메뉴 건너뛰기




Volumn 60, Issue 3, 2011, Pages 1000-1007

The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: Evidence for interaction with obesity in diabetic patients

(26)  Bacci, Simonetta a   Rizza, Stefano b   Prudente, Sabrina a   Spoto, Belinda c   Powers, Christine d   Facciorusso, Antonio a   Pacilli, Antonio a   Lauro, Davide b   Testa, Alessandra c   Zhang, Yuan Yuan d,e   Di Stolfo, Giuseppe a   Mallamaci, Francesca c   Tripepi, Giovanni c   Xu, Rui d,e   Mangiacotti, Davide a   Aucella, Filippo a   Lauro, Renato b   Gervino, Ernest V e,f   Hauser, Thomas H e,f   Copetti, Massimiliano a   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; DEATH; DIABETES MELLITUS; DIABETIC PATIENT; DIALYSIS; FEMALE; GENETIC POLYMORPHISM; HEART INFARCTION; HIGH RISK PATIENT; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; STROKE;

EID: 79952392468     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-1300     Document Type: Article
Times cited : (36)

References (51)
  • 1
    • 77649126524 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2010 Update: A report from the American Heart Association
    • Writing Group Members; American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D, Adams RJ, Brown TM, et al.; Writing Group Members; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics - 2010 update: a report from the American Heart Association. Circulation 2010;121:e46-e215
    • (2010) Circulation , vol.121
    • Lloyd-Jones, D.1    Adams, R.J.2    Brown, T.M.3
  • 2
    • 30044443649 scopus 로고    scopus 로고
    • Diabetes and obesity: The twin epidemics
    • DOI 10.1038/nm0106-75
    • Smyth S, Heron A. Diabetes and obesity: the twin epidemics. Nat Med 2006;12:75-80 (Pubitemid 43050080)
    • (2006) Nature Medicine , vol.12 , Issue.1 , pp. 75-80
    • Smyth, S.1    Heron, A.2
  • 3
    • 8344237456 scopus 로고    scopus 로고
    • Overweight and obesity and the burden of disease and disability in elderly men
    • DOI 10.1038/sj.ijo.0802775
    • Goya Wannamethee S, Gerald Shaper A, Whincup PH, Walker M. Overweight and obesity and the burden of disease and disability in elderly men. Int J Obes Relat Metab Disord 2004;28:1374-1382 (Pubitemid 39481840)
    • (2004) International Journal of Obesity , vol.28 , Issue.11 , pp. 1374-1382
    • Wannamethee, S.G.1    Shaper, A.G.2    Whincup, P.H.3    Walker, M.4
  • 4
    • 53849092685 scopus 로고    scopus 로고
    • Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic
    • Silver Spring
    • Wang Y, Beydoun MA, Liang L, Caballero B, Kumanyika SK. Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic. Obesity (Silver Spring) 2008;16:2323-2330
    • (2008) Obesity , vol.16 , pp. 2323-2330
    • Wang, Y.1    Beydoun, M.A.2    Liang, L.3    Caballero, B.4    Kumanyika, S.K.5
  • 5
    • 42149106981 scopus 로고    scopus 로고
    • Identifying the susceptibility genes for coronary artery disease: From hyperbole through doubt to cautious optimism
    • DOI 10.1111/j.1365-2796.2008.01958.x
    • Hamsten A, Eriksson P. Identifying the susceptibility genes for coronary artery disease: from hyperbole through doubt to cautious optimism. J Intern Med 2008;263:538-552 (Pubitemid 351533558)
    • (2008) Journal of Internal Medicine , vol.263 , Issue.5 , pp. 538-552
    • Hamsten, A.1    Eriksson, P.2
  • 9
    • 61349177857 scopus 로고    scopus 로고
    • New susceptibility locus for coronary artery disease on chromosome 3q22.3
    • Italian Atherosclerosis, Thrombosis, and Vascular Biology Working Group; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium; Cardiogenics Consortium
