Neutrophil-dominant experimental autoimmune uveitis in CC-chemokine receptor 2 knockout mice

Acta Ophthalmologica

Volumn 89, Issue 2, 2011, Pages

  Sonoda, Koh Hei ^a   Yoshimura, Takeru ^a   Egashira, Kensuke ^a   Charo, Israel F ^b   Ishibashi, Tatsuro ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

Autoimmunity; Chemokines monokines; Eye (ocular) immunology disease; Macrophages monocytes

Indexed keywords

CHEMOKINE RECEPTOR CCR2; FREUND ADJUVANT; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE UVEITIS; CELL INFILTRATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; GENE INACTIVATION; HISTOLOGY; MACROPHAGE; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; UVEITIS;

ANIMALS; AUTOIMMUNE DISEASES; CHEMOKINE CCL2; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE PROTEINS; FEMALE; FLOW CYTOMETRY; IMMUNOPHENOTYPING; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; RECEPTORS, CCR2; RETINITIS; RETINOL-BINDING PROTEINS; TH1 CELLS; UVEITIS, POSTERIOR;

EID: 79952230321     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2010.01953.x     Document Type: Article

References (36)

1. Abu El-Asrar AM, Struyf S, Opdenakker G, Geboes K & Van Damme J (2007): The role of chemokines and their receptors in uveitis. Int Ophthalmol 27: 321-327. Epub 2007 Mar 2013. (Pubitemid 47377477)
2. Adamus G, Manczak M & Machnicki M (2001): Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE. Invest Ophthalmol Vis Sci 42: 2894-2903. (Pubitemid 33035288)
3. Avichezer D, Silver PB, Chan CC, Wiggert B & Caspi RR (2000): Identification of a new epitope of human IRBP that induces auto-immune uveoretinitis in mice of the H-2b haplotype. Invest Ophthalmol Vis Sci 41: 127-131. (Pubitemid 30036558)
4. Boring L, Gosling J, Monteclaro FS, Lusis AJ, Tsou CL & Charo IF (1996): Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9. J Biol Chem 271: 7551-7558.
5. Boring L, Gosling J, Chensue SW, Kunkel SL, Farese RV Jr, Broxmeyer HE & Charo IF (1997): Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J Clin Invest 100: 2552-2561. (Pubitemid 27514895)
6. Boring L, Gosling J, Cleary M & Charo IF (1998): Decreased lesion formation in CCR2-?- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394: 894-897. (Pubitemid 28410911)
7. Butler TL & McMenamin PG (1996): Resident and infiltrating immune cells in the uveal tract in the early and late stages of experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 37: 2195-2210. (Pubitemid 26338768)
8. Caspi RR, Roberge FG, Chan CC, Wiggert B, Chader GJ, Rozenszajn LA, Lando Z & Nussenblatt RB (1988): A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens. J Immunol 140: 1490-1495.
9. Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ & Coughlin SR (1994): Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci U S A 91: 2752-2756. (Pubitemid 24139426)
10. Crane IJ, McKillop-Smith S, Wallace CA, Lamont GR & Forrester JV (2001): Expression of the chemokines MIP-1alpha, MCP-1, and RANTES in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 42: 1547-1552.
11. Dagkalis A, Wallace C, Xu H et al. (2009): Development of experimental autoimmune uveitis: efficient recruitment of monocytes is independent of CCR2. Invest Ophthalmol Vis Sci 50: 4288-4294.
12. Dick AD, McMenamin PG, Korner H, Scallon BJ, Ghrayeb J, Forrester JV & Sedgwick JD (1996): Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina. Eur J Immunol 26: 1018-1025.
13. Dijkstra CD, Dopp EA, Vogels IM & Van Noorden CJ (1987): Macrophages and dendritic cells in antigen-induced arthritis. An immunohistochemical study using cryostat sections of the whole knee joint of rat. Scand J Immunol 26: 513-523.
14. Fife BT, Huffnagle GB, Kuziel WA & Karpus WJ (2000): CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis. J Exp Med 192: 899-905.
15. Forrester JV (1990): Endogenous posterior uveitis. Br J Ophthalmol 74: 620-623.
