Appropriate dose for degradation of levofloxacin lactate: Gamma radiolysis and assessment of degradation product activity and cytotoxicity

Environmental Engineering Science

Volumn 28, Issue 3, 2011, Pages 183-189

  Cao, Dongmei ^a   Zhang, Xiaohong ^a   Zhao, Suying ^b   Guan, Yu ^a   Zhang, Haiqian ^a,c  

^a NANJING UNIVERSITY OF AERONAUTICS AND ASTRONAUTICS   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c Southeast University   (China)

Author keywords

activity; cytotoxicity; gamma irradiation; LC MS; levofloxacin lactate; radiolysis

Indexed keywords

ACTIVE PARTS; ACTIVITY; ANTIBIOTIC RESIDUES; ANTIMICROBIAL RESISTANCES; AQUATIC SYSTEM; DEGRADATION PRODUCTS; ENVIRONMENTAL EFFECTS; G-VALUES; GAMMA IRRADIATION; GAMMA RADIOLYSIS; INHIBITORY CONCENTRATION; LC-MS; LEVOFLOXACIN; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MINIMAL INHIBITORY CONCENTRATION; PARENT STRUCTURE; PROLIFERATION RATE; QUINOLONES; RADIATION DOSE; RADIOLYSIS PRODUCTS; RESISTANT BACTERIA;

ANTIBIOTICS; CYTOTOXICITY; ESCHERICHIA COLI; GAMMA RAYS; IRRADIATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PETROLEUM TAR; RADIATION CHEMISTRY; RADIOLYSIS; RATING;

DEGRADATION;

ANTIBIOTIC AGENT; COBALT 60; LACTIC ACID; LEVOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DEGRADATION; GAMMA IRRADIATION; LIQUID CHROMATOGRAPHY; LYMPHOCYTE CULTURE; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; RADIATION DOSE; RADIOLYSIS; ULTRAVIOLET SPECTROSCOPY; WATER CONTAMINATION;

ESCHERICHIA COLI;

EID: 79952287409     PISSN: 10928758     EISSN: None     Source Type: Journal    
DOI: 10.1089/ees.2010.0119     Document Type: Article

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