Chemoprotective effect of the tetrahydrofuran lignan grandisin in the in-vivo rodent micronucleus assay

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 3, 2011, Pages 447-451

  Valadares, Marize C ^a   De Oliveira Júnior, Luiz Marcos ^a   De Carvalho, Flávio S ^a   Andrade, Lorenna V S ^a   Dos Santos, Alexandre P ^a   De Oliveira, Valéria ^a   De Souza Gil, Eric ^a   Kato, Massuo J ^b  

^a FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antimutagenic; Grandisin; Lignan; Micronucleus

Indexed keywords

ANTIMUTAGENIC AGENT; CYCLOPHOSPHAMIDE; GRANDISIN; LIGNAN DERIVATIVE; TETRAHYDROFURAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW; CELL PROTECTION; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DNA DAMAGE; DOSE RESPONSE; DRUG ACTIVATION; DRUG CYTOTOXICITY; DRUG EFFECT; ELECTROCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; MUTAGENICITY; NONHUMAN;

ADMINISTRATION, ORAL; ANIMALS; BONE MARROW CELLS; CYCLOPHOSPHAMIDE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FURANS; LIGNANS; MALE; MICE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS;

EID: 79952205097     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2010.01200.x     Document Type: Article

References (32)

1. Holland N et al. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps. Mutat Res 2008; 659: 93-108.
2. Duthie SJ. Berry phytochemicals, genomic stability and cancer: evidence for chemoprotection at several stages in the carcinogenic process. Mol Nutr Food Res 2007; 56: 665-674. (Pubitemid 47083677)
3. Chin Y-W et al. Lignans and other constituents of the fruits of Euterpe oleracea (Açai) with antioxidant and cytoprotective activities. J Agric Food Chem 2008; 56: 7759-7764.
4. Fiorentino A et al. Potential food additives from Carex distachya roots: identification and in vitro antioxidant properties. J Agric Food Chem 2008; 56: 8218-8225.
5. Marino SD et al. Identification of minor secondary metabolites from the latex of Croton lechleri (Muell-Arg) and evaluation of their antioxidant activity. Molecules 2008; 13: 1219-1229.
6. Ono M et al. DPPH radical-scavenging effect on some constituents from the aerial parts of Lippia triphylla. J Nat Med 2008; 62: 101-106. (Pubitemid 351176909)
7. Saladino R et al. Advances and challenges in the synthesis of highly oxidised natural phenols with antiviral, antioxidant and cytotoxic activities. Curr Med Chem 2008; 15: 1500-1519. (Pubitemid 351997782)
8. Rezende KR et al. Antioxidant activity of aryltetralone lignans and derivatives from Virola sebifera (Aubl.). Nat Prod Res 2005; 19: 661-666. (Pubitemid 41223448)
9. Lopes NP et al. Flavonoids and lignans from Virola surinamensis twigs and their in vitro activity against Trypanosoma cruzi. Planta Med 1998; 64: 667-668.
10. Lopes NP et al. Antimalarial use of volatile oil from leaves of Virola surinamensis (Rol.) Warb. by Waiãpi Amazon Indians. J Ethnopharmacol 1999; 67: 13-19.
11. Martins RC et al. Phenylpropanoids and tetrahydrofuran lignans from Piper solmsianum. Phytochemistry 2000; 55: 843-846.
12. Martins RC et al. Trypanocidal tetrahydrofuran lignans from inflorescences of Piper solmsianum. Phytochemistry 2003; 55: 667-670. (Pubitemid 37168994)
13. Bernardes LS et al. Synthesis and trypanocidal activity of 1,4- bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol and 1,4-bis-(3,4- dimethoxyphenyl)-1,4-butanediol. Bioorg Med Chem 2006; 14: 7075-7082. (Pubitemid 44403120)
14. Cabral MM et al. Larvicidal activity of grandisin against Aedes aegypti. J Am Mosq Control Assoc 2009; 25: 103-105.
15. Nogueira CD et al. Disruption of Chrysomya megacephala growth caused by lignan grandisin. J Med Entomol 2009; 46: 281-283.
16. Carvalho AA et al. Antinociceptive and antiinflammatory activities of grandisin extracted from Virola surinamensis. Phytother Res 2010; 24: 113-118.
17. Valadares MC et al. Cytotoxicity and antiangiogenic activity of grandisin. J Pharm Pharmacol 2009; 61: 1709-1714.
18. Figueiredo RC. Effects of grandisin on hematopoietic system in mice. Ribeirão Preto, São Paulo, Brazil: Universidade de São Paulo, 2006 (dissertation).
19. Smith RV, Rosazza JP. Microbial models for drug metabolism. Adv Appl Microbiol 1979; 25: 169-208.
20. Azerad R. Microbial models for drug metabolism. Adv Biochem Eng Biotechnol 1999; 63: 169-218.
21. Cunha CRM. Bioconversão: avaliação da capacidade de fungos filamentosos em metabolizar os substratos grandisina, naringina e naringenina. Goiânia, Goiás, Brazil: Universidade Federal de Goiás, 2008 (dissertation).
22. Asha S, Vidyavathi M. Cunninghamella - a microbial model for drug metabolism studies - a review. Biotechnol Adv 2009; 27: 16-29.
23. Barbosa-Filho JM et al. Neolignans from Licaria aurea. Phytochemistry 1989; 28: 2209-2221.
24. Olfert ED et al. eds. Guide to the Care and Use of Experimental Animals, Vol. 1, 2nd edn. Ottawa: Canadian Council on Animal Care, 1993: 212.
25. MacGregor JT et al. Guidelines for the conduct of micronucleus assay in mammalian bone marrow erythrocytes. Mutat Res 1987; 189: 103-112. (Pubitemid 17144425)
26. Pereira CAB. Teste estatístico para comparar proporçõ es em problemas de citogenética. In: Rabello-Gay MN et al. eds. Mutagênese, Teratogênese e Carcinomatous, Métodos e Critérios de Avaliação. São Paulo, FCA: 113-121.
27. Manoharan K, Banerjee MR. b-Carotene reduces sister chromatid exchange induce chemical carcinogens in mouse mammary cells in organ culture. Cell Biol Int Rep 1985; 9: 783-789. (Pubitemid 15024182)
28. Valadares MC et al. Protective effects of 4-nerolidylcatechol against genotoxicity induced by cyclophosphamide. Food Chem Toxicol 2007; 45: 1975-1978. (Pubitemid 47238212)
29. Kouzi SA, McChesney JD. Microbial models of mammalian metabolism: fungal metabolism of the diterpene sclareol by Cunninghamella species. J Nat Prod 1991; 54: 483-490.
30. Gordaliza M et al. Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives. Toxicon 2004; 44: 441-459. (Pubitemid 39070644)
31. Yang CS et al. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu Rev Nutr 2001; 21: 381-406. (Pubitemid 32695277)
32. Ramos CS et al. Metabolism of (-)-grandisin from Piper solmsianum in Coleoptera and Lepidoptera species. Phytochemistry 2008; 69: 2157-2161.