Synthesis and in vitro anti-HSV-1 activity of a novel Hsp90 inhibitor BJ-B11

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 6, 2011, Pages 1675-1677

  Ju, Huai Qiang ^a   Xiang, Yang Fei ^a   Xin, Bao Juan ^b   Pei, Ying ^a   Lu, Jia Xin ^a   Wang, Qiao Li ^a   Xia, Min ^a   Qian, Chui Wen ^a   Ren, Zhe ^a   Wang, Sha Yan ^a   Wang, Yi Fei ^a   Xing, Guo Wen ^b  

^a JINAN UNIVERSITY   (China)

^b BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Antivirals; Herpes simplex virus; Hsp90 inhibitor

Indexed keywords

2 (4 ACETYLOXYCYCLOHEXYLAMINO) 4 (3,6,6 TRIMETHYL 4 OXO 4,5,6,7 TETRAHYDRO 1H INDAZOL 1 YL)BENZAMIDE; 4 HYDRAZINO 2 (4 HYDROXYCYCLOHEXYLAMINO)BENZONITRILE; ACICLOVIR; ANTILEUKEMIC AGENT; ANTIVIRUS AGENT; BJ B 11; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; SNX 2112; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; COXSACKIE VIRUS B3; CYTOPATHOGENIC EFFECT; DRUG BLOOD LEVEL; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; IN VITRO STUDY; INFLUENZA VIRUS A H1N1; NONHUMAN; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS RESISTANCE;

ANTIVIRAL AGENTS; BENZAMIDES; HERPESVIRUS 1, HUMAN; HSP90 HEAT-SHOCK PROTEINS; INDAZOLES; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION;

COXSACKIEVIRUS; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2; HUMAN RESPIRATORY SYNCYTIAL VIRUS; ORTHOMYXOVIRIDAE; SIMPLEXVIRUS;

EID: 79952362910     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.01.098     Document Type: Article

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