Effects of taspine on proliferation and apoptosis by regulating caspase-3 expression and the ratio of Bax/Bcl-2 in A431 cells

Phytotherapy Research

Volumn 25, Issue 3, 2011, Pages 357-364

  Zhang, Yanmin ^a   Jiang, Qiao ^a   Wang, Nan ^a   Dai, Bingling ^a   Chen, Yinnan ^a   He, Langchong ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

A431 cells; Apoptosis; Proliferation; Protein expression; Taspine

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALKALOID DERIVATIVE; CASPASE 3; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; PROTEIN BAX; PROTEIN BCL 2; TASPINE; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHROMATIN; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ALKALOIDS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; HUMANS; MOLECULAR STRUCTURE; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 79952216414     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3268     Document Type: Article

References (33)

1. Adams JM, Cory S. 1998. The Bcl-2 protein family: arbiters of cell survival. Science 281: 1322-1326. (Pubitemid 28406819)
2. Aikawa R, Komuro I, Yamazaki T et al. 1997. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest 100: 1813-1821. (Pubitemid 27431340)
3. Alnemri ES, Livingston DJ, Nicholson DW et al. 1996. Human ICE/CED-3 protease nomenclature. Cell 87: 171.
4. Bernecker OY, Huq F, Heist EK, Podesser BK, Hajjar RJ. 2003. Apoptosis in heart failure and the senescent heart. Cardiovasc Toxicol 3: 183-190. (Pubitemid 37296072)
5. Choi EJ, Kim GH. 2008. Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells. Phytomedicine 15: 683-690.
6. Farrow SN, Brown R. 1996. New members of the Bcl-2 family and their protein partners. Curr Opin Genet Dev 6: 45-49.
7. Han YH, Kim SH, Kim SZ, Park WH. 2008. Antimycin A as a mitochondria damage agent induces an S phase arrest of the cell cycle in HeLa cells. Life Sci 83: 346-355.
8. Hao LL, Mei QB, Zhang BL, Jia M, Li XQ, Zhang F. 2004. PC-407 inhibited proliferation and induced apoptosis in human colon cancer SW-1116 cells. Acta Pharmacol Sin 25: 1509-1514. (Pubitemid 39490898)
9. Hsu SL, Yin SC, Liu MC, Reichert U, Ho WL. 1999. Involvement of cyclin dependent kinase activities in CD 437-induced apoptosis. Exp Cell Res 252: 332-341. (Pubitemid 29530263)
10. Kameswaran TR, Ramanibai R. 2009. Indirubin-3-monooxime induced cell cycle arrest and apoptosis in Hep-2 human laryngeal carcinoma cells. Biomed Pharmacother 63: 146-154.
11. Kelly TR, Xie RL. 1998. Total synthesis of taspine. J Org Chem 63: 8045-8048. (Pubitemid 28518844)
12. Lee HZ, Leung HW, Lai MY, Wu CH. 2005. Baicalein induced cell cycle arrest and apoptosis in human lung squamous carcinoma CH27 cells. Anticancer Res 25: 959-964.
13. Lin CM, Chang H, Chen YH, Li SY, Wu IH, Chiu JH. 2006. Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1. Int Immunopharmacol 6: 1690-1698. (Pubitemid 44344541)
14. Metrailler-Ruchonnet I, Pagano A, Carnesecchi S, Ody C, Donati Y, Barazzone-Argiroffo C. 2007. Bcl-2 protects against hyperoxia-induced apoptosis through inhibition of the mitochondria-dependent pathway. Free Radic Biol Med 42: 1062-1074. (Pubitemid 46356899)
15. Mu H, Ohashi R, Yan SY et al. 2006. Adipokine resistin promotes in vitro angiogenesis of human endothelial cells. Cardiovasc Res 70: 146-157.
16. Naruse I, Ohmori T, Ao Y et al. 2002. Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) Iressa (ZD1839) in an EGFR-expressing multidrug-resistant cell line in vitro and in vivo. Int J Cancer 98: 310-315. (Pubitemid 34150818)
17. Oberhammer F, Wilson JW, Dive C et al. 1993. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12: 3679-3684. (Pubitemid 23256455)
18. Oh SJ, Jeltsch MM, Birkenhager R et al. 1997. VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane. Dev Biol 188: 96-109. (Pubitemid 27360090)
19. Ormerod MG, Orr RM, Peacock JH. 1994. The role of apoptosis in cell killing by cisplatin: a flow cytometric study. Br J Cancer 69: 93-100. (Pubitemid 24021828)
20. Perdue GP, Blomster RN, Blake DA, Farnsworth NR. 1979. South American plants II: taspine isolation and anti-inflammatory activity. J Pharm Sci 68: 124-126.
21. Porras-Reyes BH, Lewis WH, Roman J, Simchowitz L, Mustoe TA. 1993. Enhancement of wound healing by the alkaloid taspine defining mechanism of action. Proc Soc Exp Biol Med 203: 18-25. (Pubitemid 23122013)
22. Sa F, Gao JL, Fung KP, Zheng Y, Lee SM, Wang YT. 2008. Antiproliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. Chem Biol Interact 171: 1-14. (Pubitemid 350191844)
23. Searle J, Lawson TA, Abott PJ, Harmon B, Kerr JFR. 1974. An electron-microscope study of the mode of cell death induced by cancer chemotherapeutic agents in populations of proliferating normal and neoplastic cells. J Pathol 116: 129-138.
24. Sinha R, El-Bayoumy K. 2004. Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds. Curr Cancer Drug Targets 4: 13-28. (Pubitemid 38332561)
25. Sun JY, Zhu MZ, Wang SW, Miao S, Xie YH, Wang JB. 2007. Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine. Phytomedicine 14: 353-359. (Pubitemid 46654787)
26. Wang JH, Redmond HP, Watson RW, Bouchier-Hayes D. 1997. Induction of human endothelial cell apoptosis requires both heat shock and oxidative stress responses. Am J Physiol 272: C1543-C1551.
27. Wang Y, Sun LG, Xia CH, Ye LP, Wang B. 2009. P38MAPK regulates caspase-3 by binding to caspase-3 in nucleus of human hepatoma Bel-7402 cells during anti-Fas antibody and actinomycin D-induced apoptosis. Biomed Pharmacother 63: 343-350.
28. Wyllie AH. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556. (Pubitemid 10070336)
29. Wyllie AH, Morris RG, Smith AL, Dunlop D. 1984. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 142: 67-77. (Pubitemid 14151197)
30. Xiang M, Yang M, Zhou CH, Liu J, Li W, Qian Z. 2006. Crocetin prevents AGEs-induced vascular endothelial cell apoptosis. Pharmacol Res 54: 268-274. (Pubitemid 44233329)
31. Yang DS, Miao XD, Ye ZM et al. 2005. Bacterial redox protein azurin induce apoptosis in human osteosarcoma U2OS cells. Pharmacol Res 52: 413-421.
32. Zhang YM, He LC, Meng L, Luo WJ. 2008. Taspine isolated from Radix et Rhizoma Leonticis inhibits proliferation and migration of endothelial cells as well as chicken chorioallantoic membrane neovascularisation. Vascul Pharmacol 48: 129-137.
33. Zhang YM, He LC, Wang HY. 2007. Inhibitory effect of taspine on mouse S180 sarcoma and its mechanism. Zhongguo Zhong Yao Za Zhi 32: 27-30.