Antiviral agents 3. Discovery of a novel small molecule non-nucleoside inhibitor of Hepatitis B Virus (HBV)

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 6, 2011, Pages 1644-1648

  Crosby, Ian T ^a   Bourke, David G ^a   Jones, Eric D ^a   Jeynes, Tyrone P ^a   Cox, Susan ^b,d   Coates, Jonathan A V ^b,c   Robertson, Alan D ^b,e  

^a MONASH UNIVERSITY   (Australia)

^b Zenyth Therapeutics Limited Australia   (Australia)

^c Avexa Ltd   (Australia)

^d Biota Holdings Ltd   (Australia)

^e Pharmaxis Ltd   (Australia)

Author keywords

Anti HBV activity; AZT resistant HBV; Conocurvone; Hepatitis inhibition; Naphthoquinone trimers

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 8 HYDROXY 3H NAPHTHO[2,1B]PYRAN 7,10 DIONE; 8 HYDROXY 3H NAPHTHO[2,1B]PYRAN 7,10 DIONE DERIVATIVE; 9 HYDROXY 3H NAPHTHO[2,1B]PYRAN 7,10 DIONE; ADEFOVIR DIPIVOXIL; ANTIVIRUS AGENT; ENTECAVIR; HEPATITIS B VACCINE; HYDROXYNAPHTHOPYRANQUINONE; LAMIVUDINE; PEGINTERFERON ALPHA2A; PENCICLOVIR; RECOMBINANT ALPHA2B INTERFERON; SMALL MOLECULE NON NUCLEOSIDE INHIBITOR; TELBIVUDINE; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; DRUG SCREENING; DRUG SYNTHESIS; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; NONHUMAN; VIRUS CELL INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS RESISTANCE;

ANIMALS; ANTIVIRAL AGENTS; DRUG DISCOVERY; HEPATITIS B VIRUS;

HEPATITIS B VIRUS;

EID: 79952361480     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.01.109     Document Type: Article

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