-
1
-
-
9644275599
-
Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis
-
Kim B, Tang Q, Biswas PS, Xu J, Schliffelers RM, Xie FY et al. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol 2004; 165: 2177-2185. (Pubitemid 39578394)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.6
, pp. 2177-2185
-
-
Kim, B.1
Tang, Q.2
Biswas, P.S.3
Xu, J.4
Schiffelers, R.M.5
Xie, F.Y.6
Ansari, A.M.7
Scaria, P.V.8
Woodle, M.C.9
Lu, P.10
Rouse, B.T.11
-
2
-
-
46449086130
-
Capped small RNAs and MOV10 in human hepatitis delta virus replication
-
DOI 10.1038/nsmb.1440, PII NSMB1440
-
Haussecker D, Cao D, Huang Y, Parameswaran P, Fire AZ, Kay MA. Capped small RNAs and MOV10 in human hepatitis delta virus replication. Nat Struct Mol Biol 2008; 15: 714-721. (Pubitemid 351932001)
-
(2008)
Nature Structural and Molecular Biology
, vol.15
, Issue.7
, pp. 714-721
-
-
Haussecker, D.1
Cao, D.2
Huang, Y.3
Parameswaran, P.4
Fire, A.Z.5
Kay, M.A.6
-
3
-
-
0037213559
-
Mammalian RNAi for the masses
-
DOI 10.1016/S0168-9525(02)00005-7, PII S0168952502000057
-
Shi Y. Mammalian RNAi for the masses. Trends Genet 2003; 19: 9-12. (Pubitemid 35472172)
-
(2003)
Trends in Genetics
, vol.19
, Issue.1
, pp. 9-12
-
-
Shi, Y.1
-
5
-
-
60149094505
-
RNA interference: From basic research to therapeutic applications
-
Kurreck J. RNA interference: from basic research to therapeutic applications. Angew Chem Int Ed Engl 2009; 48: 1378-1398.
-
(2009)
Angew Chem Int Ed Engl
, vol.48
, pp. 1378-1398
-
-
Kurreck, J.1
-
6
-
-
70350625443
-
Gene therapy deserves a fresh chance
-
Anonymous
-
Anonymous. Gene therapy deserves a fresh chance. Nature 2009; 461: 1173.
-
(2009)
Nature
, vol.461
, pp. 1173
-
-
-
7
-
-
34047107246
-
An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells
-
Ma HT, On KF, Tsang YH, Poon RY. An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells. Nucleic Acids Res 2007; 35: e22.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Ma, H.T.1
On, K.F.2
Tsang, Y.H.3
Poon, R.Y.4
-
8
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
DOI 10.1126/science.1068999
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296: 550-553. (Pubitemid 34408678)
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
9
-
-
0035933760
-
Coutelle. An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy
-
Bigger BW, Tolmachov O, Collombet JM, Fragkos M, Palaszewski I, Coutelle. An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy. J Biol Chem 2001; 276: 23018-23027.
-
(2001)
J Biol Chem
, vol.276
, pp. 23018-23027
-
-
Bigger, B.W.1
Tolmachov, O.2
Collombet, J.M.3
Fragkos, M.4
Palaszewski, I.5
-
10
-
-
0000899674
-
Enzymatic synthesis of deoxyribonucleic acid. XI. Further studies on nearest neighbor base sequences in deoxyribonucleic acids
-
Swartz MN, Trautner TA, Kornberg A. Enzymatic synthesis of deoxyribonucleic acid. XI. Further studies on nearest neighbor base sequences in deoxyribonucleic acids. J Biol Chem 1962; 237: 1961-1967.
