Lipase-catalyzed alcoholytic resolution of (R,S)-flurbiprofenyl azolides for preparation of (R)-NO-flurbiprofen ester prodrugs

Process Biochemistry

Volumn 46, Issue 4, 2011, Pages 960-965

  Ciou, Jyun Fen ^a   Wang, Pei Yun ^a   Wu, An Chi ^a   Tsai, Shau Wei ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

(R) NO flurbiprofen ester prodrugs; (R,S) Flurbiprofenyl azolides; (S) Flurbiprofen; Alcoholysis; Kinetic resolution; Lipases

Indexed keywords

(R)-NO-FLURBIPROFEN ESTER PRODRUGS; (R,S)-FLURBIPROFENYL AZOLIDES; ALCOHOLYSIS; FLURBIPROFEN; KINETIC RESOLUTION;

CATALYSIS; CHIRALITY; ENANTIOMERS; ENZYME ACTIVITY; ESTERIFICATION; ESTERS; ETHERS; HYDROLASES; LIPASES; RATE CONSTANTS; SYNTHESIS (CHEMICAL); THERMOANALYSIS;

ENANTIOSELECTIVITY;

CANDIDA;

EID: 79952315277     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2011.01.017     Document Type: Article

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