    • Erdmann J, Grosshennig A, Braund PS, et al.; Italian Atherosclerosis, Thrombosis, and Vascular Biology Working Group; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium; Cardiogenics Consortium. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet 2009;41:280-282
    • (2009) Nat Genet , vol.41 , pp. 280-282
    • Erdmann, J.1    Grosshennig, A.2    Braund, P.S.3
  • 10
    • 70749096913 scopus 로고    scopus 로고
    • Genome-wide association of early-onset myocardial infarction with common single polymorphisms, common copy number variants, and rare copy number variants
    • Myocardial Infarction Genetics Consortium
    • Myocardial Infarction Genetics Consortium, Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with common single polymorphisms, common copy number variants, and rare copy number variants. Nat Genet 2009;41:334-341
    • (2009) Nat Genet , vol.41 , pp. 334-341
    • Kathiresan, S.1    Voight, B.F.2    Purcell, S.3
  • 11
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-1607
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 12
    • 0343209773 scopus 로고    scopus 로고
    • Insulin sensitivity and atherosclerosis
    • The Insulin Resistance Atherosclerosis Study (IRAS) Investigators
    • Howard G, O'Leary DH, Zaccaro D, et al.; The Insulin Resistance Atherosclerosis Study (IRAS) Investigators. Insulin sensitivity and atherosclerosis. Circulation 1996;93:1809-1817
    • (1996) Circulation , vol.93 , pp. 1809-1817
    • Howard, G.1    O'Leary, D.H.2    Zaccaro, D.3
  • 13
    • 0035985223 scopus 로고    scopus 로고
    • Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death
    • DOI 10.1046/j.1464-5491.2002.00719.x
    • Hedblad B, Nilsson P, Engström G, Berglund G, Janzon L. Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death. Diabet Med 2002;19:470-475 (Pubitemid 34639157)
    • (2002) Diabetic Medicine , vol.19 , Issue.6 , pp. 470-475
    • Hedblad, B.1    Nilsson, P.2    Engstrom, G.3    Berglund, G.4    Janzon, L.5
  • 14
    • 30744460648 scopus 로고    scopus 로고
    • Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study
    • DOI 10.2337/diabetes.54.11.3252
    • Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB Sr, Wilson PW. Insulin resistance, the metabolic syndrome, and incident cardiovascular events in the Framingham Offspring Study. Diabetes 2005;54:3252-3257 (Pubitemid 43334382)
    • (2005) Diabetes , vol.54 , Issue.11 , pp. 3252-3257
    • Rutter, M.K.1    Meigs, J.B.2    Sullivan, L.M.3    D'Agostino Sr., R.B.4    Wilson, P.W.5
  • 15
    • 0742266631 scopus 로고    scopus 로고
    • The metabolic syndrome and chronic kidney disease in U.S. adults
    • Chen J, Muntner P, Hamm LL, et al. The metabolic syndrome and chronic kidney disease in U.S. adults. Ann Intern Med 2004;140:167-174
    • (2004) Ann Intern Med , vol.140 , pp. 167-174
    • Chen, J.1    Muntner, P.2    Hamm, L.L.3
  • 16
    • 33646380621 scopus 로고    scopus 로고
    • Insulin resistance and the cluster of abnormalities related to the metabolic syndrome are associated with reduced glomerular filtration rate in patients with type 2 diabetes
    • De Cosmo S, Trevisan R, Minenna A, et al. Insulin resistance and the cluster of abnormalities related to the metabolic syndrome are associated with reduced glomerular filtration rate in patients with type 2 diabetes. Diabetes Care 2006;29:432-434 (Pubitemid 44106535)
    • (2006) Diabetes Care , vol.29 , Issue.2 , pp. 432-434
    • De Cosmo, S.1    Trevisan, R.2    Minenna, A.3    Vedovato, M.4    Viti, R.5    Santini, S.A.6    Dodesini, A.R.7    Fioretto, P.8    Trischitta, V.9
  • 19
    • 3042824999 scopus 로고    scopus 로고
