue.17-19 , pp. 2673-2680
    • Podda, A.1
  • 145
    • 34250800861 scopus 로고    scopus 로고
    • Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients
    • DOI 10.1002/cncr.22739
    • Armstrong JK, Hempel G, Koling S, Chan LS, Fisher T, Meiselman HJ, et al. Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients. Cancer. 2007;110:103-11. (Pubitemid 46986423)
    • (2007) Cancer , vol.110 , Issue.1 , pp. 103-111
    • Armstrong, J.K.1    Hempel, G.2    Koling, S.3    Chan, L.S.4    Fisher, T.5    Meiselman, H.J.6    Garratty, G.7
  • 146
    • 33748501472 scopus 로고    scopus 로고
    • Antibodies to lipids and liposomes: Immunology and safety
    • DOI 10.1080/08982100600848553, PII G1N7974081P75747
    • Alving CR. Antibodies to lipids and liposomes: immunology and safety. J Liposome Res. 2006;16:157-66. (Pubitemid 44358989)
    • (2006) Journal of Liposome Research , vol.16 , Issue.3 , pp. 157-166
    • Alving, C.R.1
  • 150
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • Machiels JP, Reilly RT, Emens LA, Ercolini AM, Lei RY, Weintraub D, et al. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/ macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res. 2001;61:3689-97. (Pubitemid 32694981)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3689-3697
    • Machiels, J.-P.H.1    Todd, R.R.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5    Weintraub, D.6    Okoye, F.I.7    Jaffee, E.M.8
  • 152
    • 49249127841 scopus 로고    scopus 로고
    • Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies
    • Apetoh L, Tesniere A, Ghiringhelli F, Kroemer G, Zitvogel L. Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies. Cancer Res. 2008;68:4026-30.
    • (2008) Cancer Res , vol.68 , pp. 4026-4030
    • Apetoh, L.1    Tesniere, A.2    Ghiringhelli, F.3    Kroemer, G.4    Zitvogel, L.5
  • 153
    • 68349123372 scopus 로고    scopus 로고
    • Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism
    • Shurin GV, Tourkova IL, Kaneno R, Shurin MR. Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12-dependent mechanism. J Immunol. 2009;183:137-44.
    • (2009) J Immunol , vol.183 , pp. 137-144
    • Shurin, G.V.1    Tourkova, I.L.2    Kaneno, R.3    Shurin, M.R.4
  • 154
    • 70350108862 scopus 로고    scopus 로고
    • Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination
    • Radojcic V, Bezak KB, Skarica M, Pletneva MA, Yoshimura K, Schulick RD, et al. Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination. Cancer Immunol Immunother. 2010;59:137-48.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 137-148
    • Radojcic, V.1    Bezak, K.B.2    Skarica, M.3    Pletneva, M.A.4    Yoshimura, K.5    Schulick, R.D.6
  • 156
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • DOI 10.1084/jem.155.4.1063
    • North RJ. Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J Exp Med. 1982;155:1063-74. (Pubitemid 12142723)
    • (1982) Journal of Experimental Medicine , vol.155 , Issue.4 , pp. 1063-1074
    • North, R.J.1
  • 157
    • 57649136406 scopus 로고    scopus 로고
    • Nanotechnology approaches to crossing the bloodbrain barrier and drug delivery to the CNS
    • Silva GA. Nanotechnology approaches to crossing the bloodbrain barrier and drug delivery to the CNS. BMC Neurosci. 2008;9 Suppl 3:S4.
    • (2008) BMC Neurosci , vol.9 , Issue.SUPPL. 3
    • Silva, G.A.1
  • 158
    • 27944486495 scopus 로고    scopus 로고
    • Cancer immunotherapy based on intracellular hyperthermia using magnetite nanoparticles: A novel concept of "heat-controlled necrosis" with heat shock protein expression
    • Ito A, Honda H, Kobayashi T. Cancer immunotherapy based on intracellular hyperthermia using magnetite nanoparticles: a novel concept of "heat-controlled necrosis" with heat shock protein expression. Cancer Immunol Immunother. 2006;55:320-8.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 320-328
    • Ito, A.1    Honda, H.2    Kobayashi, T.3
  • 160
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • Maeda H. The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul. 2001;41:189-207.
    • (2001) Adv Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 161
    • 0030044935 scopus 로고    scopus 로고
    • Drug targeting in cancer therapy: The magic bullet, what next?
    • Duncan R, Connors TA, Meada H. Drug targeting in cancer therapy: the magic bullet, what next? J Drug Target. 1996;3:317-9. (Pubitemid 26059822)
    • (1996) Journal of Drug Targeting , vol.3 , Issue.5 , pp. 317-319
    • Duncan, R.1    Connors, T.A.2    Meada, H.3
  • 162
    • 0032489812 scopus 로고    scopus 로고
    • Targeted delivery of chemotherapeutics: Tumor-activated prodrug therapy
    • DOI 10.1016/S0169-409X(97)00095-1, PII S0169409X97000951
    • Chari RV. Targeted delivery of chemotherapeutics: tumor-activated prodrug therapy. Adv Drug Deliv Rev. 1998;31:89-104. (Pubitemid 28191877)
    • (1998) Advanced Drug Delivery Reviews , vol.31 , Issue.1-2 , pp. 89-104
    • Chari, R.V.J.1
  • 163
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • DOI 10.1016/S0168-3659(99)00248-5, PII S0168365999002485
    • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release. 2000;65:271-84. (Pubitemid 30122932)
    • (2000) Journal of Controlled Release , vol.65 , Issue.1-2 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.