Spuriously high free thyroxine values in familial dysalbuminemic hyperthyroxinemia

Clinical Chemistry

Volumn 57, Issue 3, 2011, Pages 524-525

  Ross, H Alec ^a   De Rijke, Yolanda B ^b   Sweep, Fred C G J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

THYROXINE;

BLOOD SAMPLING; EUTHYROIDISM; FAMILIAL DYSALBUMINEMIC HYPERTHYROXINEMIA; HUMAN; LETTER; MEASUREMENT; THYROXINE BLOOD LEVEL;

BIOLOGICAL ASSAY; BUFFERS; CHLORIDES; HUMANS; HYPERTHYROXINEMIA, FAMILIAL DYSALBUMINEMIC; REAGENT KITS, DIAGNOSTIC; REPRODUCIBILITY OF RESULTS; SERUM ALBUMIN; THYROXINE; THYROXINE-BINDING PROTEINS;

EID: 79952230670     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2010.158170     Document Type: Letter

References (4)

1. Cartwright D, O'Shea P, Rajanayagam O, Agostini M, Barker P, Moran C, et al. Familial dysalbuminemic hyperthyroxinemia; a persistent diagnostic challenge. Clin Chem 2009;55:1044-6.
2. Spaulding SW, Gregerman RI. Free thyroxin by equilibrium dialysis: effect of dilution, specific ions and inhibitors of binding. J Clin Endocrinol Metab 1972;34:974-82.
3. Nelson JC, Tomei RT. Direct determination of free thyroxine in undiluted serum by equilibrium dialysis/ radioimmunoassay. Clin Chem 1988;34:1737-44.
4. Van Uytfanghe K, Stöckl D, Ross HA, Thien-pont LM. Use of frozen sera for FT4 standardization: investigation by equilibrium dialysis combined with isotope dilution mass spectrometry and immunoassay. Clin Chem 2006;52:1817-20. (Pubitemid 44330720)