Successful intraoperative reversal of heparin with factor VII in a patient with protamine reaction

Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery

Volumn 6, Issue 1, 2011, Pages 48-50

  Chen, Kuan Chin Jean ^a   Payne, Darrin ^a   Lazo Langner, Alejandro ^b   Ross, Ian ^b   Kiaii, Bob ^c  

^a Division of Cardiac Surgery   (Canada)

^b WESTERN UNIVERSITY   (Canada)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Aortic dissection; Heparin; Protamine reaction; Recombinant factor VIIa

Indexed keywords

HEPARIN; PROTAMINE SULFATE; RECOMBINANT BLOOD CLOTTING FACTOR 7A;

ABDOMINAL RADIOGRAPHY; AGED; AORTA DISSECTION; ARTICLE; BLEEDING; BLOOD CLOTTING DISORDER; CARDIOPULMONARY BYPASS; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; EMERGENCY SURGERY; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE FUNCTION; HEART SURGERY; HUMAN; HYPOTENSION; MALE; PELVIS RADIOGRAPHY; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SIDE EFFECT; THORAX PAIN; THORAX RADIOGRAPHY;

EID: 79952369110     PISSN: 15569845     EISSN: 15590879     Source Type: Journal    
DOI: 10.1097/IMI.0b013e31820ba9ff     Document Type: Article

References (3)

1. Lauritzen B, Hedner U, Johansen PB, et al. Recombinant human factor VIIa and a factor VIIa-analogue reduces heparin and low molecular weight heparin (LMWH)-induced bleeding in rats. J Thromb Haemost. 2008;6:804-811. (Pubitemid 351524541)
2. Collins C, A O'Donnell. Does an allergy to fish pre-empt an adverse protamine reaction? A case report and a literature review. Perfusion. 2008;23:369-372.
3. Wahed S, Karagounis AP, Niranjan G, Kanagasabay R. Successful graft patency after factor VIIa use for bleeding in coronary artery surgery: An unusual complication of a coronary artery bypass surgery. J Card Surg. 2007;22:424-427. (Pubitemid 47353023)