메뉴 건너뛰기




Volumn 8, Issue 1, 2011, Pages

Coding region, the neglected post-transcriptional code

Author keywords

Coding region; Mammalian post transcriptional gene expression; microRNAs; mRNA turnover; Polysomes; RNA binding proteins; Translation

Indexed keywords

CIS ACTING ELEMENT; MESSENGER RNA; MICRORNA; RNA BINDING PROTEIN; FMR1 PROTEIN, HUMAN; FRAGILE X MENTAL RETARDATION PROTEIN; RNA INDUCED SILENCING COMPLEX;

EID: 79952208881     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.8.1.13863     Document Type: Review
Times cited : (33)

References (45)
  • 2
    • 0037154982 scopus 로고    scopus 로고
    • A unified theory of gene expression
    • DOI 10.1016/S0092-8674(02)00655-4
    • Orphanides G, Reinberg D. A unified theory of gene expression. Cell 2002; 108:439-51. (Pubitemid 34260870)
    • (2002) Cell , vol.108 , Issue.4 , pp. 439-451
    • Orphanides, G.1    Reinberg, D.2
  • 3
    • 24644502657 scopus 로고    scopus 로고
    • From birth to death: The complex lives of eukaryotic mRNAs
    • DOI 10.1126/science.1111443
    • Moore MJ. From birth to death: the complex lives of eukaryotic mRNAs. Science 2005; 309:1514-8. (Pubitemid 41266467)
    • (2005) Science , vol.309 , Issue.5740 , pp. 1514-1518
    • Moore, M.J.1
  • 4
    • 40149096226 scopus 로고    scopus 로고
    • Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: Implications for cellular senescence
    • DOI 10.1515/BC.2008.022
    • Abdelmohsen K, Kuwano Y, Kim HH, Gorospe M. Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem 2008; 389:243-55. (Pubitemid 351329020)
    • (2008) Biological Chemistry , vol.389 , Issue.3 , pp. 243-255
    • Abdelmohsen, K.1    Kuwano, Y.2    Kim, H.H.3    Gorospe, M.4
  • 5
    • 44449166478 scopus 로고    scopus 로고
    • RNA-binding proteins and post-transcriptional gene regulation
    • Glisovic T, Bachorik JL, Yong J, Dreyfuss G. RNA-binding proteins and post-transcriptional gene regulation. FEBS Lett 2008; 582:1977-86.
    • (2008) FEBS Lett , vol.582 , pp. 1977-1986
    • Glisovic, T.1    Bachorik, J.L.2    Yong, J.3    Dreyfuss, G.4
  • 6
    • 12344281782 scopus 로고    scopus 로고
    • The implications of structured 5′ untranslated regions on translation and disease
    • DOI 10.1016/j.semcdb.2004.11.006, PII S1084952104001107, Protein Synthesis in Health and Disease
    • Pickering BM, Willis AE. The implications of structured 5′ untranslated regions on translation and disease. Semin Cell Dev Biol 2005; 16:39-47. (Pubitemid 40126875)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.1 , pp. 39-47
    • Pickering, B.M.1    Willis, A.E.2
  • 8
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • Fabian MR, Sonenberg N, Filipowicz W. Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 2010; 79:351-79.
    • (2010) Annu Rev Biochem , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 9
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136:215-33.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 10
    • 43449090367 scopus 로고    scopus 로고
    • MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation
    • Ørom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5′UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell 2008; 30:460-71.
    • (2008) Mol Cell , vol.30 , pp. 460-471
    • Ørom, U.A.1    Nielsen, F.C.2    Lund, A.H.3
  • 11
    • 74049111298 scopus 로고    scopus 로고
    • Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs
    • Marasa BS, Srikantan S, Masuda K, Abdelmohsen K, Kuwano Y, Yang X, et al. Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs. Sci Signal 2009; 2:69.
    • (2009) Sci Signal , vol.2 , pp. 69
    • Marasa, B.S.1    Srikantan, S.2    Masuda, K.3    Abdelmohsen, K.4    Kuwano, Y.5    Yang, X.6
  • 13
    • 4143122397 scopus 로고    scopus 로고
    • Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
    • DOI 10.1038/sj.emboj.7600305
    • Lal A, Mazan-Mamczarz K, Kawai T, Yang X, Martindale JL, Gorospe M. Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J 2004; 23:3092-102. (Pubitemid 39093603)
    • (2004) EMBO Journal , vol.23 , Issue.15 , pp. 3092-3102
    • Lal, A.1    Mazan-Mamczarz, K.2    Kawai, T.3    Yang, X.4    Martindale, J.L.5    Gorospe, M.6
  • 14
    • 34249875986 scopus 로고    scopus 로고
    • Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
    • DOI 10.1038/nsmb1249, PII NSMB1249
    • Liao B, Hu Y, Brewer G. Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat Struct Mol Biol 2007; 14:511-8. (Pubitemid 46871812)
    • (2007) Nature Structural and Molecular Biology , vol.14 , Issue.6 , pp. 511-518
    • Liao, B.1    Hu, Y.2    Brewer, G.3
