Study of ageing of dry powder inhaler and metered dose inhaler by atomic force microscopy

Powder Technology

Volumn 208, Issue 2, 2011, Pages 252-259

  Harder, Christophe ^a,b   Lesniewska, Eric ^a,b   Laroche, Christophe ^c  

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c GLAXOSMITHKLINE   (France)

Author keywords

Atomic force microscopy; Dry powder inhaler; Interaction force; Metered dose inhaler; Surface reactivity

Indexed keywords

ACTIVE SUBSTANCE; ADHESIVE FORCE; BINARY MIXING; COLLOID PROBE AFM; CONTROLLED ATMOSPHERE; DIRECT ANALYSIS; DRY POWDER INHALER; INTERACTION FORCE; LIQUID MEDIUM; LIQUID PHASE; METERED-DOSE INHALERS; MORPHOLOGY EVOLUTION; PARTICLE-PARTICLE INTERACTIONS; POWDER QUALITY; RELATIVE HUMIDITIES; SEM; STANDARD ANALYSIS; SURFACE REACTIVITY;

ATMOSPHERIC HUMIDITY; ATOMIZERS; ELECTRIC IMPEDANCE; LIQUIDS; PARTICLE INTERACTIONS; SCANNING ELECTRON MICROSCOPY;

ATOMIC FORCE MICROSCOPY;

ARTICLE; ATOMIC FORCE MICROSCOPY; CHEMICAL STRUCTURE; CONTROLLED ATMOSPHERE; CONTROLLED STUDY; DRUG STORAGE; DRY POWDER; HUMIDITY; METERED DOSE INHALER; MOLECULAR INTERACTION; MORPHOLOGY; NANOANALYSIS; PARTICLE SIZE; POWDER INHALER; SCANNING ELECTRON MICROSCOPY; TEMPERATURE SENSITIVITY;

EID: 79952430884     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.08.013     Document Type: Article

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