Analysis of separation methods for isopropanol recovery in the celecoxib process

AIChE Annual Meeting, Conference Proceedings

Volumn , Issue , 2008, Pages

  Slater, C Stewart ^a   Savelski, Mariano ^a   Hounsell, Gregory ^b   Pilipauskas, Daniel ^b   Urbanski, Frank ^b  

^a ROWAN UNIVERSITY   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE INGREDIENTS; CELECOXIB; CONCEPTUAL STUDY; DISSOLVED SOLIDS; GREEN DESIGNS; GREEN ENGINEERING; ISO-PROPANOLS; MANUFACTURING OPERATIONS; MANUFACTURING PROCESS; MEMBRANE PERVAPORATION; MEMBRANE-BASED PROCESS; PARTNERSHIP PROGRAMS; PUERTO RICO; REACTIVE DISTILLATIONS; RECOVERY AND PURIFICATIONS; ROWAN UNIVERSITY; SEPARATION METHODS; SOLVENT RECOVERY; WASTE MINIMIZATION; WASTE STREAM;

ADSORPTION; COMPUTER SIMULATION; CONSERVATION; DISTILLATION; ENVIRONMENTAL IMPACT; ETHANOL; EVAPORATION; MANUFACTURE; METHANOL; MOLECULAR SIEVES; PERVAPORATION; PURIFICATION; SIEVES;

RECOVERY;

EID: 79952295626     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (8)

1. Anon, "Students, Pfizer improve pharmaceutical process", Reliable Plant, www.reliableplant.com/article.asp?articleid=12078, June 2008.
2. Scot, A, "Pfizer seeks to reduce solvent use," Chemical Week, http://www.chemweek.com/people-and-business/green-issues/12391.html, June 2008.
3. Flavell-White, C, "Rowan University to cut Pfizer's solvent use," TCE Today, www.tcetoday.com/tcetoday/NewsDetail.aspx?nid=10530 June 2008.
4. Slater, C.S.; M. Savelski, B. Lefebvre, S. Farrell, R. Hesketh, "Using the Rowan University engineering clinic model to implement green engineering partnerships with the pharmaceutical industry," 12th Annual ACS Green Chemistry & Engineering Conference, Washington, DC, June 2008.
5. th Annual ACS Green Chemistry & Engineering Conference, Washington, DC, June 2008.
6. Furiato, A.; K. Lynch, T. Moroz, M.J. Savelski, C.S. Slater, "Green engineering design for the recovery of solvents in API manufacturing," 12th Annual ACS Green Chemistry & Engineering Conference, Washington, DC, June 2008.
7. Qiao, X.; Chung, T.; Guo, W.F.; Matsuura, T.; Teoh, M.M., "Dehydration of isopropanol and its comparison with dehydration of butanol isomers from thermodynamic and molecular aspects". Journal of Membrane Science (2005), 252, 37-49.
8. Van Hoof, V.; Van den Abeele, L.; Buekenhoudt, A.; Dotremont, C.; Leysen, R. Economic comparison between azeotropic distillation and different hybrid systems combining distillation with pervaporation for the dehydration of isopropanol. Separation and Purification Technology (2004), 37(1), 33-49.