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70350786389
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Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): A randomised, doubleblind, placebo-controlled trial
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Comi G, Martinelli V, Rodegher M, Moiola L, Bajenaru O, Carra A, et al. Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, doubleblind, placebo-controlled trial. Lancet 2009; 374: 1503-11. [Erratum in: Lancet 2010; 375: 1436].
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0034727059
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Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis
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CHAMPS Study Group
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Jacobs LD, Beck RW, Simon J, Kinkel RP, Brownscheidle CM, Murray TJ, et al. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group. N Engl J Med 2000; 34: 898-904.
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Effect of early interferon treatment on conversion to definite multiple sclerosis: A randomised study
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Comi G, Filippi M, Barkhof F, Durrelli L, Edan G, Fernández O, et al. Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study. Lancet 2001; 357: 1576-82. (Pubitemid 32488815)
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4
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70449713830
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Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial
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BENEFIT Study Group
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Kappos L, Freedman MS, Polman CH, Edan G, Hartung HP, Miller DH, et al. BENEFIT Study Group. Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial. Lancet Neurol 2009; 8: 987-97.
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65549144672
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NORdic trial of oral methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): A randomised, placebo-controlled trial
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Sorensen PS, Mellgren SI, Svenningsson A, Elovaara I, Frederiksen JL, Beiske AG, et al. NORdic trial of oral methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): a randomised, placebo-controlled trial. Lancet Neurol 2009; 8: 519-29.
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6
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77953618723
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Methylprednisolone in combination with interferon beta-1a for relapsing-remitting multiple sclerosis (MECOMBIN study): A multicentre, double-blind, randomised, placebo-controlled, parallel-group trial
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Ravnborg M, Sorensen PS, Andersson M, Celius EG, Jongen PJ, Elovaara I, et al. Methylprednisolone in combination with interferon beta-1a for relapsing-remitting multiple sclerosis (MECOMBIN study): a multicentre, double-blind, randomised, placebo-controlled, parallel-group trial. Lancet Neurol 2010; 9: 672-80.
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7
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62149143732
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Results of the Avonex Combination Trial (ACT) in relapsing-remitting MS
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Cohen JA, Imrey PB, Calabresi PA, Edwards KR, Eickenhorst T, Felton WL III, et al. Results of the Avonex Combination Trial (ACT) in relapsing-remitting MS. Neurology 2009; 72: 535-41.
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8
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79952332352
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No beneficial effect of simvastatin as add-on therapy to interferon-beta-1a for the treatment of relapsing-remitting multiple sclerosis: Results of a large double blind, randomised, placebo-controlled trial
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Sorensen PS, Lycke J, Erälinna JP, Edland A, Wu X, Frederiksen J, et al. No beneficial effect of simvastatin as add-on therapy to interferon-beta-1a for the treatment of relapsing-remitting multiple sclerosis: results of a large double blind, randomised, placebo-controlled trial. 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Gothenburg, Sweden, 13-16 October 2010.
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26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Gothenburg, Sweden, 13-16 October 2010
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Sorensen, P.S.1
Lycke, J.2
Erälinna, J.P.3
Edland, A.4
Wu, X.5
Frederiksen, J.6
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9
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60049089535
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Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: A retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study
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Havrdova E, Galetta S, Hutchinson M, Stefoski D, Bates D, Polman CH, et al. Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study. Lancet Neurol 2009; 8: 254-60.
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10
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79959971308
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Overview of clinical outcomes in cases of natalizumab-associated progressive multifocal leukoencephalopathy
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abstract 112
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Vermersch P, Foley J, Gold R, Kappos L, Olsson T, Bozic C, et al. Overview of clinical outcomes in cases of natalizumab-associated progressive multifocal leukoencephalopathy. Mult Scler 2010; 16: S7-39 [abstract 112].
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11
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78650138283
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Alemtuzumab long-term safety and efficacy: Five years of the CAMMS223 Trial
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on behalf of the CAMMS223 Study Group abstract P410
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Coles A, on behalf of the CAMMS223 Study Group. Alemtuzumab long-term safety and efficacy: five years of the CAMMS223 Trial. Mult Scler 2010; 16: S41-196 [abstract P410].
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B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
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Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, et al. HERMES Trial Group. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med 2008; 358: 676-88. (Pubitemid 351240747)
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Sarkar, N.9
Agarwal, S.10
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Smith, C.H.12
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13
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79952322244
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Daclizumab treatment and CD56bright NK cell counts independently predict being lesion-free on brain MRI scans: Results from the phase 2 CHOICE trial
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abstract P557
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Riester K, Sheridan J, Zhang Y, O'Neil G, Elkins J. Daclizumab treatment and CD56bright NK cell counts independently predict being lesion-free on brain MRI scans: results from the phase 2 CHOICE trial. Mult Scler 2010; 16: S41-196 [abstract P557].
