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Volumn 65, Issue 4, 2011, Pages 407-414

Effect of Hypoxia on Endothelial Nitric Oxide Synthase, NO Production, Intracellular Survival Signaling (p-ERK1/2 and p-AKT) and Apoptosis in Human Term Trophoblast

Author keywords

Apoptosis; ENOS; Hypoxia; Signal transduction; Trophoblast

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; OXYGEN; PROTEIN KINASE B;

EID: 79952295070     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2010.00886.x     Document Type: Article
Times cited : (9)

References (31)
  • 1
    • 0026573750 scopus 로고
    • Intrauterine growth retardation: definition, classification, and etiology
    • Pollack RN, Divon MY: Intrauterine growth retardation: definition, classification, and etiology. Clin Obstet Gynecol 1992; 35:99-107.
    • (1992) Clin Obstet Gynecol , vol.35 , pp. 99-107
    • Pollack, R.1    Divon, M.2
  • 2
    • 0027359286 scopus 로고
    • The intrauterine origins of cardiovascular disease
    • Barker DJ: The intrauterine origins of cardiovascular disease. Acta Paediatr Suppl 1993; 82(Suppl. 391):93-99.
    • (1993) Acta Paediatr Suppl , vol.82 , Issue.SUPPL. 391 , pp. 93-99
    • Barker, D.1
  • 4
    • 2442481955 scopus 로고    scopus 로고
    • Prognostic value of placental ultrasound in pregnancies complicated by absent end-diastolic flow velocity in the umbilical arteries
    • Viero S, Chaddha V, Alkazaleh F, Simchen MJ, Malik A, Kelly E, Windrim R, Kingdom JC: Prognostic value of placental ultrasound in pregnancies complicated by absent end-diastolic flow velocity in the umbilical arteries. Placenta 2004; 25:735-741.
    • (2004) Placenta , vol.25 , pp. 735-741
    • Viero, S.1    Chaddha, V.2    Alkazaleh, F.3    Simchen, M.4    Malik, A.5    Kelly, E.6    Windrim, R.7    Kingdom, J.8
  • 5
    • 45649083688 scopus 로고    scopus 로고
    • Decreased placental X-linked inhibitor of apoptosis protein in an ovine model of intrauterine growth restriction
    • Arroyo JA, Anthony RV, Galan HL: Decreased placental X-linked inhibitor of apoptosis protein in an ovine model of intrauterine growth restriction. Am J Obstet Gynecol 2008; 199:80-88.
    • (2008) Am J Obstet Gynecol , vol.199 , pp. 80-88
    • Arroyo, J.1    Anthony, R.2    Galan, H.3
  • 6
    • 33747875000 scopus 로고    scopus 로고
    • Differential expression of placental and vascular endothelial nitric oxide synthase in an ovine model of fetal growth restriction
    • Arroyo JA, Anthony RV, Parker TA, Galan HL: Differential expression of placental and vascular endothelial nitric oxide synthase in an ovine model of fetal growth restriction. Am J Obstet Gynecol 2006; 195:771-777.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 771-777
    • Arroyo, J.1    Anthony, R.2    Parker, T.3    Galan, H.4
  • 8
    • 0035018272 scopus 로고    scopus 로고
    • Cotyledon and binucleate cell nitric oxide synthase expression in an ovine model of fetal growth restriction
    • Galan HL, Regnault TR, Le Cras TD, Tyson RW, Anthony RV, Wilkening RB, Abman SH: Cotyledon and binucleate cell nitric oxide synthase expression in an ovine model of fetal growth restriction. J Appl Physiol 2001; 90:2420-2426.
    • (2001) J Appl Physiol , vol.90 , pp. 2420-2426
    • Galan, H.1    Regnault, T.2    Le Cras, T.3    Tyson, R.4    Anthony, R.5    Wilkening, R.6    Abman, S.7
  • 9
    • 33644808501 scopus 로고    scopus 로고
    • Placental expression of angiopoietin-1, angiopoietin-2 and tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction
    • Hagen AS, Orbus RJ, Wilkening RB, Regnault TR, Anthony RV: Placental expression of angiopoietin-1, angiopoietin-2 and tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction. Pediatr Res 2005; 58:1228-1232.
    • (2005) Pediatr Res , vol.58 , pp. 1228-1232
    • Hagen, A.1    Orbus, R.2    Wilkening, R.3    Regnault, T.4    Anthony, R.5
  • 10
    • 0031767595 scopus 로고    scopus 로고
    • Expression of endothelial (type III) nitric oxide synthase in cytotrophoblastic cell lines: regulation by hypoxia and inflammatory cytokines
    • Kiss H, Schneeberger C, Tschugguel W, Lass H, Huber JC, Husslein P, Knöfler M: Expression of endothelial (type III) nitric oxide synthase in cytotrophoblastic cell lines: regulation by hypoxia and inflammatory cytokines. Placenta 1998; 19:603-611.
    • (1998) Placenta , vol.19 , pp. 603-611
    • Kiss, H.1    Schneeberger, C.2    Tschugguel, W.3    Lass, H.4    Huber, J.5    Husslein, P.6    Knöfler, M.7
  • 11
    • 0025971084 scopus 로고
    • The action of nitric oxide in the perfused human fetal-placental circulation
    • Myatt L, Brewer A, Brockman DE: The action of nitric oxide in the perfused human fetal-placental circulation. Am J Obstet Gynecol 1991; 164:687-692.
    • (1991) Am J Obstet Gynecol , vol.164 , pp. 687-692
    • Myatt, L.1    Brewer, A.2    Brockman, D.3
  • 12
    • 28344446814 scopus 로고    scopus 로고
    • Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies
    • Schiessl B, Mylonas I, Hantschmann P, Kuhn C, Schulze S, Kunze S, Friese K, Jeschke U: Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies. J Histochem Cytochem 2005; 53:1441-1449.
    • (2005) J Histochem Cytochem , vol.53 , pp. 1441-1449
    • Schiessl, B.1    Mylonas, I.2    Hantschmann, P.3    Kuhn, C.4    Schulze, S.5    Kunze, S.6    Friese, K.7    Jeschke, U.8
  • 13
    • 0031447022 scopus 로고    scopus 로고
    • Increased placental apoptosis in intrauterine growth restriction
    • Smith SC, Baker PN, Symonds EM: Increased placental apoptosis in intrauterine growth restriction. Am J Obstet Gynecol 1997; 177:1395-1401.
    • (1997) Am J Obstet Gynecol , vol.177 , pp. 1395-1401
    • Smith, S.1    Baker, P.2    Symonds, E.3
  • 15
    • 0025883342 scopus 로고
    • Nitric oxide: physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA: Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43:109-142.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.2    Higgs, E.3
  • 16
    • 0030857586 scopus 로고    scopus 로고
    • Comparative localization of endothelial and inducible nitric oxide synthase isoforms in haemochorial and epitheliochorial placentae
    • Zarlingo TJ, Eis AL, Brockman DE, Kossenjans W, Myatt L: Comparative localization of endothelial and inducible nitric oxide synthase isoforms in haemochorial and epitheliochorial placentae. Placenta 1997; 18:511-520.
    • (1997) Placenta , vol.18 , pp. 511-520
    • Zarlingo, T.1    Eis, A.2    Brockman, D.3    Kossenjans, W.4    Myatt, L.5
  • 18
    • 0037216768 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase
    • Fleming I, Busse R: Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 2003; 284:R1-R12.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284
    • Fleming, I.1    Busse, R.2
  • 19
    • 0035192750 scopus 로고    scopus 로고
    • Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough?
    • Fulton D, Gratton JP, Sessa WC: Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 2001; 299:818-824.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 818-824
    • Fulton, D.1    Gratton, J.2    Sessa, W.3
  • 20
    • 0032930417 scopus 로고    scopus 로고
    • Mammalian nitric oxide synthases
