Assessment of the influence of test characteristics on the clinical and cost impacts of methicillin-resistant Staphylococcus aureus screening programs in US hospitals

Infection Control and Hospital Epidemiology

Volumn 32, Issue 3, 2011, Pages 250-257

  Olchanski, Natalia ^a   Mathews, Charles ^a   Fusfeld, Lauren ^a   Jarvis, William ^b  

^a Boston Healthcare Associates Inc   (United States)

^b Jason and Jarvis Associates   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL TRANSMISSION; HEALTH CARE COST; HIGH RISK PATIENT; HOSPITAL COST; HUMAN; INTENSIVE CARE UNIT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; POLYMERASE CHAIN REACTION; UNITED STATES;

BACTERIOLOGICAL TECHNIQUES; COST-BENEFIT ANALYSIS; HOSPITALS; HUMANS; INTENSIVE CARE UNITS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MODELS, ECONOMIC; POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL INFECTIONS; UNITED STATES;

EID: 79952370986     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/658332     Document Type: Article

References (47)

1. Elixhauser A, Steiner C. Infections with methicillin-resistant Staphylococcus aureus (MRSA) in U.S. Hospitals, 1993-2005. AHRQ Healthcare Cost and Utilization Project Statistical Brief 2007;35.
2. Cosgrove SE, Qi Y, Kaye KS, Harbarth S, Karchmer AW, Carmeli Y. The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Infect Control Hosp Epidemiol 2005;26:166-174. (Pubitemid 40445022)
3. Abramson MA, Sexton DJ. Nosocomial methicillin-resistant and methicillin-susceptible Staphylococcus aureus primary bacteremia: at what costs? Infect Control Hosp Epidemiol 1999;20:408-411.
4. Rao G, Michalczyk P, Nayeem N, Walker G, Wigmore L. Prevalence and risk factors for methicillin-resistant Staphylococcus aureus in adult emergency admissions: a case for screening all patients? J Hosp Infect 2007;66:15-21. (Pubitemid 46657127)
5. Noskin GA, Rubin RJ, Schentag JJ, et al. National trends in Staphylococcus aureus infection rates: impact on economic burden and mortality over a 6-year period (1998-2003). Clin Infect Dis 2007;45:1132-1140.
6. Muto CA, Jernigan JA, Ostrowsky BE, et al. SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus. Infect Control Hosp Epidemiol 2003;24:362-386. (Pubitemid 36612323)
7. Siegel J, Rhinehart E, Jackson M, Chiarello L. Management of multidrug-resistant organisms in healthcare settings: CDC; 2006. Available at http://www.cdc.gov.
8. APIC. Guide to the elimination of methicillin-resistant Staphylococcus aureus (MRSA) transmission in hospital settings APIC; 2007. Available at http://www.apic.org.
9. Harbarth S, Sax H, Uckay I, et al. A predictive model for identifying surgical patients at risk of methicillin-resistant Staphylococcus aureus carriage on admission. J Am Coll Surg 2008;207:683-689.
10. Robicsek A, Beaumont JL, Paule SM, et al. Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med 2008;148:409-418. (Pubitemid 351665440)
11. Peterson LR, Hacek DM, Robicsek A. 5 Million Lives Campaign. Case study: an MRSA intervention at Evanston Northwestern Healthcare. Jt Comm J Qual Patient Saf 2007;33:732-738.
12. Bio-Rad. MRSASelect information sheet; June 2008. Available at http://www.bio-rad.com/Diagnostics/pdfs/-cmd/ MRSASelect%20Product%20Insert%20June%202008.pdf. Accessed February 26, 2010.
13. Becton Dickinson. CHROMAgar MRSA information sheet; 2006. Available at http://www.bd.com/ds/technicalCenter/clsi/clsi-chromagarmrsa.pdf. Accessed February 26, 2010.
