메뉴 건너뛰기




Volumn 493, Issue , 2011, Pages 321-356

Fragment screening purely with protein crystallography

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID BINDING PROTEIN 4; LIQUID NITROGEN;

EID: 79952392408     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-381274-2.00013-3     Document Type: Chapter
Times cited : (20)

References (42)
  • 2
    • 76449098262 scopus 로고    scopus 로고
    • PHENIX: A comprehensive Python-based system for macromolecular structure solution
    • P.D. Adams PHENIX: A comprehensive Python-based system for macromolecular structure solution Acta Crystallogr. D 66 2010 213 221
    • (2010) Acta Crystallogr. D , vol.66 , pp. 213-221
    • Adams, P.D.1
  • 5
    • 74549178560 scopus 로고    scopus 로고
    • MolProbity: All-atom structure validation for macromolecular crystallography
    • V.B. Chen MolProbity: All-atom structure validation for macromolecular crystallography Acta Crystallogr. D 66 2010 12 21
    • (2010) Acta Crystallogr. D , vol.66 , pp. 12-21
    • Chen, V.B.1
  • 6
    • 0141726877 scopus 로고    scopus 로고
    • A 'Rule of Three' for fragment-based lead discovery?
    • DOI 10.1016/S1359-6446(03)02831-9, PII S1359644603028319
    • M. Congreve A [']Rule of Three' for fragment-based lead discovery? Drug Discov. Today 8 2003 876 877 (Pubitemid 37194496)
    • (2003) Drug Discovery Today , vol.8 , Issue.19 , pp. 876-877
    • Congreve, M.1    Carr, R.2    Murray, C.3    Jhoti, H.4
  • 7
    • 68549132502 scopus 로고    scopus 로고
    • Discovery of leukotriene A4 hydrolase Inhibitors using metabolomics biased fragment crystallography
    • D.R. Davies Discovery of leukotriene A4 hydrolase Inhibitors using metabolomics biased fragment crystallography J. Med. Chem. 52 2009 4694 4715
    • (2009) J. Med. Chem. , vol.52 , pp. 4694-4715
    • Davies, D.R.1
  • 10
    • 44449118921 scopus 로고    scopus 로고
    • Fatty acid-binding proteins: Role in metabolic diseases and potential as drug targets
    • DOI 10.1038/nrd2589, PII NRD2589
    • M. Furuhashi, and G.S. Hotamisligil Fatty acid-binding proteins: Role in metabolic diseases and potential as drug targets Nat. Rev. Drug Discov. 7 2008 489 503 (Pubitemid 351767117)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.6 , pp. 489-503
    • Furuhashi, M.1    Hotamisligil, G.S.2
  • 12
    • 33847381100 scopus 로고    scopus 로고
    • A decade of fragment-based drug design: Strategic advances and lessons learned
    • DOI 10.1038/nrd2220, PII NRD2220
    • P.J. Hajduk, and J. Greer A decade of fragment-based drug design: Strategic advances and lessons learned Nat. Rev. Drug Discov. 6 2007 211 219 (Pubitemid 46344625)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.3 , pp. 211-219
    • Hajduk, P.J.1    Greer, J.2
  • 14
    • 0035324944 scopus 로고    scopus 로고
    • Molecular complexity and its impact on the probability of finding leads for drug discovery
    • M.M. Hann Molecular complexity and its impact on the probability of finding leads for drug discovery J. Chem. Inf. Comput. Sci. 41 2001 856 864
    • (2001) J. Chem. Inf. Comput. Sci. , vol.41 , pp. 856-864
    • Hann, M.M.1
  • 17
    • 79952379571 scopus 로고    scopus 로고
    • IMCA https://www.imca.aps.anl.gov/tiki-index.php?page=IMCA Accessed on 12/11/10
  • 18
    • 0027879008 scopus 로고
    • Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
    • W. Kabsch Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants J. Appl. Crystallogr. 26 1993 795 800
    • (1993) J. Appl. Crystallogr. , vol.26 , pp. 795-800
    • Kabsch, W.1
  • 20
    • 79952378948 scopus 로고    scopus 로고
    • How to Avoid Rediscovering the Known
    • L.C. Kuo How to Avoid Rediscovering the Known Methods Enzymol 493 2011 159 168
    • (2011) Methods Enzymol , vol.493 , pp. 159-168
    • Kuo, L.C.1
  • 21
    • 79952372796 scopus 로고    scopus 로고
    • Medicinal Chemistry-Inspired Fragment-Based Drug Discovery
    • J. Lanter, X. Zhang, and Z. Sui Medicinal Chemistry-Inspired Fragment-Based Drug Discovery Methods Enzymol 493 2011 423 448
    • (2011) Methods Enzymol , vol.493 , pp. 423-448
    • Lanter, J.1    Zhang, X.2    Sui, Z.3
  • 22
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
    • C.A. Lipinski Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Adv. Drug Deliv. Rev. 46 2001 3 26 (Pubitemid 33653411)
    • (2000) Advanced Drug Delivery Reviews , vol.46 , Issue.1-3 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 23
    • 79959821021 scopus 로고    scopus 로고
    • Performance of PILATUS detector technology for long-wavelength macromolecular crystallography
    • J. Marchal, and A. Wagner Performance of PILATUS detector technology for long-wavelength macromolecular crystallography Nucl. Instrum. Methods Phys. Res. A 2010 doi:10.1016/j.nima.2010.06.142
    • (2010) Nucl. Instrum. Methods Phys. Res. A
    • Marchal, J.1    Wagner, A.2
  • 24
    • 58849149063 scopus 로고    scopus 로고
    • Recent and emerging anti-diabetes targets
    • M.L. Mohler Recent and emerging anti-diabetes targets Med. Res. Rev. 29 2009 125 195
    • (2009) Med. Res. Rev. , vol.29 , pp. 125-195
    • Mohler, M.L.1
  • 25
    • 0034476897 scopus 로고    scopus 로고
    • Automated crystal mounting and data collection for protein crystallography
    • S.W. Muchmore Automated crystal mounting and data collection for protein crystallography Structure 8 2000 R243 R246
    • (2000) Structure , vol.8
    • Muchmore, S.W.1
  • 26
    • 77955982439 scopus 로고    scopus 로고
    • Structural biology in fragment-based drug design
    • C.W. Murray, and T.L. Blundell Structural biology in fragment-based drug design Curr. Opin. Struct. Biol. 20 2010 497 507
    • (2010) Curr. Opin. Struct. Biol. , vol.20 , pp. 497-507
    • Murray, C.W.1    Blundell, T.L.2
  • 27
    • 77952716960 scopus 로고    scopus 로고
    • Molecular shape and medicinal chemistry: A perspective
    • A. Nicholls Molecular shape and medicinal chemistry: A perspective J. Med. Chem. 53 2010 3862 3886
    • (2010) J. Med. Chem. , vol.53 , pp. 3862-3886
    • Nicholls, A.1
  • 28
    • 0033773899 scopus 로고    scopus 로고
    • Discovering novel ligands for macromolecules using X-ray crystallographic screening
    • V.L. Nienaber Discovering novel ligands for macromolecules using X-ray crystallographic screening Nat. Biotechnol. 18 2000 1105 1108
    • (2000) Nat. Biotechnol. , vol.18 , pp. 1105-1108
    • Nienaber, V.L.1
  • 29
    • 0031059866 scopus 로고    scopus 로고
    • Processing of X-ray diffraction data collected in oscillation mode
    • DOI 10.1016/S0076-6879(97)76066-X
