The comparison of the effects of dexmedetomidine and midazolam sedation on electroencephalography in pediatric patients with febrile convulsion

Paediatric Anaesthesia

Volumn 21, Issue 4, 2011, Pages 373-378

  Aksu, Recep ^a   Kumandas, Sefer ^a   Akin, Aynur ^a   Bicer, Cihangir ^a   Gümüş, Hakan ^a   Güler, Gülen ^a   Per, Hüseyin ^a   Bayram, Adnan ^a   Boyaci, Adem ^a  

^a ERCIYES UNIVERSITY   (Turkey)

Author keywords

dexmedetomidine; electroencephalography; febrile convulsion; midazolam

Indexed keywords

DEXMEDETOMIDINE; MIDAZOLAM; MIDAZOLAM MALEATE;

ARTICLE; CHILD; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; ELECTROENCEPHALOGRAM; ELECTROENCEPHALOGRAPHY; FEBRILE CONVULSION; FEMALE; FOLLOW UP; FRONTAL CORTEX; HEART RATE; HUMAN; HYPOXIA; MAJOR CLINICAL STUDY; MALE; PARIETAL CORTEX; PRIORITY JOURNAL; SCORING SYSTEM; SEDATION; SLEEP;

ANOXIA; BLOOD PRESSURE; CHILD; CHILD, PRESCHOOL; CONSCIOUS SEDATION; DEXMEDETOMIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ELECTROENCEPHALOGRAPHY; FEMALE; HEART RATE; HUMANS; HYPNOTICS AND SEDATIVES; INFANT; MALE; MIDAZOLAM; SEIZURES, FEBRILE; SLEEP; TREATMENT OUTCOME;

EID: 79952478942     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2010.03516.x     Document Type: Article

References (19)

1. Sadleir LG, Scheffer IE,. Febrile seizures. BMJ 2007; 334: 307-311. (Pubitemid 46293967)
2. Mason KP, Zgleszewski SE, Dearden JL, et al. Dexmedetomidine for pediatric sedation for computed tomography imaging studies. Anesth Analg 2006; 103: 57-62. (Pubitemid 44036031)
3. Berkenbosch JW, Wankum PC, Tobias JD,. Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children. Pediatr Crit Care Med 2005; 6: 435-439.
4. Napoli KL, Ingall CG, Martin GR,. Safety and efficacy of chloral hydrate sedation in children undergoing echocardiography. J Pediatr 1996; 129: 287-291. (Pubitemid 27483803)
5. Mason KP, Sanborn P, Zurakowski D, et al. Superiority of pentobarbital versus chloral hydrate for sedation in infants during imaging. Radiology 2004; 230: 537-542. (Pubitemid 38133819)
6. Sanborn PA, Michna E, Zurakowski D, et al. Adverse cardiovascular and respiratory events after sedation of pediatric patients for imaging examinations. Radiology 2005; 237: 288-294. (Pubitemid 41346176)
7. Wang B, Bai Q, Jiao X, et al. Effect of sedative and hypnotic doses of propofol on the EEG activity of patients with or without a history of seizure disorders. J Neurosurg Anesthesiol 1997; 9: 335-340. (Pubitemid 27465485)
8. Mehta UC, Patel I, Castello FV,. EEG sedation for children with autism. J Dev Behav Pediatr 2004; 25: 102-104. (Pubitemid 38594418)
9. Virtanen R, Savola JM, Saano V, et al. Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist. Eur J Pharmacol 1988; 150: 9-14.
10. Lubisch N, Roskos R, Berkenbosch JW,. Dexmedetomidine for procedural sedation in children with autism and other behavior disorders. Pediatr Neurol 2009; 41: 88-94.
11. Ramsay MA, Savege TM, Simpson BR, et al. Controlled sedation with alphaxalone-alphadolone. Br Med J 1974; 2: 656-659.
12. Steward DJ,. A simplified scoring system for the post-operative recovery room. Can Anaesth Soc J 1975; 22: 111-113.
13. Ray T, Tobias JD,. Dexmedetomidine for sedation during electroencephalographic analysis in children with autism, pervasive developmental disorders, and seizure disorders. J Clin Anesth 2008; 20: 364-368.
14. Nelson LE, Lu J, Guo T, et al. The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology 2003; 98: 428-436. (Pubitemid 36592812)
15. Huupponen E, Maksimow A, Lapinlampi P, et al. Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep. Acta Anaesthesiol Scand 2008; 52: 289-294.
16. Mason KP, OMahony E, Zurakowski D, et al. Effects of dexmedetomidine sedation on the EEG in children. Pediatr Anesth 2009; 19: 1175-1183.
17. Greenblatt DJ, Ehrenberg BL, Culm KE, et al. Kinetics and EEG effects of midazolam during and after 1-minute, 1-hour, and 3-hour intravenous infusions. J Clin Pharmacol 2004; 44: 605-611. (Pubitemid 38668023)
18. Voepel-Lewis T, Malviya S, Prochaska G, et al. Sedation failures in children undergoing MRI and CT: is temperament a factor? Paediatr Anaesth 2000; 10: 319-323. (Pubitemid 30331174)
19. Singh R, Kumar N, Vajifdar H,. Midazolam as a sole sedative for computed tomography imaging in pediatric patients. Pediatr Anesth 2009; 19: 899-904.