Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay

Journal of Biomedicine and Biotechnology

Volumn 2011, Issue , 2011, Pages

  Martinez, Elisabeth D ^a   Best, Anne M ^a   Chang, Jianjun ^a   Dull, Angie B ^b   Beutler, John A ^c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b SAIC FREDERICK INC   (United States)

^c National Cancer Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; APICIDIN; BUTYRIC ACID; DACTINOMYCIN; DEPSIPEPTIDE; GREEN FLUORESCENT PROTEIN; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; NSC 150117; NSC 159631; NSC 22225; NSC 693322; ROMIDEPSIN; SECALONIC ACID D; TRICHOSTATIN A; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

ARTICLE; AUTOMATION; CANCER CELL; CELL ASSAY; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE REGULATION; CELL VIABILITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; ENZYME INHIBITION; EPIGENETICS; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LOCUS DEREPRESSION ASSAY; LUNG CANCER; MELANOMA; STRUCTURE ANALYSIS; ANIMAL; BIOASSAY; DRUG EFFECT; DRUG SCREENING; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; METABOLISM; METHODOLOGY; MOLECULAR LIBRARY; MOUSE; NATIONAL HEALTH ORGANIZATION; NEOPLASM; PATHOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE; UNITED STATES;

MAMMALIA;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL ASSAY; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; EPIGENESIS, GENETIC; GREEN FLUORESCENT PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; NATIONAL CANCER INSTITUTE (U.S.); NEOPLASMS; SMALL MOLECULE LIBRARIES; TRANSCRIPTION, GENETIC; UNITED STATES;

EID: 79952234999     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2011/868095     Document Type: Article

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