Radiosynthesis and biological evaluation of 99mTcN-sitafloxacin dithiocarbamate as a potential radiotracer for Staphylococcus aureus infection

Journal of Radioanalytical and Nuclear Chemistry

Volumn 287, Issue 3, 2011, Pages 827-832

  Shah, Syed Qaiser ^c   Khan, Aakif Ullah ^a   Khan, Muhammad Rafiullah ^b  

^a PAKISTAN ATOMIC ENERGY COMMISSION   (Pakistan)

^b UNIVERSITY OF PESHAWAR   (Pakistan)

^c NONE

Author keywords

99mTc N 2+ core; Infection; Sitafloxacin dithiocarbamate; Staphylococcus aureus

Indexed keywords

PERTECHNETIC ACID TC 99M; SITAFLOXACIN; SITAFLOXACIN DITHIOCARBAMATE; TECHNETIUM 99M; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; IN VITRO STUDY; ISOTOPE LABELING; MALE; MUSCLE; NONHUMAN; RABBIT; RADIOASSAY; RADIOCHEMISTRY; RAT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SUBSTITUTION REACTION;

EID: 79952281733     PISSN: 02365731     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10967-010-0833-9     Document Type: Article

References (22)

1. W Bruggen CP Bleeker-Rovers OC Boerman M Gotthardt WJG Oyen 2010 PET and SPECT in osteomyelitis and prosthetic bone and joint infections: a systematic review Semin Nucl Med 40 3 10.1053/j.semnuclmed.2009.08.005
2. S Basu T Chryssikos S Moghadam-Kia H Zhuang DA Torigian A Alvai 2009 Positron emission tomography as a diagnostic tool in infection: present role and future possibilities Semin Nucl Med 39 36 10.1053/j.semnuclmed.2008.08.004
3. 99mTc]-technetium stannous colloid is complement receptor 3-mediated and increases the neutrophil priming response to lipopolysaccharide Nucl Med Biol 33 433 10.1016/j.nucmedbio.2005.12.014 1:CAS:528:DC%2BD28Xjs1GktL0%3D
4. S Lahiri S Sarkar 2007 Studies on 66, 67 Ga- and 199Tl-poly(N- vinylpyrrolidone) complexes Appl Radiat Isot 65 309 10.1016/j.apradiso.2006.10. 003 1:CAS:528:DC%2BD2sXksFam (Pubitemid 46001742)
5. 99mTc complex: a potential new brain imaging agent J Radioanal Nucl Chem 273 15 10.1007/s10967-007-0703-2
6. 2 and its biodistribution in mice J Radioanal Nucl Chem 249 573
7. 99mTc-Sitafloxacin kit: a novel infection imaging agent J Radioanal Nucl Chem 284 189 10.1007/s10967-010-0470-3 1:CAS:528: DC%2BC3cXjtlGgt78%3D
8. 99mTc- nitrifuratonin a novel radiotracer for in vivo imaging of Escherichia coli infection. J Radioanal Nucl Chem
9. 99mTc-rifampicin: a novel radiotracer for in vivo infection imaging Appl Radiat Isot 68 2255 10.1016/j.apradiso.2010.05.014 1:CAS:528: DC%2BC3cXhtFCgsbrK
10. 99mTc-Novobiocin: a novel radiotracer for infection imaging. Radiochimica acta
11. 99mTc-Teicoplanin complex in artificially infected animal models. J Labeled Comp Radiopharm
12. 99mTc-labeled ciprofloxacin in mice Chin Med J 122 1907
13. 99mTc-ciprofloxacin by different methods and its biodistribution Appl Radiat Isot 57 193 10.1016/S0969-8043(02)00107-0 1:CAS:528:DC%2BD38XksVCqsbs%3D (Pubitemid 34607656)
14. 99mTcN complex of ciprofloxacin dithiocarbamate as a potential agent for infection imaging Bioorg Med Chem Lett 18 51
15. 99mTc-cefoperazone complex, a novel agent for detecting sites of infection J Radioanal Nucl Chem 272 167 10.1007/s10967-006-6754-y 1:CAS:528:DC%2BD2sXisV2iu7g%3D (Pubitemid 46354750)
16. 99mTc-olfloxacin complex J Radioanal Nucl Chem 272 95 10.1007/s10967-006-6786-3 1:CAS:528:DC%2BD2sXisV2hsro%3D (Pubitemid 46354758)
17. 99mTc-pefloxacin:A new targeting agent for infectious foci J Radioanal Nucl Chem 266 131 10.1007/s10967-005-0881-8
18. 99mTc-Kanamycin J Radioanal Nucl Chem 267 561 10.1007/s10967-006-0087-8 1:CAS:528:DC%2BD28Xhs12gtrs%3D (Pubitemid 43288688)
19. 99mTc-sparafloxacin complex, a novel agent for detecting sites of infection J Labelled Comp Radiopharm 52 415 10.1002/jlcr.1619 1:CAS:528:DC%2BD1MXhtFGku7%2FL
20. 99mTc-moxifloxacin, a potential infection specific imaging agent. Appl Radiat Isot. 68: 314
21. MM Welling A Paulusma-Annema HS Batler EKJ Pauwels PH Nibbering 2000 Technetium-99m labelled antimicrobial peptides discriminate between bacterial infections and sterile inflammations Eur J Nucl Med 27 292 10.1007/s002590050036 1:CAS:528:DC%2BD3cXhsVWns7o%3D
22. J Baldas J Bonnyman PM Poer GA Williams MF Mackay 1981 Synthesis And Structure of bis(diethyldithiocarbamato)nitridotechnetium(V)-a technetium-nitrogen triple bond J Chem Soc Dalton Trans 9 1798 10.1039/dt9810001798