    • Identification of quantitative trait loci for glucose homeostasis: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
    • Insulin Resistance Atherosclerosis Study Family Study
    • Rich SS, Bowden DW, Haffner SM, et al.; Insulin Resistance Atherosclerosis Study Family Study. Identification of quantitative trait loci for glucose homeostasis: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes 2004;53:1866-1875
    • (2004) Diabetes , vol.53 , pp. 1866-1875
    • Rich, S.S.1    Bowden, D.W.2    Haffner, S.M.3
  • 20
    • 12144273136 scopus 로고    scopus 로고
    • Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins
    • DOI 10.2337/diabetes.54.1.275
    • Poulsen P, Levin K, Petersen I, Christensen K, Beck-Nielsen H, Vaag A. Heritability of insulin secretion, peripheral and hepatic insulin action, and intracellular glucose partitioning in young and old Danish twins. Diabetes 2005;54:275-283 (Pubitemid 40105123)
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 275-283
    • Poulsen, P.1    Levin, K.2    Petersen, I.3    Christensen, K.4    Beck-Nielsen, H.5    Vaag, A.6
  • 21
    • 39149099952 scopus 로고    scopus 로고
    • The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities
    • DOI 10.1210/er.2007-0004
    • Goldfine ID, Maddux BA, Youngren JF, et al. The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities. Endocr Rev 2008;29:62-75 (Pubitemid 351252747)
    • (2008) Endocrine Reviews , vol.29 , Issue.1 , pp. 62-75
    • Goldfine, I.D.1    Maddux, B.A.2    Youngren, J.F.3    Reaven, G.4    Accili, D.5    Trischitta, V.6    Vigneri, R.7    Frittitta, L.8
  • 23
    • 0035080028 scopus 로고    scopus 로고
    • The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121)
    • Costanzo BV, Trischitta V, Di Paola R, et al. The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121). Diabetes 2001;50:831-836
    • (2001) Diabetes , vol.50 , pp. 831-836
    • Costanzo, B.V.1    Trischitta, V.2    Di Paola, R.3
  • 24
    • 70349574150 scopus 로고    scopus 로고
    • ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells
    • Bacci S, Di Paola R, Menzaghi C, et al. ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells. Arterioscler Thromb Vasc Biol 2009;29:1678-1683
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1678-1683
    • Bacci, S.1    Di Paola, R.2    Menzaghi, C.3
  • 26
    • 48249098981 scopus 로고    scopus 로고
    • Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study
    • Stolerman ES, Manning AK, McAteer JB, et al. Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study. Diabetes 2008;57:1971-1977
    • (2008) Diabetes , vol.57 , pp. 1971-1977
    • Stolerman, E.S.1    Manning, A.K.2    McAteer, J.B.3
  • 27
    • 58149354288 scopus 로고    scopus 로고
    • Role of the ENPP1 K121Q polymorphism in glucose homeostasis
    • Baratta R, Rossetti P, Prudente S, et al. Role of the ENPP1 K121Q polymorphism in glucose homeostasis. Diabetes 2008;57:3360-3364
    • (2008) Diabetes , vol.57 , pp. 3360-3364
    • Baratta, R.1    Rossetti, P.2    Prudente, S.3
  • 28
    • 33746726490 scopus 로고    scopus 로고
    • Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects
    • DOI 10.1007/s00125-006-0353-x
    • Grarup N, Urhammer SA, Ek J, et al. Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects. Diabetologia 2006;49:2097-2104 (Pubitemid 44168477)
    • (2006) Diabetologia , vol.49 , Issue.9 , pp. 2097-2104
    • Grarup, N.1    Urhammer, S.A.2    Ek, J.3    Albrechtsen, A.4    Glumer, C.5    Borch-Johnsen, K.6    Jorgensen, T.7    Hansen, T.8    Pedersen, O.9
  • 31
    • 77951993470 scopus 로고    scopus 로고
    • ENPP1 K121Q polymorphism and ischemic heart disease in diabetic patients
