Age and gender differences in symptom intensity and symptom clusters among patients with metastatic cancer

Supportive Care in Cancer

Volumn 19, Issue 3, 2011, Pages 417-423

  Cheung, Winson Y ^a   Le, Lisa W ^d   Gagliese, Lucia ^b,e   Zimmermann, Camilla ^c,e  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b YORK UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Advanced cancer; Age; Gender; Palliative care; Symptom clusters

Indexed keywords

ADULT; ADVANCED CANCER; AGE; AGED; ANXIETY; APPETITE; ARTICLE; BREAST CANCER; CANCER LOCALIZATION; CANCER PAIN; CANCER PATIENT; CONTROLLED STUDY; DEPRESSION; DIGESTIVE SYSTEM CANCER; DISEASE SEVERITY; DROWSINESS; DYSPNEA; EDMONTON SYMPTOM ASSESSMENT SYSTEM; FATIGUE; FEMALE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; METASTASIS; NAUSEA; PATIENT ASSESSMENT; PRIORITY JOURNAL; SCORING SYSTEM; SEX DIFFERENCE; SYMPTOMATOLOGY;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANXIETY; APPETITE; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM METASTASIS; NEOPLASMS; PAIN; PALLIATIVE CARE; PRINCIPAL COMPONENT ANALYSIS; SEX FACTORS; YOUNG ADULT;

EID: 79952243310     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-010-0865-2     Document Type: Article

References (56)

