Safety and pharmacokinetics of etravirine in pregnant HIV-1-infected women

HIV Medicine

Volumn 12, Issue 4, 2011, Pages 257-258

  Izurieta, P ^a   Kakuda, T N ^b   Feys, C ^c   Witek, J ^b  

^a GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^b Tibotec Inc   (United States)

^c TIBOTEC BVBA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DARUNAVIR PLUS RITONAVIR; ENFUVIRTIDE; ETRAVIRINE;

DRUG BLOOD LEVEL; DRUG SAFETY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LETTER; NONHUMAN; PREGNANCY OUTCOME; PREGNANT WOMAN; PRIORITY JOURNAL; THIRD TRIMESTER PREGNANCY; VERTICAL TRANSMISSION; VIRUS LOAD;

ADULT; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PYRIDAZINES; TREATMENT OUTCOME;

EID: 79952288406     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2010.00874.x     Document Type: Letter

References (5)

1. Kakuda TN, Wade JR, Snoeck E et al. Pharmacokinetics and pharmacodynamics of the non-nucleoside reverse transcriptase inhibitor etravirine in treatment-experienced HIV-1-infected patients. Clin Pharmacol Ther. In press.
2. Raoof A, Lachau-Durand S, Verbeeck J, Bailey G, Martens M. Etravirine has no effect on fetal development in rats and rabbits. 17th International AIDS Conference. Mexico City, Mexico, August 2008 [Abstract TUPE0013].
3. Kakuda TN, Schöller-Gyüre M, Peeters M et al. Pharmacokinetics of etravirine are not affected by sex, age, race, treatment duration or use of enfuvirtide in HIV-1-infected subjects. 17th International AIDS Conference. Mexico City, Mexico, August 2008 [Abstract TUPE0082].
4. Furco A, Gosrani B, Nicholas S et al. Successful use of darunavir, etravirine, enfuvirtide and tenofovir/emtricitabine in pregnant woman with multiclass HIV resistance. AIDS 2009; 23: 434-435.
5. Antiretroviral Pregnancy Registry Steering Committee. Antiretroviral Pregnancy Registry International Interim Report for 1 January 1989 through 31 July 2009. Wilmington, NC: Registry Coordinating Center, 2009. Available at (accessed 19 May 2010).