  • 15
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress
    • DOI 10.1016/j.cell.2006.04.031, PII S0092867406005800
    • Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 2006; 125:1111-24. (Pubitemid 43866197)
    • (2006) Cell , vol.125 , Issue.6 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3    Closs, E.I.4    Filipowicz, W.5
  • 17
    • 0242669945 scopus 로고    scopus 로고
    • Regulation of mRNA translation by 5′- And 3′-UTR-binding factors
    • DOI 10.1016/S0968-0004(03)00051-3
    • Wilkie GS, Dickson KS, Gray NK. Regulation of mRNA translation by 5′- and 3′-UTR-binding factors. Trends Biochem Sci 2003; 28:182-8. (Pubitemid 36507156)
    • (2003) Trends in Biochemical Sciences , vol.28 , Issue.4 , pp. 182-188
    • Wilkie, G.S.1    Dickson, K.S.2    Gray, N.K.3
  • 18
    • 57349138816 scopus 로고    scopus 로고
    • Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins
    • Vlasova IA, Bohjanen PR. Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins. RNA Biol 2008; 5:201-7.
    • (2008) RNA Biol , vol.5 , pp. 201-207
    • Vlasova, I.A.1    Bohjanen, P.R.2
  • 19
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: Are there unifying principles?
    • Barreau C, Paillard L, Osborne HB. AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res 2006; 33:7138-50.
    • (2006) Nucleic Acids Res , vol.33 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 21
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 2009; 324:218-23.
    • (2009) Science , vol.324 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.3    Weissman, J.S.4
  • 22
    • 0026507321 scopus 로고
    • Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant
    • Bernstein PL, Herrick DJ, Prokipcak RD, Ross J. Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant. Genes Dev 1992; 6:642-54.
    • (1992) Genes Dev , vol.6 , pp. 642-654
    • Bernstein, P.L.1    Herrick, D.J.2    Prokipcak, R.D.3    Ross, J.4
  • 23
    • 0026026139 scopus 로고
    • The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors
    • Wisdom R, Lee W. The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors. Genes Dev 1991; 5:232-43. (Pubitemid 21905948)
    • (1991) Genes and Development , vol.5 , Issue.2 , pp. 232-243
    • Wisdom, R.1    Lee, W.2
  • 24
    • 0028212864 scopus 로고
    • The half-life of c-myc mRNA in growing and serum-stimulated cells: Influence of the coding and 3' untranslated regions and role of ribosome translocation
    • Herrick DJ, Ross J. The half-life of c-myc mRNA in growing and serum-stimulated cells: influence of the coding and 3' untranslated regions and role of ribosome translocation. Mol Cell Biol 1994; 14:2119-28.
    • (1994) Mol Cell Biol , vol.14 , pp. 2119-2128
    • Herrick, D.J.1    Ross, J.2
  • 25
    • 0032546790 scopus 로고    scopus 로고
    • C-myc mRNA is down-regulated during myogenic differentiation by accelerated decay that depends on translation of regulatory coding elements
    • DOI 10.1074/jbc.273.25.15749
    • Yeilding NM, Procopio WN, Rehman MT, Lee WM. c-myc mRNA is downregulated during myogenic differentiation by accelerated decay that depends on translation of regulatory coding elements. J Biol Chem 1998; 273:15749-57. (Pubitemid 28298195)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.25 , pp. 15749-15757
    • Yeilding, N.M.1    Procopio, W.N.2    Rehman, M.T.3    Lee, W.M.F.4
  • 26
    • 0032533776 scopus 로고    scopus 로고
    • The c-myc coding region determinant-binding protein: A member of a family of KH domain RNA-binding proteins
    • Doyle GA, Betz NA, Leeds PF, Fleisig AJ, Prokipcak RD, Ross J. The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins. Nucleic Acids Res 1998; 26:5036-44. (Pubitemid 28517556)
    • (1998) Nucleic Acids Research , vol.26 , Issue.22 , pp. 5036-5044
    • Doyle, G.A.R.1    Betz, N.A.2    Leeds, P.F.3    Fleisig, A.J.4    Prokipcak, R.D.5    Ross, J.6
  • 28
    • 33745225167 scopus 로고    scopus 로고
    • CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling
    • Noubissi FK, Elcheva I, Bhatia N, Shakoori A, Ougolkov A, Liu J, et al. CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. Nature 2006; 441:898-901.
    • (2006) Nature , vol.441 , pp. 898-901
    • Noubissi, F.K.1    Elcheva, I.2    Bhatia, N.3    Shakoori, A.4    Ougolkov, A.5    Liu, J.6
  • 29
    • 77953267727 scopus 로고    scopus 로고
    • The developmental roles of FMRP
    • Till SM. The developmental roles of FMRP. Biochem Soc Trans 2010; 38:507-10.
    • (2010) Biochem Soc Trans , vol.38 , pp. 507-510
    • Till, S.M.1
  • 30
    • 33947195786 scopus 로고    scopus 로고