1. AZ Doorenbos CW Given B Given N Verbitsky 2006 Symptom experience in the last year of life among individuals with cancer J Pain Symptom Manage 32 403 412 17085266 10.1016/j.jpainsymman.2006.05.023 (Pubitemid 44755109)
2. SC Teunissen W Wesker C Kruitwagen HC de Haes EE Voest A de Graeff 2007 Symptom prevalence in patients with incurable cancer: a systematic review J Pain Symptom Manage 34 94 104 17509812 10.1016/j.jpainsymman.2006.10.015 (Pubitemid 46970881)
3. EP McCarthy RS Phillips Z Zhong RE Drews J Lynn 2000 Dying with cancer: patients' function, symptoms, and care preferences as death approaches J Am Geriatr Soc 48 5 Suppl S110 S121 10809464 1:STN:280:DC%2BD3c3mslClsw%3D%3D
4. WY Cheung N Barmala S Zarinehbaf G Rodin LW Le C Zimmermann 2009 The association of physical and psychological symptom burden with time to death among palliative cancer outpatients J Pain Symptom Manage 37 297 304 18694634 10.1016/j.jpainsymman.2008.03.008
5. AF Husain K Stewart R Arsenault R Moineddin V Cellarius SL Librach, et al. 2007 Women experience higher levels of fatigue than men at the end of life: a longitudinal home palliative care study J Pain Symptom Manage 33 389 397 17397700 10.1016/j.jpainsymman.2006.09.019 (Pubitemid 46505074)
6. MS Jordhoy P Fayers JH Loge T Saltnes M Ahlner-Elmqvist S Kaasa 2001 Quality of life in advanced cancer patients: the impact of sociodemographic and medical characteristics Br J Cancer 85 1478 1485 11720432 10.1054/bjoc.2001.2116 1:STN:280:DC%2BD3MnnsVyguw%3D%3D (Pubitemid 34001577)
7. D Walsh S Donnelly L Rybicki 2000 The symptoms of advanced cancer: relationship to age, gender, and performance status in 1,000 patients Support Care Cancer 8 175 179 10789956 10.1007/s005200050281 1:STN:280: DC%2BD3c3kvVyiug%3D%3D (Pubitemid 30183032)
8. Zimmermann C, Burman D, Follwell M, Wakimoto K, Seccareccia D, Bryson J, Le L, Rodin G. Predictors of symptom severity and response in patients with metastatic cancer. Am J Hosp Palliat Med. 2010 Oct 16. [Epub ahead of print] in press
9. WY Cheung LW Le C Zimmermann 2009 Symptom clusters in patients with advanced cancers Support Care Cancer 17 9 1223 1230 19184126 10.1007/s00520-009-0577-7
10. E Bruera N Kuehn MJ Miller P Selmser K Macmillan 1991 The Edmonton symptom assessment system (ESAS): a simple method for the assessment of palliative care patients J Palliat Care 7 6 9 1714502 1:STN:280: DyaK3Mzjt1OqtA%3D%3D
11. G Fan L Filipczak E Chow 2007 Symptom clusters in cancer patients: a review of the literature Curr Oncol 14 173 179 17938700 10.3747/co.2007.145 1:STN:280:DC%2BD2snhsVGisA%3D%3D
12. HJ Kim DB McGuire L Tulman AM Barsevick 2005 Symptom clusters: concept analysis and clinical implications for cancer nursing Cancer Nurs 28 270 284 16046888 (Pubitemid 41098333)
13. MJ Dodd C Miaskowski SM Paul 2001 Symptom clusters and their effect on the functional status of patients with cancer Oncol Nurs Forum 28 465 470 11338755 1:STN:280:DC%2BD3MrgsV2gtw%3D%3D
14. C Zimmermann D Seccareccia A Clarke D Warr G Rodin 2006 Bringing palliative care to a Canadian cancer center: the palliative care program at Princess Margaret Hospital Support Care Cancer 14 982 987 16802127 10.1007/s00520-006-0093-y (Pubitemid 44451303)
15. VT Chang SS Hwang M Feuerman 2000 Validation of the Edmonton symptom assessment scale Cancer 88 2164 2171 10813730 10.1002/(SICI)1097-0142(20000501) 88:9<2164::AID-CNCR24>3.0.CO;2-5 1:STN:280:DC%2BD3c3ntlGjsw%3D%3D (Pubitemid 30233220)
16. D Dudgeon V Vaitonis H Seow, et al. 2007 Ontario, Canada: using networks to integrate palliative care province-wide J Pain Symptom Manage 33 640 644 17482061 10.1016/j.jpainsymman.2007.02.001 (Pubitemid 46680385)
17. K Webster D Cella K Yost 2003 The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: properties, applications, and interpretation Health Qual Life Outcomes 1 79 14678568 10.1186/1477-7525-1-79 (Pubitemid 39111917)
18. Fayers PM, Aaronson NK, Bjordal K et al (2001) European Organisation for Research and Treatment of Cancer QLQ-C30 Scoring Manual, ed 3rd edn. EORTC Quality of Life Group, Brussels
19. C Miaskowski BE Aouizerat M Dodd B Cooper 2007 Conceptual issues in symptom clusters research and their implications for quality-of-life assessment in patients with cancer J Natl Cancer Inst Monogr 37 39 46 17951230 10.1093/jncimonographs/lgm003