14. Nahimana I, Francioli P, Blanc DS. Evaluation of three chromogenic media (MRSA-ID, MRSA-Select and CHROMagar MRSA) and ORSAB for surveillance cultures of methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect 2006;12:1168-1174. (Pubitemid 44762518)
15. Beigi RH, Bunge K, Song Y, Lee BY. Epidemiologic and economic effect of methicillin-resistant Staphylococcus aureus in obstetrics. Obstet Gynecol 2009;113:983-991.
16. Clancy M, Graepler A, Wilson M, Douglas I, Johnson J, Price CS. Active screening in high-risk units is an effective and cost-avoidant method to reduce the rate of methicillin-resistant Staphylococcus aureus infection in the hospital. Infect Control Hosp Epidemiol 2006;27:1009-1017. (Pubitemid 44670975)
17. Noskin GA, Rubin RJ, Schentag JJ, et al. Budget impact analysis of rapid screening for Staphylococcus aureus colonization among patients undergoing elective surgery in US hospitals. Infect Control Hosp Epidemiol 2008;29:16-24. (Pubitemid 351267769)
18. Shrestha NK, Shermock KM, Gordon SM, et al. Predictive value and cost-effectiveness analysis of a rapid polymerase chain reaction for preoperative detection of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol 2003;24:327-333. (Pubitemid 36612317)
19. Cooper BS, Stone SP, Kibbler CC, et al. Systematic review of isolation policies in the hospital management of methicillinresistant Staphylococcus aureus: a review of the literature with epidemiological and economic modelling. Health Technol Assess 2003;7:1-194.
20. Raboud J, Saskin R, Simor A, et al. Modeling transmission of methicillin-resistant Staphylococcus aureus among patients admitted to a hospital. Infect Control Hosp Epidemiol 2005;26:607-615. (Pubitemid 41073400)
21. Ismail NA, Pettitt AN. Smoothing a discrete hazard function for the number of patients colonized with methicillin-resistant Staphylococcus aureus in an intensive care unit. Stat Med 2004;23:1247-1258. (Pubitemid 38514822)
22. Drovandi CC, Pettitt AN. Multivariate Markov process models for the transmission of methicillin-resistant Staphylococcus aureus in a hospital ward. Biometrics 2008;64:851-859.
23. McBryde ES, Pettitt AN, McElwain DL. A stochastic mathematical model of methicillin resistant Staphylococcus aureus transmission in an intensive care unit: predicting the impact of interventions. J Theor Biol 2007;245:470-481. (Pubitemid 46365751)
24. Jonas S. An introduction to the U.S. health care system. New York, Springer; 2003.
25. American Hospital Association. Fast facts on US hospitals. Available at http://www.aha.org/aha/resource-center/Statistics-and-Studies/fast-facts.html. Accessed January 16, 2009.
26. Jarvis WR, Schlosser J, Chinn RY, Tweeten S, Jackson M. National prevalence of methicillin-resistant Staphylococcus aureus in inpatients at US health care facilities, 2006. Am J Infect Control 2007;35:631-637.
27. Papia G, Louie M, Tralla A, Johnson C, Collins V, Simor AE. Screening high-risk patients for methicillin-resistant Staphylococcus aureus on admission to the hospital: is it cost effective? Infect Control Hosp Epidemiol 1999;20:473-477.
28. Duke EM. Report to Congress: The Critical Care Workforce: A Study of the Supply and Demand for Critical Care Physicians: HRSA; 2006. Available at ftp://ftp.hrsa.gov/bhpr/nationalcenter/criticalcare.pdf.
29. Hidron AI, Kourbatova EV, Halvosa JS, et al. Risk factors for colonization with methicillin-resistant Staphylococcus aureus (MRSA) in patients admitted to an urban hospita: emergence of community-associated MRSA nasal carriage. Clin Infect Dis 2005;41:159-166. (Pubitemid 40962495)
