Impact of 123I-FP-CIT (DaTSCAN) SPECT on the diagnosis and management of patients with dementia with Lewy bodies: A retrospective study

Nuclear Medicine Communications

Volumn 32, Issue 4, 2011, Pages 298-302

  Kemp, Paul M ^a   Clyde, Katie ^b   Holmes, Clive ^c  

^a UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^b Western Community Hospital   (United Kingdom)

^c MOORGREEN HOSPITAL   (United Kingdom)

Author keywords

DaTSCAN; dementia with Lewy bodies; imaging; single photon emission computed tomography

Indexed keywords

IOFLUPANE I 123; 2 CARBOMETHOXY 8 (3 FLUOROPROPYL) 3 (4 IODOPHENYL)TROPANE; 2-CARBOMETHOXY-8-(3-FLUOROPROPYL)-3-(4-IODOPHENYL)TROPANE; DIAGNOSTIC AGENT; TROPANE DERIVATIVE;

AGED; ARTICLE; BRAIN SCINTISCANNING; CLINICAL PRACTICE; DIFFUSE LEWY BODY DISEASE; FEMALE; HUMAN; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; RETROSPECTIVE STUDY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ALZHEIMER DISEASE; CORPUS STRIATUM; DIFFERENTIAL DIAGNOSIS; METHODOLOGY; OBSERVER VARIATION; PREDICTIVE VALUE; RADIOGRAPHY; SCINTISCANNING; SYNAPTOSOME;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CORPUS STRIATUM; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LEWY BODY DISEASE; MALE; OBSERVER VARIATION; PREDICTIVE VALUE OF TESTS; PRESYNAPTIC TERMINALS; RETROSPECTIVE STUDIES; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TROPANES;

EID: 79952454329     PISSN: 01433636     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNM.0b013e328343d4ec     Document Type: Article

References (15)

1. Alzheimer Europe. Dementia with Lewy bodies. Available at: http://www.alzheimer-europe.org/Dementia/Other-forms-of-dementia/ Neuro-Degenerative-Diseases/Dementia-with-Lewy-Bodies-DLB. [Accessed June 2010].
2. Re McKeith I, MintzerJ, Aarsland D, Burn D, Chiu H, Cohen-Mansfield J, et al. International Psychogeriatric Association Expert Meeting on DLB: dementia with Lewy bodies. Lancet Neurol 2004; 3:19-28.
3. 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study. Lancet Neurol 2007; 6:305-313. (Pubitemid 46367938)
4. 123I-FP-CIT SPECT in possible dementia with Lewy bodies. Br J Psych 2009; 194:34-39.
5. Walker Z, Costa DC, Walker RWH, Shaw K, Gacinovic S, Stevens T, et al. Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand. J Neurol Neurosurg Psychiatry 2002; 73:134-140.
6. Re McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien J, Feldman H, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 2005; 65:1863-1872. (Pubitemid 43970103)
7. National Institute for Health and Clinical Excellence. Dementia: supporting people with dementia and their carers in health and social care (Clinical Guideline 42). London: NICE; 2006.
8. O'Brien J, Colloby S, Fenwick J, Williams E, Firbank M, Burn D, et al. Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies. Arch Neurol 2004; 61:91 9-925. (Pubitemid 38747333)
9. Walker Z, Jaros E, Walker RWH, Lee L, Costa D, Livingstone G, et al. Dementia with Lewy bodies: a comparison of clinical diagnosis, FP-CIT SPECT imaging and autopsy. J Neurol Neurosurg Psychiatry 2007;78:1176-1181. (Pubitemid 350057277)
10. Walker RW, Walker Z. Dopamine transporter single photon emission computerized tomography in the diagnosis of dementia with Lewy bodies. MovDisord2009; 24 (Suppl 2):S754-S759.
11. McKeith IG, Galasko D, Kosaka K, Perry E, Dickson D, Hansen L, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 1996; 47:1113-1124. (Pubitemid 26374873)
12. McKeith IG, Fairbairn AF, Perry RH, Thompson P, Perry E. Neuropatía sensitivity of patients with senile dementia of the Lewy body type. BMJ 1992; 305:673-678.
13. Zaccai J, Brayne C, McKeith I, Matthews F, Ince PG. MRC Cognitive Function, Ageing Neuropathology Study. Patterns and stages of alpha-synucleinopathy: relevance in a population-based cohort. Neurol 2008; 70:1042-1048.
14. 123I-FP-CIT SPECT imaging of dopamine transporters in patients with cerebrovascular disease and clinical diagnosis of vascular parkinsonism. J Nuclear Med 2004; 45:1688-1693. (Pubitemid 47618476)
15. McKeith IG, O'Brien J. Dementia with Lewy bodies. Aust NZ J Psychiat 1999; 33:800-808. (Pubitemid 30015844)