The presence of leukocytes in ex vivo assays significantly increases the 50-percent inhibitory concentrations of artesunate and chloroquine against Plasmodium vivax and Plasmodium falciparum

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 3, 2011, Pages 1300-1304

  Kaewpongsri, S ^a   Sriprawat, K ^a   Suwanarusk, R ^b   Kyle, D E ^c   Lek Uthai, U ^d   Leimanis, M ^a   Lwin, K M ^a   Phyo, A P ^a   Zwang, J ^a   Russell, B ^b   Nosten, F ^a,d,e   Renia, L ^b  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b AGENCY FOR SCIENCE   (Singapore)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d MAHIDOL UNIVERSITY   (Thailand)

^e JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; ARTESUNATE; CHLOROQUINE; DIHYDROARTEMISININ; HEMOZOIN;

ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; ERYTHROCYTE; EX VIVO STUDY; GRANULOCYTE; IC 50; KRUSKAL WALLIS TEST; LEUKOCYTE; LEUKOCYTE COUNT; LYMPHOCYTE; MEROZOITE; MONOCYTE; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PHARMACODYNAMICS; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PRIORITY JOURNAL; WILCOXON SIGNED RANKS TEST;

ANTIMALARIALS; ARTEMISININS; CHLOROQUINE; HUMANS; INHIBITORY CONCENTRATION 50; LEUKOCYTES; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX;

EID: 79952347602     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01103-10     Document Type: Article

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