A third troponin T blood sample is not cost-effective in patients with suspected non-ST segment elevation acute coronary syndrome

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 71, Issue 2, 2011, Pages 117-122

  Alzuhairi, Karam S M ^a   Hjortshøj, Søren ^a   Kristensen, Søren Risom ^a   Ravkilde, Jan ^a  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Acute coronary syndrome; health care economics and organisations; hospital costs; myocardial infarction; troponin

Indexed keywords

TROPONIN T;

ACUTE CORONARY SYNDROME; ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; BLOOD SAMPLING; COST EFFECTIVENESS ANALYSIS; ELECTROCARDIOGRAPHY; FEMALE; HEALTH CARE COST; HOSPITAL ADMISSION; HOSPITALIZATION COST; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THIRD BLOOD SAMPLING;

ACUTE CORONARY SYNDROME; ADULT; AGED; AGED, 80 AND OVER; BLOOD SPECIMEN COLLECTION; COST-BENEFIT ANALYSIS; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; LENGTH OF STAY; MALE; MIDDLE AGED; PATIENT SELECTION; TROPONIN T;

EID: 79952425619     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.3109/00365513.2010.542486     Document Type: Article

References (16)

1. Hamm CW, Ravkilde J, Gerhardt W, Jorgensen P, Peheim E, Ljungdahl L, Goldmann B, Katus HA. The prognostic value of serum troponin T in unstable angina. N Engl J Med 1992;327:146-50.
2. Lindahl B, Venge P, Wallentin L. Relation between troponin T and the risk of subsequent cardiac events in unstable cor-onary artery disease. The FRISC study group. Circulation 1996;93:1651-7. (Pubitemid 26131341)
3. Lindahl B, Venge P, Wallentin L. Troponin T identifies patients with unstable coronary artery disease who benefit from long-term antithrombotic protection. Fragmin in Unstable Coronary Artery Disease (FRISC) Study Group. J Am Coll Cardiol 1997;29:43-8. (Pubitemid 27028718)
4. Luscher MS, Thygesen K, Ravkilde J, Heickendorff L. Applicability of cardiac troponin T and I for early risk stratification in unstable coronary artery disease. TRIM Study Group. Thrombin Inhibition in Myocardial ischemia. Circulation 1997;96:2578-85. (Pubitemid 27451349)
5. Antman EM, Tanasijevic MJ, Thompson B, Schactman M, McCabe CH, Cannon CP, Fischer GA, Fung AY, Thompson C, Wybenga D, Braunwald E. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996;335:1342-9. (Pubitemid 26360452)
6. Apple FS, Smith SW, Pearce LA, Ler R, Murakami MM. Use of the Centaur TnI-Ultra assay for detection of myocar-dial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. Clin Chem 2008;54:723-8. (Pubitemid 351573705)
7. Morrow DA, Rifai N, Sabatine MS, Ayanian S, Murphy SA, de Lemos JA, Braunwald E, Cannon CP. Evaluation of the AccuTnI cardiac troponin I assay for risk assessment in acute coronary syndromes. Clin Chem 2003;49:1396-8. (Pubitemid 36900627)
8. Thygesen K, Ravkilde J. Triage of chest pain patients based on early risk stratification using sensitive cardiac markers. Eur Heart J 2000;21:347-8. (Pubitemid 30107549)
9. Newby LK, Christenson RH, Ohman EM, Armstrong PW, Thompson TD, Lee KL, Hamm CW, Katus HA, Cianciolo C, Granger CB, Topol EJ, Califf RM. Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. The GUSTO-IIa Investiga-tors. Circulation 1998;98:1853-9. (Pubitemid 28509280)
10. Thygesen K, Alpert JS, White HD, Joint ESC/ACCF/AHA/WHF Task Force for the Redefinition of Myocardial Infarc-tion. Universal definition of myocardial infarction. Eur Heart J 2007;28:2525-38.
11. Hjortshoj S, Dethlefsen C, Kristensen SR, Ravkilde J. Improved assay of cardiac troponin I is more sensitive than other assays of necrosis markers. Scand J Clin Lab Invest 2008;68:130-3. (Pubitemid 351481739)
12. Szymanski FM, Grabowski M, Filipiak KJ, Karpinski G, Hrynkiewicz A, Stolarz P, Oreziak A, Rudowski R, Opolski G. Prognostic implications of myocardial necrosis triad markers ' concentration measured at admission in patients with suspected acute coronary syndrome. Am J Emerg Med 2007;25:65-8. (Pubitemid 44869007)
13. Task Force for Diagnosis and Treatment of Non-ST-Seg-ment Elevation Acute Coronary Syndromes of European Society of Cardiology, Bassand JP, Hamm CW, Ardissino D, Boersma E, Budaj A, Fernandez-Aviles F, Fox KA, Hasdai D, Ohman EM, Wallentin L, Wijns W Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Eur Heart J 2007;28:1598-1660.
14. Panteghini M, Pagani F, Yeo KT, Apple FS, Christenson RH, Dati F, Mair J, Ravkilde J, Wu AH, Committee on Standard-ization of Markers of Cardiac Damage of the IFCC. Evaluation of imprecision for cardiac troponin assays at low-range concentrations. Clin Chem 2004;50:327-32. (Pubitemid 38156373)
15. Katus HA, Rempppis A, Scheffold T, Diederich CH, Kuebler W. Intracellular compartmentation of cardiac tro-ponin T and its release kinetics in patients with reperfused and non-reperfused myocardial infarction. Am J Cardiol 1991;67:1360-7.
16. Kurz K, Giannitsis E, Becker M, Hess G, Zdunek D, Katus HA. Comparison of the new high sensitive cardiac troponin T with myoglobin, h-FABP and cTnT for early identification of myocardial necrosis in the acute coronary syndrome. Clin Res Cardiol 2010; 18 September [e-pub ahead of print].