30. Cosgrove SE, Sakoulas G, Perencevich EN, Schwaber MJ, Karchmer AW, Carmeli Y. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis 2003;36:53-59. (Pubitemid 36099097)
31. Jernigan JA, Pullen AL, Flowers L, Bell M, Jarvis WR. Prevalence of and risk factors for colonization with methicillin-resistant Staphylococcus aureus at the time of hospital admission. Infect Control Hosp Epidemiol 2003;24:409-414. (Pubitemid 36818508)
32. Buhlmann M, Bogli-Stuber K, Droz S, Muhlemann K. Rapid screening for carriage of methicillin-resistant Staphylococcus aureus by PCR and associated costs. J Clin Microbiol 2008;46:2151-2154.
33. Back NA, Linnemann CC Jr, Staneck JL, Kotagal UR. Control of methicillin-resistant Staphylococcus aureus in a neonatal intensive-care unit: use of intensive microbiologic surveillance and mupirocin. Infect Control Hosp Epidemiol 1996;17:227-231. (Pubitemid 126468081)
34. Coello R, Glynn JR, Gaspar C, Picazo JJ, Fereres J. Risk factors for developing clinical infection with methicillin-resistant Staphylococcus aureus (MRSA) amongst hospital patients initially only colonized with MRSA. J Hosp Infect 1997;37:39-46. (Pubitemid 27434527)
35. Jernigan JA, Clemence MA, Stott GA, et al. Control of methicillin-resistant Staphylococcus aureus at a university hospital: one decade later. Infect Control Hosp Epidemiol 1995;16:686-696.
36. Roccaforte JS, Bittner MJ, Stumpf CA, Preheim LC. Attempts to eradicate methicillin-resistant Staphylococcus aureus colonization with the use of trimethoprim-sulfamethoxazole, rifampin, and bacitracin. Am J Infect Control 1988;16:141-146.
37. Takahashi N, Nishida H, Kato H, Imanishi K, Sakata Y, Uchiyama T. Exanthematous disease induced by toxic shock syndrome toxin 1 in the early neonatal period. Lancet 1998;351:1614-1619. (Pubitemid 28252177)
38. Muto CA. Designing a Program to Eliminate MRSA Transmission Part I: Making the Clinical Case. Presented at APIC, December 6, 2006.
39. Jernigan JA, Titus MG, Groschel DH, Getchell-White S, Farr BM. Effectiveness of contact isolation during a hospital outbreak of methicillin-resistant Staphylococcus aureus. Am J Epidemiol 1996;143:496-504. (Pubitemid 26085080)
40. Huang SS, Platt R. Risk of methicillin-resistant Staphylococcus aureus infection after previous infection or colonization. Clin Infect Dis 2003;36:281-285. (Pubitemid 36169662)
41. Marshall C, Spelman D, Harrington G, McBryde E. Daily hazard of acquisition of methicillin-resistant Staphylococcus aureus infection in the intensive care unit. Infect Control Hosp Epidemiol 2009;30:125-129.
42. Chaberny IF, Ziesing S, Mattner F, et al. The burden of MRSA in four German university hospitals. Int J Hyg Environ Health 2005;208:447-453. (Pubitemid 41527201)
43. Kaye KS, Engemann JJ, Mozaffari E, Carmeli Y. Reference group choice and antibiotic resistance outcomes. Emerg Infect Dis 2004;10:1125-1128. (Pubitemid 38697709)
44. Stone PW, Larson E, Kawar LN. A systematic audit of economic evidence linking nosocomial infections and infection control interventions: 1990-2000. Am J Infect Control 2002;30:145-152.
45. FitzGerald S. More hospitals fight MRSA with universal screening: are "search and destroy" methods the right call? ACP Hospitalist 2007.
46. Levenson D. The path to better MRSA control. Clinical Laboratory News 2007;33:8.
47. Paule SM, Hacek DM, Kufner B, et al. Performance of the BD GeneOhm methicillin-resistant Staphylococcus aureus test before and during high-volume clinical use. J Clin Microbiol 2007;45:2993-2998. (Pubitemid 47417345)