20. AM Barsevick K Whitmer LM Nail SL Beck WN Dudley 2006 Symptom cluster research: conceptual design, measurement, and analysis issues J Pain Symptom Manage 31 85 95 16442485 10.1016/j.jpainsymman.2005.05.015 (Pubitemid 43143301)
21. L Gagliese R Melzack 2003 Age-related differences in the qualities but not the intensity of chronic pain Pain 104 597 608 12927632 10.1016/S0304- 3959(03)00117-9 (Pubitemid 37289059)
22. L Gagliese J Katz 2003 Age differences in post-operative pain are scale dependent: a comparison of measures of pain intensity and quality in younger and older surgical patients Pain 103 11 20 12749954 10.1016/S0304-3959(02)00327-5 (Pubitemid 36579080)
23. Gagliese L, Jovellanos M, Zimmermann C, Shobbrook C, Warr D, Rodin G (2009) Age-related patterns in adaptation to cancer pain. Pain Med 10:1050-1061
24. J Ringash B O'Sullivan A Bezjak, et al. 2007 Interpreting clinically significant changes in patient reported outcomes Cancer 110 196 202 17546575 10.1002/cncr.22799 (Pubitemid 46986433)
25. D Osoba G Rodrigues J Myles, et al. 1998 Interpreting the significance of changes in health-related quality-of-life socres J Clin Oncol 16 139 144 9440735 1:STN:280:DyaK1c7gtFKrtw%3D%3D (Pubitemid 28041591)
26. B Barrett D Brown M Mundt, et al. 2005 Sufficiently important difference: expanding the framework of clinical significance Med Decis Making 25 250 261 15951453 10.1177/0272989X05276863 (Pubitemid 40696275)
27. RP Riechelmann C Zimmermann SN Chin L Wang A O'Carroll S Zarinehbaf, et al. 2008 Potential drug interactions in cancer patients receiving supportive care exclusively J Pain Symptom Manage 35 535 543 18243638 10.1016/j. jpainsymman.2007.06.009
28. RP Riechelmann MK Krzyzanowska A O'Carroll C Zimmermann 2007 Symptom and medication profiles among cancer patients attending a palliative care clinic Support Care Cancer 15 1407 1412 17429699 10.1007/s00520-007-0253-8 (Pubitemid 350077220)
29. DB Bekelman JS Rumsfeld EP Havranek TE Yamashita E Hutt SH Gottlieb, et al. 2009 Symptom burden, depression, and spiritual well-being: a comparison of heart failure and advanced cancer patients J Gen Intern Med 24 592 598 19288160 10.1007/s11606-009-0931-y
30. JM Habraken G ter Riet JM Gore MA Greenstone EJ Weersink PJ Bindels, et al. 2009 Health-related quality of life in end-stage COPD and lung cancer patients J Pain Symptom Manage 37 973 981 19394792 10.1016/j.jpainsymman.2008. 07.010
31. Baumann R, Putz C, Rohrig B, Hoffken K, Wedding U (2009) Health-related quality of life in elderly cancer patients, elderly non-cancer patients and an elderly general population. Eur J Cancer Care (Engl) 18:457-465
32. CE Schmidt B Bestmann T Kuchler WE Longo B Kremer 2005 Impact of age on quality of life in patients with rectal cancer World J Surg 29 190 197 15654662 10.1007/s00268-004-7556-4 (Pubitemid 40576468)
33. JF Cleary PP Carbone 1997 Palliative medicine in the elderly Cancer 80 1335 1347 9317188 10.1002/(SICI)1097-0142(19971001)80:7<1335::AID- CNCR21>3.0.CO;2-7 1:STN:280:DyaK2svmtFGjtQ%3D%3D (Pubitemid 27407238)
34. B Holzner G Kemmler D Cella C De Paoli V Meraner M Kopp, et al. 2004 Normative data for functional assessment of cancer therapy-general scale and its use for the interpretation of quality of life scores in cancer survivors Acta Oncol 43 153 160 15163163 10.1080/02841860310023453 (Pubitemid 38478901)
35. MJ Hjermstad PM Fayers K Bjordal S Kassa 1998 Health-related quality of life in the general Norwegian population assessed by the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionniare: the QLQ=C30(+3) J Clin Oncol 16 1188 1196 9508207 1:STN:280:DyaK1c7mslKgsA%3D%3D (Pubitemid 28108757)
36. LE Carlson M Angen J Cullum E Goodey J Koopmans L Lamont, et al. 2004 High levels of untreated distress and fatigue in cancer patients Br J Cancer 90 2297 2304 15162149 1:STN:280:DC%2BD2c3os1ertQ%3D%3D (Pubitemid 38961891)
37. V Strong R Waters C Hibberd R Rush A Cargill D Storey, et al. 2007 Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study Br J Cancer 96 868 874 17311020 10.1038/sj.bjc.6603626 1:STN:280: DC%2BD2s7ntFSktg%3D%3D (Pubitemid 46452277)
