A stereoselective approach to 6-alkylated piperidinone & 2-piperidine via three-component vinylogous Mannich reactions (VMR) and a concise synthesis of (S)-anabasine

Tetrahedron Letters

Volumn 52, Issue 14, 2011, Pages 1549-1552

  Yang, Yang ^a   Phillips, Dean P ^a   Pan, Shifeng ^a  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

Anabasine; Asymmetric synthesis; Piperidine; Piperidinone; Vinylogous Mannich reaction

Indexed keywords

ANABASINE; PIPERIDINE; PIPERIDONE DERIVATIVE; SILANE DERIVATIVE; SILYL KETENE ACETAL; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; MANNICH REACTION; STEREOCHEMISTRY; VINYLOGOUS MANNICH REACTION;

EID: 79952362789     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.01.090     Document Type: Article

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