    • Z. Otwinowski, and W. Minor Processing of X-ray diffraction data collected in oscillation mode C.W. Carter Jr. R.M. Sweet, Methods in Enzymology Vol. 276 1997 Academic Press, San Diego, CA 307 326 (Pubitemid 27085611)
    • (1997) Methods in Enzymology , vol.276 , pp. 307-326
    • Otwinowski, Z.1    Minor, W.2
  • 31
    • 4344625042 scopus 로고    scopus 로고
    • Macromolecular cryocrystallography - Methods for cooling and mounting protein crystals at cryogenic temperatures
    • DOI 10.1016/j.ymeth.2004.03.032, PII S1046202304001227
    • J.W. Pflugrath Macromolecular cryocrystallographyMethods for cooling and mounting protein crystals at cryogenic temperatures Methods 34 2004 415 423 (Pubitemid 39119822)
    • (2004) Methods , vol.34 , Issue.3 , pp. 415-423
    • Pflugrath, J.W.1
  • 32
    • 79952368821 scopus 로고    scopus 로고
    • PXI http://sls.web.psi.ch/view.php/beamlines/px/index.html Accessed on 12/11/10
  • 33
    • 61449224655 scopus 로고    scopus 로고
    • The association of serum adipocyte fatty acid-binding protein with coronary artery disease in Korean adults
    • E.J. Rhee The association of serum adipocyte fatty acid-binding protein with coronary artery disease in Korean adults Eur. J. Endocrinol. 160 2009 165 172
    • (2009) Eur. J. Endocrinol. , vol.160 , pp. 165-172
    • Rhee, E.J.1
  • 35
    • 0035853714 scopus 로고    scopus 로고
    • Robots enter the race to analyze proteins
    • R.F. Service Robots enter the race to analyze proteins Science 292 2001 187 188 (Pubitemid 32295352)
    • (2001) Science , vol.292 , Issue.5515 , pp. 187-188
    • Service, R.F.1
  • 36
    • 79952387370 scopus 로고    scopus 로고
    • SGX
    • SGX. http://www.sgxpharma.com/. now part of Lilly
  • 37
    • 33745188660 scopus 로고    scopus 로고
    • Screening in a spirit haunted world
    • B.K. Shoichet Screening in a spirit haunted world Drug Discov. Today 11 2006 607 615
    • (2006) Drug Discov. Today , vol.11 , pp. 607-615
    • Shoichet, B.K.1
  • 38
    • 0029836953 scopus 로고    scopus 로고
    • Discovering high-affinity ligands for proteins: SAR by NMR
    • DOI 10.1126/science.274.5292.1531
    • S.B. Shuker Discovering high-affinity ligands for proteins: SAR by NMR Science 274 1996 1531 1534 (Pubitemid 26403929)
    • (1996) Science , vol.274 , Issue.5292 , pp. 1531-1534
    • Shuker, S.B.1    Hajduk, P.J.2    Meadows, R.P.3    Fesik, S.W.4
  • 40
    • 79952430797 scopus 로고    scopus 로고
    • Designing a Diverse High-Quality Library for Crystallography-Based FBDD Screening
    • Tounge B.A., and Parker M.H. Designing a Diverse High-Quality Library for Crystallography-Based FBDD Screening Methods Enzymol 493 2011 3 20
    • (2011) Methods Enzymol , vol.493 , pp. 3-20
    • Tounge, B.A.1    Parker, M.H.2
  • 41
    • 65549106974 scopus 로고    scopus 로고
    • Association between adipocyte fatty acid-binding protein levels and childhood obesity in Korean children
    • K.E. Yun Association between adipocyte fatty acid-binding protein levels and childhood obesity in Korean children Metab. Clin. Exp. 58 2009 798 802
    • (2009) Metab. Clin. Exp. , vol.58 , pp. 798-802
    • Yun, K.E.1
  • 42
    • 79952371490 scopus 로고    scopus 로고
    • Zenobia http://www.zenobiatherapeutics.com/home-page.htm Accessed on 12/11/10
    • Zenobia1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.