38. S Pascoe S Edelman A Kidman 2000 Prevalence of psychological distress and use of support services by cancer patients at Sydney hospitals Aust N Z J Psychiatry 34 785 791 11037364 1:STN:280:DC%2BD3cvos12itA%3D%3D
39. N Aass SD Fossa AA Dahl TJ Moe 1997 Prevalence of anxiety and depression in cancer patients seen at the Norwegian Radium Hospital Eur J Cancer 33 1597 1604 9389921 10.1016/S0959-8049(97)00054-3 1:STN:280:DyaK1c%2FltFelsg%3D%3D (Pubitemid 28123481)
40. M Hamadani L Chaudhary FT Awan, et al. 2007 Management of platinum-based chemotherapy-induced acute nausea and vomiting: is there a superior serotonin receptor antagonist? J Oncol Pharm Pract 13 69 75 17873106 10.1177/ 1078155207078137 1:CAS:528:DC%2BD2sXht1amt7bL (Pubitemid 47399302)
41. V Shih HS Wan A Chan 2009 Clinical predictors of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adjuvant doxorubicin and cyclophosphamide Ann Pharmacother 43 444 452 19193584 10.1345/aph.1L437
42. CF Pollera D Giannarelli 1989 Prognostic factors influencing cisplatin-induced emesis. Definition and validation of a predictive logistic model Cancer 64 1117 1122 2667749 10.1002/1097-0142(19890901)64:5<1117::AID- CNCR2820640525>3.0.CO;2-R 1:STN:280:DyaL1Mzjs1Kguw%3D%3D (Pubitemid 19208867)
43. CC Liaw CH Wang HK Chang CT Liau KY Yeh JS Huang, et al. 2001 Gender discrepancy observed between chemotherapy-induced emesis and hiccups Support Care Cancer 9 435 441 11585270 10.1007/s005200000231 1:STN:280: DC%2BD3Mrjslymug%3D%3D (Pubitemid 32843630)
44. CC Liaw HK Chang CT Liau JS Huang YC Lin JS Chen 2003 Reduced maintenance of complete protection from emesis for women during chemotherapy cycles Am J Clin Oncol 26 12 15 12576917 10.1097/00000421-200302000-00003 1:CAS:528:DC%2BD3sXnsFCksrY%3D (Pubitemid 36205890)
45. M Follwell D Burman LW Le K Wakimoto D Seccareccia J Bryson, et al. 2009 Phase II study of an outpatient palliative care intervention in patients with metastatic cancer J Clin Oncol 27 206 213 19064979 10.1200/JCO.2008.17.7568
46. McCaughan E, Prue G, Parahoo K (2009) A systematic review of quantitative studies reporting selected patient experienced outcomes with a specific focus on gender differences in people with colorectal cancer. Eur J Oncol Nurs 13:376-385
47. E Chow G Fan S Hadi J Wong A Kirou-Mauro L Filipczak 2008 Symptom clusters in elderly patients with lung cancer Clin Oncol (R Coll Radiol) 20 76 82 1:STN:280:DC%2BD1c%2FltFWquw%3D%3D
48. E Chow G Fan S Hadi L Filipczak 2007 Symptom clusters in cancer patients with bone metastases Support Care Cancer 15 1035 1043 17394024 10.1007/s00520-007-0241-z (Pubitemid 47340973)
49. ML Chen HC Tseng 2006 Symptom clusters in cancer patients Support Care Cancer 14 825 830 16491377 10.1007/s00520-006-0019-8 (Pubitemid 44060995)
50. D Walsh L Rybicki 2006 Symptom clustering in advanced cancer Support Care Cancer 14 831 836 16482450 10.1007/s00520-005-0899-z (Pubitemid 44060996)
51. SH Ridner 2005 Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema Support Care Cancer 13 904 911 15812652 10.1007/s00520-005-0810-y (Pubitemid 41502250)
52. CM Bender FS Ergyn MQ Rosenzweig SM Cohen SM Sereika 2005 Symptom clusters in breast cancer across 3 phases of disease Cancer Nurs 28 219 225 15915067 10.1097/00002820-200505000-00011 (Pubitemid 40734541)
53. AG Gifts A Jablonski M Stommel CW Given 2004 Symptom clusters in elderly patients with lung cancer Oncol Nurs Forum 31 202 212
54. RB Fillingim TJ Ness TL Glover CM Campbell BA Hastie DD Price, et al. 2005 Morphine responses and experimental pain: sex differences in side effects and cardiovascular responses but not analgesia J Pain 6 116 124 15694878 10.1016/j.jpain.2004.11.005 1:CAS:528:DC%2BD2MXhtVOmtrw%3D (Pubitemid 40203048)
55. PE Bijur D Esses A Birnbaum AK Chang C Schechter EJ Gallagher 2008 Response to morphine in male and female patients: analgesia and adverse events Clin J Pain 24 192 198 18287823 10.1097/AJP.0b013e31815d3619 (Pubitemid 351640915)
56. AJ Barsky HM Peekna JF Borus 2001 Somatic symptom reporting in women and men J Gen Intern Med 16 266 275 11318929 10.1046/j.1525-1497.2001.016004266.x 1:STN:280:DC%2BD3MvgvF2nuw%3D%3D (Pubitemid 32397675)