Effect of Rumex steudelii methanolic root extract on ovarian folliculogenesis and uterine histology in female albino rats

African Health Sciences

Volumn 10, Issue 4, 2010, Pages 353-361

  Solomon, T ^a   Largesse, Z ^a   Mekbeb, A ^a   Eyasu, M ^a   Asfaw, D ^b  

^a ADDIS ABABA UNIVERSITY   (Ethiopia)

^b ETHIOPIAN PUBLIC HEALTH INSTITUTE   (Ethiopia)

Author keywords

Antifertility; Corpus luteum; Endometrium; Folliculogenesis; Ovarian follicles; Ovary; Rats; Rumex steudelii; Uterus

Indexed keywords

CONTRACEPTIVE AGENT; METHANOL; PLANT EXTRACT; RUMEX STEUDELII EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTRACEPTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SCREENING; ESTRUS CYCLE; FEMALE; NONHUMAN; OVARY FOLLICLE DEVELOPMENT; PLANT ROOT; RAT; RUMEX; RUMEX STEUDELII; TREATMENT DURATION; UTERUS CONTRACTION; UTERUS FUNCTION; UTERUS WEIGHT;

ANIMALS; CONTRACEPTIVE AGENTS, FEMALE; FEMALE; METHANOL; MICROSCOPY; ORGAN SIZE; OVARIAN FOLLICLE; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, WISTAR; RUMEX; UTERUS;

EID: 79952305291     PISSN: 16806905     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Maurya R, Srivastava S, Kulshreshta DK, Gupta CM. Traditional remedies for fertility regulation. Current Medicinal Chemistry. 2004; 11: 1431-1450.
2. Gebrie E, Makonnen E, Debella A, Zerihun L. Phytochemical screening and pharmacological evaluations for the antifertility effect of the methanolic root extract of Rumex steudelii. Journal of Ethnopharmacology. 2005; 96:139-143.
3. Desta, B. Ethiopian Traditional Herbal Drugs. Part III: Antifertility activities of 70 medicinal plants. Journal of Ethnopharmacology. 1994; 44: 199-209.
4. Gebrie E, Makonnen E, Zerihun L, Debella A. The possible mechanisms for the antifertility action of methanolic rootextract of Rumex steudelii. African health science. 2005; 5(2): 119-125
5. Bolon B, Bucci TJ, Warbritton AR, Chen JJ, Mattison DR, Heindel JJ. Differential follicle counts as a screen for chemically induced ovarian toxicity in mice: Results from continuous breeding bioassays. Fundamental Applied Toxicology. 1997; 39: 1-10
6. Cooper RL, Goldman JM, Vandenbergh JG. Monitoring of the estrous cycle in the laboratory rodent by vaginal lavage. In: Heindel JJ, Chapin RE, editors. Methods in toxicology: female reproductive toxicology. San Diego: Academic press; 1993. P. 45-56.
7. Rama Krishna Murthy D, Madhusudan Reddy C, Patil SB. Effect of benzene extract of Hibiscus rosa sinesis on the estrous cycle and ovarian activity in albino mice. Biology and Pharmaceutical Bulletin. 1997; 20 (7): 756
8. Andriana DP, Thomas HU, Benjamin RF, Peter LG, Nicholas, TL, Ken MB. Bisphenol Ainduced increase in uterine weight and alterations n uterine morphology in ovariectomized B6C3F1 Mice: Role of Estrogen Receptor. Toxicological science. 2000; 56: 332-339.
9. Lundy T, Smith P, O' Connell A, Hudson NL, Mc Natty KP. Populations of granulosa cells in small follicles of the sheep ovary. Journal of Reproduction and fertility. 1999; 155: 251-262.
10. Osman P. Rate and course of atresia during follicular development in the adult cycling rat. Journal of reproduction and fertility, 1985; 73: 261-270.
11. Engelbregt MJT, Van Weissenbruch MM, Popp- Snijders C, Delemarre-Van de Waal HA. Delayed first cycle in intrauterine growth-related and postnatally undernourished female rats: Follicular growth and ovulation after stimulation with pregnant mare serum gonadotropin at first cycle. Journal of endocrinology. 2002; 173: 297- 304.
12. Cortvrindt R, Smith. Invitro follicle growth: Achievements in Mammalian species. Reproduction of Domestic Animals. 2001; 36: 3-9.
13. Shivalingappa H, Satyanarayan ND, Purohit MG, Sharanabasappa A, Patil SB. Effect of ethanol extract of Rivea hypocrateriformis on the estrous cycle of the rat. Journal of Ethnopharmacology. 2002; 82: 11-17.
14. Gore-Langton RE, Armstrong DT. Follicular steroidogenesis and its control. In: Knobil E, Neil J, editors. The physiology of reproduction. New York: Raven press; 1988. p. 331-385.
15. Sharanabasappa A, Vijayakumar B, Sarasweit B. Effect of Momordica charantia seed extracts on ovarian and uterine activities in Albino Rats. Pharmaceutical Biology. 2002; 40 (7): 501-507.
16. Dixit VP. Effect of chronically administered Malva Viscus Conzattii flower extract on the female genital tract of gerbil, Merionis hurrianae, Jerdon. Indian Journal of Experimental Biology.1977; 15 (8): 1650-1652.
17. Carroll WR. Variation in the water content of the rat uterus during continuous estrogenic treatment. Endocrinology.1945; 36:266-271.
18. Pal SS. Fertility control of female through Sesbania Sesban Seeds. Journal of Research and Education in Indian Medicine. 1990; 9 (4): 27 -32.