    • Stuehr DJ: Mammalian nitric oxide synthases. Biochim Biophys Acta 1999; 1411:217-230.
    • (1999) Biochim Biophys Acta , vol.1411 , pp. 217-230
    • Stuehr, D.1
  • 21
    • 0034151638 scopus 로고    scopus 로고
    • Trophoblast apoptosis and placental development - a workshop report
    • Huppertz B, Hunt JS: Trophoblast apoptosis and placental development - a workshop report. Placenta 2000; 21(Suppl. A):S74-S76.
    • (2000) Placenta , vol.21 , Issue.SUPPL. A
    • Huppertz, B.1    Hunt, J.2
  • 22
    • 0033954382 scopus 로고    scopus 로고
    • To be, or not to be, that is the question. Apoptosis in human trophoblast
    • Levy R, Nelson DM: To be, or not to be, that is the question. Apoptosis in human trophoblast. Placenta 2000; 21:1-13.
    • (2000) Placenta , vol.21 , pp. 1-13
    • Levy, R.1    Nelson, D.2
  • 23
    • 0035866784 scopus 로고    scopus 로고
    • Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation
    • Chen EY, Mazure NM, Cooper JA, Giaccia AJ: Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer Res 2001; 61:2429-2433.
    • (2001) Cancer Res , vol.61 , pp. 2429-2433
    • Chen, E.1    Mazure, N.2    Cooper, J.3    Giaccia, A.4
  • 25
    • 1942539928 scopus 로고    scopus 로고
    • Deferential regulation of placenta growth factor (PlGF)-mediated signal transduction in human primary term trophoblast and endothelial cells
    • Arroyo J, Torry RJ, Torry DS: Deferential regulation of placenta growth factor (PlGF)-mediated signal transduction in human primary term trophoblast and endothelial cells. Placenta 2004; 25:379-386.
    • (2004) Placenta , vol.25 , pp. 379-386
    • Arroyo, J.1    Torry, R.2    Torry, D.3
  • 26
    • 1542609163 scopus 로고    scopus 로고
    • Hypoxia increases Hsp90 binding to eNOS via PI3K-Akt in porcine coronary artery endothelium
    • Chen JX, Meyrick B: Hypoxia increases Hsp90 binding to eNOS via PI3K-Akt in porcine coronary artery endothelium. Lab Invest 2004; 84:182-190.
    • (2004) Lab Invest , vol.84 , pp. 182-190
    • Chen, J.1    Meyrick, B.2
  • 27
    • 0034128782 scopus 로고    scopus 로고
    • Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor
    • Levy R, Smith SD, Chandler K, Sadovsky Y, Nelson DM: Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor. Am J Physiol Cell Physiol 2000; 278:C982-C988.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Levy, R.1    Smith, S.2    Chandler, K.3    Sadovsky, Y.4    Nelson, D.5
  • 29
    • 34247481451 scopus 로고    scopus 로고
    • Suppression of hypoxic cell death by APIP-induced sustained activation of AKT and ERK1/2
    • Cho DH, Lee HJ, Kim HJ, Hong SH, Pyo JO, Cho C, Jung YK: Suppression of hypoxic cell death by APIP-induced sustained activation of AKT and ERK1/2. Oncogene 2007; 26:2809-2814.
    • (2007) Oncogene , vol.26 , pp. 2809-2814
    • Cho, D.1    Lee, H.2    Kim, H.3    Hong, S.4    Pyo, J.5    Cho, C.6    Jung, Y.7
  • 30
    • 0036997701 scopus 로고    scopus 로고
    • Modulation of trophoblast cell death by oxygen and EGF
    • Perkins J, St John J, Ahmed A: Modulation of trophoblast cell death by oxygen and EGF. Mol Med 2002; 8:847-856.
    • (2002) Mol Med , vol.8 , pp. 847-856
    • Perkins, J.1    St John, J.2    Ahmed, A.3
  • 31
    • 0141614928 scopus 로고    scopus 로고
    • Effect of oxygen levels in villous trophoblast apoptosis
    • Kilani RT, Mackova M, Davidge ST, Guilbert LJ: Effect of oxygen levels in villous trophoblast apoptosis. Placenta 2003; 24:826-834.
    • (2003) Placenta , vol.24 , pp. 826-834
    • Kilani, R.1    Mackova, M.2    Davidge, S.3    Guilbert, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.