    • Moehlecke M, Kramer CK, Leitão CB, et al. [ENPP1 K121Q polymorphism and ischemic heart disease in diabetic patients]. Arq Bras Cardiol 2010;94: 157-161, 168-173, 159-163
    • (2010) Arq Bras Cardiol , vol.94
    • Moehlecke, M.1    Kramer, C.K.2    Leitão, C.B.3
  • 32
    • 85056062179 scopus 로고    scopus 로고
    • ENPP1 K121Q polymorphism is not related to type 2 diabetes mellitus, features of metabolic syndrome, and diabetic cardiovascular complications in a Chinese population
    • Chen MP, Chung FM, Chang DM, et al. ENPP1 K121Q polymorphism is not related to type 2 diabetes mellitus, features of metabolic syndrome, and diabetic cardiovascular complications in a Chinese population. Rev Diabet Stud 2006;3:21-30
    • (2006) Rev Diabet Stud , vol.3 , pp. 21-30
    • Chen, M.P.1    Chung, F.M.2    Chang, D.M.3
  • 33
    • 58349107086 scopus 로고    scopus 로고
    • Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes
    • De Cosmo S, Minenna A, Zhang YY, et al. Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes. Am J Kidney Dis 2009;53:273-280
    • (2009) Am J Kidney Dis , vol.53 , pp. 273-280
    • De Cosmo, S.1    Minenna, A.2    Zhang, Y.Y.3
  • 34
    • 29244437161 scopus 로고    scopus 로고
    • The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease
    • Testa A, Spoto B, Tripepi G, et al. The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease. J Hypertens 2005;23:1825-1830 (Pubitemid 41830422)
    • (2005) Journal of Hypertension , vol.23 , Issue.10 , pp. 1825-1830
    • Testa, A.1    Spoto, B.2    Tripepi, G.3    Mallamaci, F.4    Malatino, L.5    Fatuzzo, P.6    Maas, R.7    Boeger, R.8    Zoccali, C.9
  • 35
    • 56749092202 scopus 로고    scopus 로고
    • Diabetics on dialysis in Italy: A nationwide epidemiological study
    • Panzetta G, Basile C, Santoro A, et al. Diabetics on dialysis in Italy: a nationwide epidemiological study. Nephrol Dial Transplant 2008;23:3988-3995
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 3988-3995
    • Panzetta, G.1    Basile, C.2    Santoro, A.3
  • 37
    • 57049150338 scopus 로고    scopus 로고
    • Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes
    • Doria A, Wojcik J, Xu R, et al. Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes. JAMA 2008;300:2389-2397
    • (2008) JAMA , vol.300 , pp. 2389-2397
    • Doria, A.1    Wojcik, J.2    Xu, R.3
  • 38
    • 0031920047 scopus 로고    scopus 로고
    • Comparison of meta-analysis versus analysis of variance of individual patient data
    • DOI 10.2307/2534018
    • Olkin I, Sampson A. Comparison of meta-analysis versus analysis of variance of individual patient data. Biometrics 1998;54:317-322 (Pubitemid 28158806)
    • (1998) Biometrics , vol.54 , Issue.1 , pp. 317-322
    • Olkin, I.1    Sampson, A.2
  • 39
    • 3242770671 scopus 로고    scopus 로고
    • Overall C as a measure of discrimination in survival analysis: Model specific population value and confidence interval estimation
    • DOI 10.1002/sim.1802
    • Pencina MJ, D'Agostino RB. Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation. Stat Med 2004;23:2109-2123 (Pubitemid 38968032)
    • (2004) Statistics in Medicine , vol.23 , Issue.13 , pp. 2109-2123
    • Penciana, M.J.1    D'Agostino, R.B.2
  • 40
    • 38849091997 scopus 로고    scopus 로고
    • Evaluating the added predictive ability of a new marker: From area under the ROC curve to reclassification and beyond
    • discussion 207-212
    • Pencina MJ, D'Agostino RB Sr, D'Agostino RB Jr, Vasan RS. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med 2008;27:157-172; discussion 207-212
    • (2008) Stat Med , vol.27 , pp. 157-172