16. Forrester JV (1991): Uveitis: pathogenesis. Lancet 338: 1498-1501.
17. Forrester JV, Huitinga I, Lumsden L & Dijkstra CD (1998): Marrow-derived activated macrophages are required during the effector phase of experimental autoimmune uveoretinitis in rats. Curr Eye Res 17: 426-437. (Pubitemid 28176909)
18. Foxman EF, Zhang M, Hurst SD, Muchamuel T, Shen D, Wawrousek EF, Chan CC & Gery I (2002): Inflammatory mediators in uveitis: differential induction of cytokines and chemokines in Th1- versus Th2- mediated ocular inflammation. J Immunol 168: 2483-2492. (Pubitemid 34171854)
19. Furutani Y, Nomura H, Notake M et al. (1989): Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF). Biochem Biophys Res Commun 159: 249-255. (Pubitemid 19087637)
20. Gaupp S, Pitt D, Kuziel WA, Cannella B & Raine CS (2003): Experimental autoimmune encephalomyelitis (EAE) in CCR2 (-?-) mice: susceptibility in multiple strains. Am J Pathol 162: 139-150. (Pubitemid 36041996)
21. Godiska R, Chantry D, Dietsch GN & Gray PW (1995): Chemokine expression in murine experimental allergic encephalomyelitis. J Neuroimmunol 58: 167-176.
22. Izikson L, Klein RS, Charo IF, Weiner HL & Luster AD (2000): Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med 192: 1075-1080.
23. Keino H, Takeuchi M, Kezuka T, Yamakawa N, Tsukahara R & Usui M (2003): Chemokine and chemokine receptor expression during experimental autoimmune uveoretinitis in mice. Graefes Arch Clin Exp Ophthalmol 241: 111-115. (Pubitemid 36747798)
24. Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K & Maeda N (1997): Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci U S A 94: 12053-12058. (Pubitemid 27467841)
25. Lu B, Rutledge BJ, Gu L et al. (1998): Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med 187: 601-608. (Pubitemid 28093362)
26. Nussenblatt RB, Kuwabara T, de Monasterio FM & Wacker WB (1981): S-antigen uveitis in primates. A new model for human disease. Arch Ophthalmol 99: 1090-1092.
27. Oshima T, Sonoda KH, Tsutsumi-Miyahara C et al. (2006): Analysis of corneal inflammation induced by cauterisation in CCR2 and MCP-1 knockout mice. Br J Ophthalmol 90: 218-222. (Pubitemid 43163855)
28. Pouvreau I, Zech JC, Thillaye-Goldenberg B, Naud MC, Van Rooijen N & de Kozak Y (1998): Effect of macrophage depletion by liposomes containing dichloromethylene-diphosphonate on endotoxin-induced uveitis. J Neuroimmunol 86: 171-181. (Pubitemid 28305359)
29. Rizzo LV, Silver P, Wiggert B, Hakim F, Gazzinelli RT, Chan CC & Caspi RR (1996): Establishment and characterization of a murine CD4+ T cell line and clone that induce experimental autoimmune uveoretinitis in B10.A mice. J Immunol 156:1654-1660. (Pubitemid 26065877)
30. Sakane T, Takeno M, Suzuki N & Inaba G (1999): Behcet's disease. N Engl J Med 341: 1284-1291. (Pubitemid 29489745)
31. Sonoda KH, Sasa Y, Qiao H et al. (2003): Immunoregulatory role of ocular macrophages: the macrophages produce RANTES to suppress experimental autoimmune uveitis. J Immunol 171: 2652-2659. (Pubitemid 37025579)
32. Takase H, Sugita S, Taguchi C, Imai Y & Mochizuki M (2006): Capacity of ocular infiltrating T helper type 1 cells of patients with non-infectious uveitis to produce chemokines. Br J Ophthalmol 90: 765-768. (Pubitemid 43835498)
33. Takeuchi A, Usui Y, Takeuchi M et al. (2005): CCR5-deficient mice develop experimental autoimmune uveoretinitis in the context of a deviant effector response. Invest Ophthalmol Vis Sci 46: 3753-3760. (Pubitemid 44264682)
34. Thurau SR, Chan CC, Nussenblatt RB & Caspi RR (1997): Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animals. Clin Exp Immunol 109: 370-376. (Pubitemid 27308427)
35. Verma MJ, Lloyd A, Rager H, Strieter R, Kunkel S, Taub D & Wakefield D (1997): Chemokines in acute anterior uveitis. Curr Eye Res 16: 1202-1208. (Pubitemid 27515674)
36. Zhang N, Schroppel B, Lal G et al. (2009): Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. Immunity 30: 458-469.