Engineered picornavirus VPg-RNA substrates: Analysis of a tyrosyl-RNA phosphodiesterase activity

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Rozovics, Janet M ^a   Virgen Slane, Richard ^a   Semler, Bert L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' TYROSYL RNA PHOSPHODIESTERASE; GENOMIC RNA; PHOSPHODIESTERASE; UNCLASSIFIED DRUG; VIRAL PROTEIN GENOME LINKED; VIRUS MESSENGER RNA; VIRUS PROTEIN; VIRUS RNA; CELL EXTRACT; MUTANT PROTEIN; RIBONUCLEASE T1; TYROSINE; VPG PROTEIN, POLIOVIRUS;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME ENGINEERING; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; GENETIC ENGINEERING; HELA CELL; HOST CELL; HUMAN; HUMAN CELL; HUMAN RHINOVIRUS; NONHUMAN; PICORNAVIRUS; POLIOMYELITIS; POLIOMYELITIS VIRUS; PROCESS DEVELOPMENT; PROTEIN FUNCTION; PROTEIN RNA BINDING; PROTEIN SYNTHESIS; RNA CLEAVAGE; RNA REPLICATION; TRANSLATION REGULATION; VIRION; VIRUS GENOME; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; ISOTOPE LABELING; METABOLISM; MOLECULAR GENETICS; RHINOVIRUS;

HUMAN RHINOVIRUS SP.; PICORNAVIRIDAE; POLIOVIRUS;

AMINO ACID SEQUENCE; CELL EXTRACTS; ENZYME ASSAYS; GENETIC ENGINEERING; GENOME, VIRAL; HELA CELLS; HUMANS; ISOTOPE LABELING; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PHOSPHORIC DIESTER HYDROLASES; POLIOVIRUS; RHINOVIRUS; RIBONUCLEASE T1; RNA, VIRAL; SUBSTRATE SPECIFICITY; TYROSINE; VIRAL PROTEINS; VIRION;

EID: 79952337082     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016559     Document Type: Article

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