An HIV-1 resistance polymorphism in TRIM5α gene among Chinese intravenous drug users

Journal of Acquired Immune Deficiency Syndromes

Volumn 56, Issue 4, 2011, Pages 306-311

  Liu, Feng Liang ^a,b,c   Qiu, Yu Qing ^d   Li, Hong ^e   Kuang, Yi Qun ^a,b,c   Tang, Xia ^a,b,c   Cao, Guang ^a,b,c   Tang, Nelson Leung Sang ^a,d,f   Zheng, Yong Tang ^a,b  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d Prince of Wales Hospital   (Hong Kong)

^e YUNNAN PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^f CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chinese; HIV 1; IDU; polymorphism; susceptibility; TRIM5a

Indexed keywords

TRIPARTITE MOTIF PROTEIN 5;

ADULT; ARTICLE; CHINESE; CONTROLLED STUDY; EXON; FEMALE; GENE; GENE FREQUENCY; GENE SEQUENCE; HOMOZYGOTE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INFECTION SENSITIVITY; INTRAVENOUS DRUG ABUSE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRIM5ALPHA GENE; VIRUS RESISTANCE;

ADOLESCENT; ADULT; AGED; AMINO ACID SUBSTITUTION; ASIAN CONTINENTAL ANCESTRY GROUP; CARRIER PROTEINS; GENE FREQUENCY; GENOTYPE; HIV INFECTIONS; HUMANS; IMMUNITY, INNATE; MIDDLE AGED; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; SUBSTANCE ABUSE, INTRAVENOUS; YOUNG ADULT;

EID: 79952444840     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318205a59b     Document Type: Article

References (30)

1. Johnson WE, Coffin JM. Constructing primate phylogenies from ancient retrovirus sequences. Proc Natl Acad Sci USA. 1999;96: 10254-10260. (Pubitemid 29422545)
2. Stremlau M, Owens CM, Perron MJ, et al. The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys. Nature. 2004;427:848-853. (Pubitemid 38297747)
3. Keckesova Z, Ylinen LM, Towers GJ. The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities. Proc Natl Acad Sci USA. 2004;101:10780-10785. (Pubitemid 38955819)
4. Hatziioannou T, Perez-Caballero D, Yang A, et al. Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha. Proc Natl Acad Sci USA. 2004;101:10774-10779. (Pubitemid 38955818)
5. Yap MW, Nisole S, Lynch C, et al. Trim5alpha protein restricts both HIV-1 and murine leukemia virus. Proc Natl Acad Sci USA. 2004;101: 10786-10791. (Pubitemid 38955820)
6. Nakayama EE, Miyoshi H, Nagai Y, et al. A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection. J Virol. 2005;79:8870-8877. (Pubitemid 40934797)
7. Langelier CR, Sandrin V, Eckert DM, et al. Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunode- ficiency virus type 1 replication. J Virol. 2008;82:11682-11694.
8. Takeuchi H, Matano T. Host factors involved in resistance to retroviral infection. Microbiol Immunol. 2008;52:318-325.
9. Javanbakht H, Diaz-Griffero F, Stremlau M, et al. The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha. J Biol Chem. 2005;280:26933-26940. (Pubitemid 41040729)
10. Anderson JL, Campbell EM, Wu X, et al. Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins. J Virol. 2006;80: 9754-9760. (Pubitemid 44435649)
11. Perez-Caballero D, Hatziioannou T, Yang A, et al. Human tripartite motif 5alpha domains responsible for retrovirus restriction activity and specificity. J Virol. 2005;79:8969-8978. (Pubitemid 40934808)
12. Yap MW, Nisole S, Stoye JP. A single amino acid change in the SPRY domain of human Trim5alpha leads to HIV-1 restriction. Curr Biol. 2005; 15:73-78. (Pubitemid 40084706)
13. Stremlau M, Perron M, Lee M, et al. Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor. Proc Natl Acad Sci USA. 2006;103:5514-5519.
14. Sawyer SL, Wu LI, Emerman M, et al. Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc Natl Acad Sci USA. 2005;102:2832-2837. (Pubitemid 40299877)
15. Song B, Gold B, O'Huigin C, et al. The B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primates. J Virol. 2005;79:6111-6121. (Pubitemid 40617216)
16. Liu HL, Wang YQ, Liao CH, et al. Adaptive evolution of primate TRIM5alpha, a gene restricting HIV-1 infection. Gene. 2005;362: 109-116.
17. Sawyer SL, Wu LI, Akey JM, et al. High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Curr Biol. 2006;16:95-100. (Pubitemid 43049892)
18. Goldschmidt V, Bleiber G, May M, et al. Role of common human TRIM5alpha variants in HIV-1 disease progression. Retrovirology. 2006; 3:54.
19. Speelmon EC, Livingston-Rosanoff D, Li SS, et al. Genetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infection. J Virol. 2006;80:2463-2471. (Pubitemid 43271552)
20. Javanbakht H, An P, Gold B, et al. Effects of human TRIM5alpha polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection. Virology. 2006;354:15-27. (Pubitemid 44468115)
21. Nakayama EE, CarpentierW, Costagliola D, et al.Wild type and H43Y variant of human TRIM5alpha show similar anti-human immunodeficiency virus type 1 activity both in vivo and in vitro. Immunogenetics. 2007;59:511-515. (Pubitemid 46684724)
22. Nakajima T, Nakayama EE, Kaur G, et al. Impact of novel TRIM5alpha variants, Gly110Arg and G176del, on the anti-HIV-1 activity and the susceptibility to HIV-1 infection. AIDS. 2009;23:2091-2100.
23. vanManenD, Rits MA, Beugeling C, et al. The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection. PLoS Pathog. 2008;4:e18.
24. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994;22:4673-4680. (Pubitemid 24354800)
25. Mehta CR, Patel NR, Gray R. Computing an exact confidence-interval for the common odds ratio in several 2x2 contingency-tables. J Am Stat Assoc. 1985;80:969-973.
26. Morrow WJ, Homsy J, Eichberg JW, et al. Long-term observation of baboons, rhesus monkeys, and chimpanzees inoculated with HIV and given periodic immunosuppressive treatment. AIDS Res Hum Retroviruses. 1989;5:233-245. (Pubitemid 19116052)
27. Sawyer SL, Emerman M, Malik HS. Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals. PloS Pathog. 2007; 3:e197.
28. Sewram S, Singh R, Kormuth E, et al. Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection. J Infect Dis. 2009; 199:1657-1663.
29. Richardson MW, Carroll RG, Stremlau M, et al. Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha. J Virol. 2008;82:11117-11128.
30. Nakayama EE, Shioda T. Anti-retroviral activity of TRIM5 alpha. Rev Med Virol. 2010;20:77-92.