    • Pencina, M.J.1    D'Agostino Sr., R.B.2    D'Agostino Jr., R.B.3    Vasan, R.S.4
  • 41
    • 33645389912 scopus 로고    scopus 로고
    • Impact of body mass index on cardiac mortality in patients with known or suspected coronary artery disease undergoing myocardial perfusion single-photon emission computed tomography
    • Kang X, Shaw LJ, Hayes SW, et al. Impact of body mass index on cardiac mortality in patients with known or suspected coronary artery disease undergoing myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol 2006;47:1418-1426
    • (2006) J Am Coll Cardiol , vol.47 , pp. 1418-1426
    • Kang, X.1    Shaw, L.J.2    Hayes, S.W.3
  • 42
    • 0037337398 scopus 로고    scopus 로고
    • Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients
    • DOI 10.1046/j.1523-1755.2003.00803.x
    • Kalantar-Zadeh K, Block G, Humphreys MH, Kopple JD. Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients. Kidney Int 2003;63:793-808 (Pubitemid 36315558)
    • (2003) Kidney International , vol.63 , Issue.3 , pp. 793-808
    • Kalantar-Zadeh, K.1    Block, G.2    Humphreys, M.H.3    Kopple, J.D.4
  • 43
    • 1942420812 scopus 로고    scopus 로고
    • Reverse epidemiology of conventional cardiovascular risk factors in patients with chronic heart failure
    • DOI 10.1016/j.jacc.2003.11.039, PII S073510970400172X
    • Kalantar-Zadeh K, Block G, Horwich T, Fonarow GC. Reverse epidemiology of conventional cardiovascular risk factors in patients with chronic heart failure. J Am Coll Cardiol 2004;43:1439-1444 (Pubitemid 38496352)
    • (2004) Journal of the American College of Cardiology , vol.43 , Issue.8 , pp. 1439-1444
    • Kalantar-Zadeh, K.1    Block, G.2    Horwich, T.3    Fonarow, G.C.4
  • 46
    • 42449116149 scopus 로고    scopus 로고
    • The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: Evidence from an updated meta-analysis in 42,042 subjects
    • ENPP1 Consortium
    • McAteer JB, Prudente S, Bacci S, et al.; ENPP1 Consortium. The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects. Diabetes 2008;57:1125-1130
    • (2008) Diabetes , vol.57 , pp. 1125-1130
    • McAteer, J.B.1    Prudente, S.2    Bacci, S.3
  • 47
    • 70749139756 scopus 로고    scopus 로고
    • Insulin signaling regulating genes: Effect on T2DM and cardiovascular risk
    • Prudente S, Morini E, Trischitta V. Insulin signaling regulating genes: effect on T2DM and cardiovascular risk. Nat Rev Endocrinol 2009;5:682-693
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 682-693
    • Prudente, S.1    Morini, E.2    Trischitta, V.3
  • 48
    • 33750595696 scopus 로고    scopus 로고
    • New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals
    • DOI 10.2337/db06-0191
    • Bochenski J, Placha G, Wanic K, et al. New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals. Diabetes 2006;55:2626-2630 (Pubitemid 44871165)
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2626-2630
    • Bochenski, J.1    Placha, G.2    Wanic, K.3    Malecki, M.4    Sieradzki, J.5    Warram, J.H.6    Krolewski, A.S.7
  • 49
    • 44649133311 scopus 로고    scopus 로고
    • The genetic susceptibility to type 2 diabetes may be modulated by obesity status: Implications for association studies
    • Cauchi S, Nead KT, Choquet H, et al. The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies. BMC Med Genet 2008;9:45
    • (2008) BMC Med Genet , vol.9 , pp. 45
    • Cauchi, S.1    Nead, K.T.2    Choquet, H.3
  • 50
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 2004;109(Suppl. 1):III27-III32
    • (2004) Circulation , vol.109 , Issue.SUPPL. 1
    • Davignon, J.1    Ganz, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.