    • FMRP mediates mGluR5-dependent translation of amyloid precursor protein
    • Westmark CJ, Malter JS. FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol 2007; 5:52.
    • (2007) PLoS Biol , vol.5 , pp. 52
    • Westmark, C.J.1    Malter, J.S.2
  • 32
    • 0033557935 scopus 로고    scopus 로고
    • unr, a cellular cytoplasmic RNA-binding protein with five coldshock domains, is required for internal initiation of translation of human rhinovirus RNA
    • Hunt SL, Hsuan JJ, Totty N, Jackson RJ. unr, a cellular cytoplasmic RNA-binding protein with five coldshock domains, is required for internal initiation of translation of human rhinovirus RNA. Genes Dev 1999; 15:437-8.
    • (1999) Genes Dev , vol.15 , pp. 437-438
    • Hunt, S.L.1    Hsuan, J.J.2    Totty, N.3    Jackson, R.J.4
  • 33
    • 4043062382 scopus 로고    scopus 로고
    • UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant
    • DOI 10.1101/gad.1219104
    • Chang TC, Yamashita A, Chen CY, Yamashita Y, Zhu W, Durdan S, et al. UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. Genes Dev 2004; 18:2010-23. (Pubitemid 39071582)
    • (2004) Genes and Development , vol.18 , Issue.16 , pp. 2010-2023
    • Chang, T.-C.1    Yamashita, A.2    Chen, C.-Y.A.3    Yamashita, Y.4    Zhu, W.5    Durdan, S.6    Kahvejian, A.7    Sonenberg, N.8    Shyu, A.-B.9
  • 34
    • 0035813219 scopus 로고    scopus 로고
    • A coding region determinant of instability regulates levels of manganese superoxide dismutase mRNA
    • Davis CA, Monnier JM, Nick HS. A coding region determinant of instability regulates levels of manganese superoxide dismutase mRNA. J Biol Chem 2001; 276:37317-26.
    • (2001) J Biol Chem , vol.276 , pp. 37317-37326
    • Davis, C.A.1    Monnier, J.M.2    Nick, H.S.3
  • 35
    • 0035957987 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor type 2 contains mRNA instability elements within exon 4 of the coding region. Sequence homology to coding region instability determinants in other mRNAs
    • Tierney MJ, Medcalf RL. Plasminogen activator inhibitor type 2 contains mRNA instability elements within exon 4 of the coding region. Sequence homology to coding region instability determinants in other mRNAs. J Biol Chem 2001; 276:13675-84.
    • (2001) J Biol Chem , vol.276 , pp. 13675-13684
    • Tierney, M.J.1    Medcalf, R.L.2
  • 36
    • 0032941747 scopus 로고    scopus 로고
    • Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements
    • Dibbens JA, Miller DL, Damert A, Risau W, Vadas MA, Goodall GJ. Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements. Mol Biol Cell 1999; 10:907-19. (Pubitemid 29193720)
    • (1999) Molecular Biology of the Cell , vol.10 , Issue.4 , pp. 907-919
    • Dibbens, J.A.1    Miller, D.L.2    Damert, A.3    Risau, W.4    Vadas, M.A.5    Goodall, G.J.6
  • 38
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
    • Forman JJ, Legesse-Miller A, Coller HA. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci USA 2008; 105:14879-84.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 39
    • 77953563697 scopus 로고    scopus 로고
    • The code within the code: MicroRNAs target coding regions
    • Forman JJ, Coller HA. The code within the code: microRNAs target coding regions. Cell Cycle 2010; 9:1533-41.
    • (2010) Cell Cycle , vol.9 , pp. 1533-1541
    • Forman, J.J.1    Coller, H.A.2
  • 40
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
    • Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008; 455:1124-8.
    • (2008) Nature , vol.455 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3    Lim, B.4    Rigoutsos, I.5
  • 43
    • 58149511991 scopus 로고    scopus 로고
    • miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels
    • Abdelmohsen K, Srikantan S, Kuwano Y, Gorospe M. miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc Natl Acad Sci USA 2008; 105:20297-302.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20297-20302
    • Abdelmohsen, K.1    Srikantan, S.2    Kuwano, Y.3    Gorospe, M.4
  • 44
    • 78651302621 scopus 로고    scopus 로고
    • MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions
    • In press
    • Huang S, Wu S, Ding J, Lin J, Wei L, Gu J, et al. MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regions. Nucleic Acids Res 2010; In press.
    • (2010) Nucleic Acids Res
    • Huang, S.1    Wu, S.2    Ding, J.3    Lin, J.4    Wei, L.5    Gu, J.6
  • 45
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • Chi SW, Zang JB, Mele A, Darnell RB. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 2009; 460:479-86.
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.