-
(1962)
J Biol Chem
, vol.237
, pp. 1961-1967
-
-
Swartz, M.N.1
Trautner, T.A.2
Kornberg, A.3
-
11
-
-
2642519089
-
Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo
-
DOI 10.1038/sj.gt.3302231
-
Chen ZY, He CY, Meuse L, Kay MA. Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo. Gene Therapy 2004; 11: 856-864. (Pubitemid 38714589)
-
(2004)
Gene Therapy
, vol.11
, Issue.10
, pp. 856-864
-
-
Chen, Z.Y.1
He, C.Y.2
Meuse, L.3
Kay, M.A.4
-
12
-
-
0031436820
-
A new DNA vehicle for nonviral gene delivery: Supercoiled minicircle
-
Darquet AM, Cameron B, Wils P, Scherman D, Crouzet J. A new DNA vehicle for nonviral gene delivery: supercoiled minicircle. Gene Therapy 1997; 4: 1341-1349. (Pubitemid 28004593)
-
(1997)
Gene Therapy
, vol.4
, Issue.12
, pp. 1341-1349
-
-
Darquet, A.-M.1
Cameron, B.2
Wils, P.3
Scherman, D.4
Crouzet, J.5
-
13
-
-
0035989006
-
CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo
-
DOI 10.1006/mthe.2002.0598
-
Yew NS, Zhao H, Przbylska M, Wu IH, Tousignant JD, Scheule RK et al. CpG-depleted plasmid DNA vectors with enhanced safety and long-term gene expression in vivo. Mol Ther 2002; 5: 731-738. (Pubitemid 34619066)
-
(2002)
Molecular Therapy
, vol.5
, Issue.6
, pp. 731-738
-
-
Yew, N.S.1
Zhao, H.2
Przybylska, M.3
Wu, I.-H.4
Tousignant, J.D.5
Scheule, R.K.6
Cheng, S.H.7
-
14
-
-
1342332864
-
CpG methylation of a plasmid vector results in extended transgene product expression by circumventing induction of immune responses
-
DOI 10.1016/j.ymthe.2003.11.008
-
Reyes-Sandoval A, Ertl HC. CpG methylation of a plasmid vector results in extended transgene product expression by circumventing induction of immune responses. Mol Ther 2004; 9: 249-261. (Pubitemid 38256551)
-
(2004)
Molecular Therapy
, vol.9
, Issue.2
, pp. 249-261
-
-
Reyes-Sandoval, A.1
Ertl, H.C.J.2
-
15
-
-
0041315884
-
Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
-
DOI 10.1016/S1525-0016(03)00168-0
-
Chen ZY, He CY, Ehrhardt A, Kay MA. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther 2003; 8: 495-500. (Pubitemid 37161471)
-
(2003)
Molecular Therapy
, vol.8
, Issue.3
, pp. 495-500
-
-
Chen, Z.-Y.1
He, C.-Y.2
Ehrhardt, A.3
Kay, M.A.4
-
16
-
-
77449147610
-
FRT-seq: Amplification-free, strand-specific transcriptome sequencing
-
Mamanova L, Andrews RM, James KD, Sheridan EM, Ellis PD, Langford CF et al. FRT-seq: amplification-free, strand-specific transcriptome sequencing. Nat Methods 2010; 7: 130-132.
-
(2010)
Nat Methods
, vol.7
, pp. 130-132
-
-
Mamanova, L.1
Andrews, R.M.2
James, K.D.3
Sheridan, E.M.4
Ellis, P.D.5
Langford, C.F.6
-
17
-
-
0033214209
-
Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency
-
DOI 10.1093/nar/27.19.3792
-
Kreiss P, Cameron B, Rangara R, Mailhe P, Aguerre-Charriol O, Airiau M et al. Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency. Nucleic Acids Res 1999; 27: 3792-3798. (Pubitemid 29454426)
-
(1999)
Nucleic Acids Research
, vol.27
, Issue.19
, pp. 3792-3798
-
-
Kreiss, P.1
Cameron, B.2
Rangara, R.3
Mailhe, P.4
Aguerre-Charriol, O.5
Airiau, M.6
Scherman, D.7
Crouzet, J.8
Pitard, B.9
-
18
-
-
27644569313
-
Investigations of the effect of DNA size in transient transfection assay using dual luciferase system
-
DOI 10.1016/j.ab.2005.08.029, PII S0003269705006111
-
Yin W, Xiang P, Li Q. Investigations of the effect of DNA size in transient transfection assay using dual luciferase system. Anal Biochem 2005; 346: 289-294. (Pubitemid 41550259)
-
(2005)
Analytical Biochemistry
, vol.346
, Issue.2
, pp. 289-294
-
-
Yin, W.1
Xiang, P.2
Li, Q.3
-
19
-
-
33645295275
-
Exploring writhe in supercoiled minicircle DNA
-
Fogg JM, Kolmakova N, Rees I, Magonov S, Hansma H, Perona JJ et al. Exploring writhe in supercoiled minicircle DNA. J Phys Condens Matter 2006; 18: S145-S159.
-
(2006)
J Phys Condens Matter
, vol.18
-
-
Fogg, J.M.1
Kolmakova, N.2
Rees, I.3
Magonov, S.4
Hansma, H.5
Perona, J.J.6
-
20
-
-
0028049305
-
The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix. Possible implications for DNA structure in vivo
-
Bednar J, Furrer P, Stasiak A, Dubochet J, Egelman EH, Bates AD. The twist, writhe and overall shape of supercoiled DNA change during counterion-induced transition from a loosely to a tightly interwound superhelix. Possible implications for DNA structure in vivo. J Mol Biol 1994; 235: 825-847.
-
(1994)
J Mol Biol
, vol.235
, pp. 825-847
-
-
Bednar, J.1
Furrer, P.2
Stasiak, A.3
Dubochet, J.4
Egelman, E.H.5
Bates, A.D.6
-
21
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, Saltman DL et al. Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 1994; 263: 1281-1284. (Pubitemid 24107549)
-
(1994)
Science
, vol.263
, Issue.5151
, pp. 1281-1284
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
Dittmer, K.G.4
Shapiro, D.N.5
Saltman, D.L.6
Look, A.T.7
-
22
-
-
0030767794
-
The NPM/ALK gene fusion in the pathogenesis of anaplastic large cell lymphoma
-
Ladanyi M. The NPM/ALK gene fusion in the pathogenesis of anaplastic large cell lymphoma. Cancer Surv 1997; 30: 59-75. (Pubitemid 27371536)
-
(1997)
Cancer Surveys
, vol.30
, pp. 59-75
-
-
Ladanyi, M.1
-
23
-
-
30444446194
-
Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas
-
DOI 10.1182/blood-2005-05-2125
-
Piva R, Chiarle R, Manazza AD, Taulli R, Simmons W, Ambrogio C et al. Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas. Blood 2006; 107: 689-697. (Pubitemid 43076395)
-
(2006)
Blood
, vol.107
, Issue.2
, pp. 689-697
-
-
Piva, R.1
Chiarle, R.2
Manazza, A.D.3
Taulli, R.4
Simmons, W.5
Ambrogio, C.6
D'Escamard, V.7
Pellegrino, E.8
Ponzetto, C.9
Palestro, G.10
Inghirami, G.11
-
24
-
-
34948834758
-
Pathobiology of ALK+anaplastic large-cell lymphoma
-
Amin HM, Lai R. Pathobiology of ALK+anaplastic large-cell lymphoma. Blood 2007; 110: 2259-2267.
