Hydroxyethyl starches: What do we still know?

Anesthesia and Analgesia

Volumn 112, Issue 3, 2011, Pages 507-511

  Reinhart, Konrad ^a   Takala, Jukka ^b  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; HETASTARCH;

ANALGESIA; ANESTHESIA; CLINICAL EFFECTIVENESS; CLINICAL RESEARCH; COLLOID; CRYSTALLOID; FLUID THERAPY; FRAUD; HUMAN; MEDICAL LITERATURE; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; RESUSCITATION; RETRACTED ARTICLE; REVIEW; SAFETY; SCIENTIFIC MISCONDUCT;

EID: 79952444467     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3182099c49     Document Type: Editorial

References (21)

1. Moore B. The balance of colloid and crystalloid in cholera, shock and allied conditions. Br Med J 1919;2:490-2
2. Shafer SL. Notice of retraction. Anesth Analg 2010;111:1567
3. Shafer SL. Notice of retraction. Anesth Analg 2009;108:1350
4. Shafer SL. Tattered threads. Anesth Analg 2009;108:1361-3
5. Perel P, Roberts I. Colloids versus crystalloids for fluid resus-citation in critically ill patients. Cochrane Database Syst Rev 2009;4:CD000567
6. Bunn F, Trivedi D, Ashraf S. Colloid solutions for fluid resuscitation. Cochrane Database Syst Rev 2008;1:CD001319
7. Dart AB, Mutter TC, Ruth CA, Taback SP. Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function. Cochrane Database Syst Rev 2010;1:CD007594
8. Zarychanski R, Turgeon AF, Fergusson DA, Cook DJ, Hebert P, Bagshaw SM, Monsour D, McIntyre LA. Renal outcomes and mortality following hydroxyethyl starch resuscitation of criti-cally ill patients: systematic review and meta-analysis of ran-domized trials. Open Med 2009;3:E196-209
9. American Thoracic Society. Evidence-based colloid use in the critically ill: American Thoracic Society Consensus Statement. Am J Respir Crit Care Med 2004;170:1247-59
10. Powell-Tuck J, Gosling P, Lobo DN, Allison SP, Carlson GL, Gore M, Lewington AJ, Pearse RM, Mythen MG. British Consensus Guidelines on Intravenous Fluid Therapy for Adult Surgical Patients (GIFTASUP). 2008. London: NHS National Library of Health. Available at: http://www.bapen.org.uk/pdfs/bapen- pubs/giftasup.pdf. Accessed January 4, 2011
11. Choi PT, Yip G, Quinonez LG, Cook DJ. Crystalloids vs. colloids in fluid resuscitation: a systematic review. Crit Care Med 1999;27:200-10 (Pubitemid 29052838)
12. Schierhout G, Roberts I. Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomised trials. BMJ 1998;316:961-4 (Pubitemid 28135143)
13. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004;350:2247-56 (Pubitemid 38669207)
14. Finfer S, Liu B, Taylor C, Bellomo R, Billot L, Cook D, Du B, McArthur C, Myburgh J; SAFE TRIPS Investigators. Resuscitation fluid use in critically ill adults: an international cross sectional study in 391 intensive care units. Crit Care 2010;14:R185
15. Neff TA, Pestel G, Kurz A, Stocker R. Fluid management in Switzerland: current practice and trends: A-798. Eur J Anaes-thesiol 2006;23:206
16. Brunkhorst FM, Englel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K; German Competence Network Sepsis (SepNet). Intensive insulin therapy and pentastarch resuscita-tion in severe sepsis. N Engl J Med 2008;358:125-39
17. Boldt J. Modern rapidly degradable hydroxyethyl starches: current concepts. Anesth Analg 2009;108:1574-82
18. Postmarketing Drug Safety Evaluations. Available at: http://www. fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/ucm204091. htm. Accessed January 4, 2011
19. Hartog C, Reinhart K. CONTRA: hydroxyethyl starch solu-tions are unsafe in critically ill patients. Intensive Care Med 2009;35:1337-42
20. Hartog CS, Kohl M, Reinhart K. Randomized controlled trials are not designed to prove the safety of third-generation hydroxyethyl starch for resuscitation: results from a systematic review. Crit Care 2010;14:P2
21. Hartog CS, Kohl M, Reinhart K. A systematic review of 3rd generation hydroxyethyl starch (HES 130/0.4) in resuscitation: safety not adequately addressed. Anesth Analg (in press)