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14
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79952355430
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Magnetic resonance imaging (MRI) efficacy of ofatumumab in relapsing-remitting multiple sclerosis (RRMS) -24-week results of a phase II study
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Sorensen PS, Drulovic J, Havrdova E, Lisby S, Graff O, Shackelford S. Magnetic resonance imaging (MRI) efficacy of ofatumumab in relapsing-remitting multiple sclerosis (RRMS) -24-week results of a phase II study. 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Gothenburg, Sweden, 13-16 October 2010.
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26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Gothenburg, Sweden, 13-16 October 2010
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Sorensen, P.S.1
Drulovic, J.2
Havrdova, E.3
Lisby, S.4
Graff, O.5
Shackelford, S.6
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15
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79952335307
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Natural history of EDSS, HRQoL and QALY progression in relapsing-onset MS in Nova Scotia, 1979-1998
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abstract P608
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Brown MG, Skedgel C, Andreou P, Kirby S, Murray TJ. Natural history of EDSS, HRQoL and QALY progression in relapsing-onset MS in Nova Scotia, 1979-1998. Mult Scler 2010; 16: S41-196 [abstract P608].
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Brown, M.G.1
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16
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79952353866
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TYSEDMUS: Observational prospective follow-up study of patients with MS and treated with natalizumab in France using the French EDMUS (European Database for Multiple Sclerosis) network
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abstract 67
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Vukusic S, Passante N, Abdelali A, Dufour M, Frangoulis B, Van Ganse E. TYSEDMUS: observational prospective follow-up study of patients with MS and treated with natalizumab in France using the French EDMUS (European Database for Multiple Sclerosis) network. Mult Scler 2010; 16: S7-39 [abstract 67].
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17
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37749016994
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Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: Treatment response factors in a 5 year follow-up observational study of 100 consecutive patients
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Le PE, Leray E, Taurin G, Coustans M, Chaperon J, Morrissey SP, et al. Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: treatment response factors in a 5 year follow-up observational study of 100 consecutive patients. J Neurol Neurosurg Psychiatry 2008; 79: 52-6.
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18
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46849091551
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Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis
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DOI 10.1177/1352458507085759
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Vollmer T, Panitch H, Bar-Or A, Dunn J, Freedman MS, Gazda SK, et al. Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis. Mult Scler 2008; 14: 663-70. (Pubitemid 351954409)
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Gazda, S.K.6
Campagnolo, D.7
Deutsch, F.8
Arnold, D.L.9
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19
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79952345289
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Cytotoxic therapeutic agents in MS
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Edan G. Cytotoxic therapeutic agents in MS. Mult Scler 2010; 16: S7-39 [abstract 110].
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Edan, G.1
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20
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77951828930
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Evidence report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
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Marriott JJ, Miyasaki JM, Gronseth G, O'Connor PW. Evidence report: the efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2010; 74: 1463-70.
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Marriott, J.J.1
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21
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33644605483
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Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
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Yousry TA, Major EO, Ryschkewitsch C, Fahle G, Fischer S, Hou J, et al. Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy. N Engl J Med 2006; 354: 924-33.
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Yousry, T.A.1
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Fischer, S.5
Hou, J.6
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22
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84861080332
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Factors associated with anti-JCV antibody prevalence in a large cohort of natalizumab-treated MS patients
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abstract 138
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Subramanyam M, Plavina T, Simon K, Wilson E, Berman M, Schlain B, et al. Factors associated with anti-JCV antibody prevalence in a large cohort of natalizumab-treated MS patients. Mult Scler 2010; 16: S197-352 [abstract 138].
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Subramanyam, M.1
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23
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79952318554
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Phase II trial of firategrast shows that oral antialpha4 therapy can suppress new MRI lesions in relapsing-remitting multiple sclerosis
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abstract 113
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Miller D, Weber T, Montalban X, Grove R, Dua P, Wardell C, et al. Phase II trial of firategrast shows that oral antialpha4 therapy can suppress new MRI lesions in relapsing-remitting multiple sclerosis. Mult Scler 2010; 16: S7-39 [abstract 113].
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Miller, D.1
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24
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78650159514
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Efficacy and safety of ocrelizumab in patients with relapsing-remitting multiple sclerosis: Results of a phase II randomised placebo-controlled multicentre trial
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abstract 114
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Kappos L, Calabresi P, O'Connor P, Bar-Or A, Li D, Barkhof F. Efficacy and safety of ocrelizumab in patients with relapsing-remitting multiple sclerosis: results of a phase II randomised placebo-controlled multicentre trial. Mult Scler 2010; 16: S7-39 [abstract 114].
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Kappos, L.1
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Barkhof, F.6
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