-
(2007)
Blood
, vol.110
, pp. 2259-2267
-
-
Amin, H.M.1
Lai, R.2
-
25
-
-
1642523434
-
Design and Evaluation of Chemically Synthesized siRNA Targeting the NPM-ALK Fusion Site in Anaplastic Large Cell Lymphoma (ALCL)
-
DOI 10.1089/154545703322617041
-
Ritter U, Damm-Welk C, Fuchs U, Bohle RM, Borkhardt A, Woessmann W. Design and evaluation of chemically synthesized siRNA targeting the NPM-ALK fusion site in anaplastic large cell lymphoma (ALCL). Oligonucleotides 2003; 13: 365-373. (Pubitemid 38404821)
-
(2003)
Oligonucleotides
, vol.13
, Issue.5
, pp. 365-373
-
-
Ritter, U.1
Damm-Welk, C.2
Fuchs, U.3
Bohle, R.M.4
Borkhardt, A.5
Woessmann, W.6
-
26
-
-
34347396141
-
Downregulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro
-
DOI 10.1080/07357900701206372, PII 779831627
-
Hsu FY, Zhao Y, Anderson WF, Johnston PB. Down regulation of NPM-ALK by siRNA causes anaplastic large cell lymphoma cell growth inhibition and augments the anti cancer effects of chemotherapy in vitro. Cancer Invest 2007; 25: 240-248. (Pubitemid 47026946)
-
(2007)
Cancer Investigation
, vol.25
, Issue.4
, pp. 240-248
-
-
Hsu, F.Y.-Y.1
Zhao, Y.2
Anderson, W.F.3
Johnston, P.B.4
-
27
-
-
27944485366
-
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
-
DOI 10.1038/labinvest.3700348, PII 3700348
-
Marzec M, Kasprzcka M, Ptasznik A, Wlodarski P, Zhang Q, Odum N etal. Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3. Lab Invest2005; 85: 1544-1554. (Pubitemid 41662338)
-
(2005)
Laboratory Investigation
, vol.85
, Issue.12
, pp. 1544-1554
-
-
Marzec, M.1
Kasprzycka, M.2
Ptasznik, A.3
Wlodarski, P.4
Zhang, Q.5
Odum, N.6
Wasik, M.A.7
-
28
-
-
38649100358
-
Titers of HIV-based vectors encoding shRNAs are reduced by a dicer-dependent mechanism
-
DOI 10.1038/sj.mt.6300370, PII 6300370
-
Poluri A, Sutton RE. Titers of HIV-based vectors encoding shRNAs are reduced by a dicer-dependent mechanism. Mol Ther 2008; 16: 378-386. (Pubitemid 351168047)
-
(2008)
Molecular Therapy
, vol.16
, Issue.2
, pp. 378-386
-
-
Poluri, A.1
Sutton, R.E.2
-
29
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
DOI 10.1073/pnas.0437912100
-
Tiscornia G, Singer O, Ikawa M, Verma IM. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci USA 2003; 100: 1844-1848. (Pubitemid 36254536)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.4
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
30
-
-
77955920848
-
Synergistic inhibition of anaplastic large cell lymphoma cells by combining cellular ALK gene silencing and a low dose of the kinase inhibitor U0126
-
Ito M, Zhao N, Zeng Z, Chang CC, Zu Y Synergistic inhibition of anaplastic large cell lymphoma cells by combining cellular ALK gene silencing and a low dose of the kinase inhibitor U0126. Cancer Gene Ther 2010; 17: 633-644.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 633-644
-
-
Ito, M.1
Zhao, N.2
Zeng, Z.3
Chang, C.C.4
Zu, Y.5
-
31
-
-
0030771373
-
Topoisomerase IV, not gyrase, decatenates products of site-specific recombination in Escherichia coli
-
Zechiedrich EL, Khodursky AB, Cozzarelli NR. Topoisomerase IV, not gyrase, decate-nates products of site-specific recombination in Escherichia coli. Genes Dev 1997; 11: 2580-2592. (Pubitemid 27438838)
-
(1997)
Genes and Development
, vol.11
, Issue.19
, pp. 2580-2592
-
-
Zechiedrich, E.L.1
Khodursky, A.B.2
Cozzarelli, N.R.3
|