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Volumn 695, Issue , 2011, Pages 243-259

Assessment of Nanomaterials Cytotoxicity and Internalization

Author keywords

Cytotoxicity; Endocytic effectors; Endocytosis; Internalization; Microfluorimetry; Nanotechnology

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; NANOPARTICLE;

EID: 79952202001     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60761-984-0_16     Document Type: Chapter
Times cited : (6)

References (59)
  • 1
    • 27844463051 scopus 로고    scopus 로고
    • Nanotechnology for drug and gene therapy: The importance of understanding molecular mechanisms of delivery
    • Labhasetwar, V. (2005) Nanotechnology for drug and gene therapy: the importance of understanding molecular mechanisms of delivery. Curr. Opin. Biotechnol. 16, 674–680.
    • (2005) Curr. Opin. Biotechnol. , vol.16 , pp. 674-680
    • Labhasetwar, V.1
  • 2
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner, S. D. and Schmid, S. L. (2003) Regulated portals of entry into the cell. Nature 422, 37–44.
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 3
    • 44849138911 scopus 로고    scopus 로고
    • Intracellular delivery of nanoparticles with biological systems
    • Surti, N., Naik, S., Bagchi, T., Garcion, E., and Misra, A. (2008) Intracellular delivery of nanoparticles with biological systems. Biomaterials 9, 217–223.
    • (2008) Biomaterials , vol.9 , pp. 217-223
    • Surti, N.1    Naik, S.2    Bagchi, T.3    Garcion, E.4    Misra, A.5
  • 4
    • 44849138911 scopus 로고    scopus 로고
    • Intracellular delivery of nanoparticles of an antiasthmatic drug
    • Basarkar, A. and Misra, A. (2008) Intracellular delivery of nanoparticles of an antiasthmatic drug. AAPS PharmSciTech 9, 217–223.
    • (2008) AAPS Pharmscitech , vol.9 , pp. 217-223
    • Basarkar, A.1    Misra, A.2
  • 6
    • 34548324409 scopus 로고    scopus 로고
    • Preparation, characterization, cytotoxicity and transfection efficiency of poly(d,l-lactide-co-glycolide) and poly(dl-lactic acid) cationic nanoparticles for controlled delivery of plasmid DNA
    • Basarkar, A., Devineni, D., Palaniappan, R., and Singh, J. (2007) Preparation, characterization, cytotoxicity and transfection efficiency of poly(d,l-lactide-co-glycolide) and poly(dl-lactic acid) cationic nanoparticles for controlled delivery of plasmid DNA. Int. J. Pharm. 343, 247–254.
    • (2007) Int. J. Pharm. , vol.343 , pp. 247-254
    • Basarkar, A.1    Devineni, D.2    Palaniappan, R.3    Singh, J.4
  • 7
    • 33846677328 scopus 로고    scopus 로고
    • Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles
    • Lee, M.-K., Lim, S.-J., and Kim, C.-K. (2007) Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles. Biomaterials 28, 2137–2146.
    • (2007) Biomaterials , vol.28 , pp. 2137-2146
    • Lee, M.-K.1    Lim, S.-J.2    Kim, C.-K.3
  • 8
    • 33845218637 scopus 로고    scopus 로고
    • In vitro toxicity of silica nanoparticles in human lung cancer cells
    • Lin, W., Huang, Y.-W., Zhou, X.-D., and Ma, Y. (2006) In vitro toxicity of silica nanoparticles in human lung cancer cells. Toxicol. Appl. Pharmacol. 217, 252–259.
    • (2006) Toxicol. Appl. Pharmacol. , vol.217 , pp. 252-259
    • Lin, W.1    Huang, Y.-W.2    Zhou, X.-D.3    Ma, Y.4
  • 9
    • 33745904988 scopus 로고    scopus 로고
    • Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles
    • Azarmi, S., Tao, X., Chen, H., Wang, Z., Finlay, W. H., Lobenberg, R., and Roa, W. H. (2006) Formulation and cytotoxicity of doxorubicin nanoparticles carried by dry powder aerosol particles. Int. J. Pharm. 319, 155–161.
    • (2006) Int. J. Pharm. , vol.319 , pp. 155-161
    • Azarmi, S.1    Tao, X.2    Chen, H.3    Wang, Z.4    Finlay, W.H.5    Lobenberg, R.6    Roa, W.H.7
  • 10
    • 0042634190 scopus 로고    scopus 로고
    • Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(d,l-lactide-co-gly-colide) nanoparticles
    • Panyam, J., Sahoo, S. K., Prabha, S., Bargar, T., and Labhasetwar, V. (2003) Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(d,l-lactide-co-gly-colide) nanoparticles. Int. J. Pharm. 262, 1–11.
    • (2003) Int. J. Pharm. , vol.262 , pp. 1-11
    • Panyam, J.1    Sahoo, S.K.2    Prabha, S.3    Bargar, T.4    Labhasetwar, V.5
  • 11
    • 0036324712 scopus 로고    scopus 로고
    • Rapid endo-lysosomal escape of poly(d,l-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery
    • Panyam, J., Zhou, W. Z., Prabha, S., Sahoo, S. K., and Labhasetwar, V. (2002) Rapid endo-lysosomal escape of poly(d,l-lactide-co-glycolide) nanoparticles: implications for drug and gene delivery. FASEB J. 16, 1217–1226.
    • (2002) FASEB J , vol.16 , pp. 1217-1226
    • Panyam, J.1    Zhou, W.Z.2    Prabha, S.3    Sahoo, S.K.4    Labhasetwar, V.5
  • 12
    • 0037148662 scopus 로고    scopus 로고
    • Characterization of nanoparticle uptake by endothelial cells
    • Davda, J. and Labhasetwar, V. (2002) Characterization of nanoparticle uptake by endothelial cells. Int. J. Pharm. 233, 51–59.
    • (2002) Int. J. Pharm. , vol.233 , pp. 51-59
    • Davda, J.1    Labhasetwar, V.2
  • 13
    • 0032472243 scopus 로고    scopus 로고
    • Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative
    • Kawaura, C., Noguchi, A., Furuno, T., and Nakanishi, M. (1998) Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative. FEBS Lett. 421, 69–72.
    • (1998) FEBS Lett , vol.421 , pp. 69-72
    • Kawaura, C.1    Noguchi, A.2    Furuno, T.3    Nakanishi, M.4
  • 14
    • 31644440095 scopus 로고    scopus 로고
    • Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging
    • Huth, U. S., Schubert, R., and Peschka-Suss, R. (2006) Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging, J. Control Release 110, 490–504.
    • (2006) J. Control Release , vol.110 , pp. 490-504
    • Huth, U.S.1    Schubert, R.2    Peschka-Suss, R.3
  • 15
    • 0035500592 scopus 로고    scopus 로고
    • On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes
    • Simoes, S., Slepushkin, V., Duzgunes, N., and Pedroso de Lima, M. C. (2001) On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes. Biochim. Biophys. Acta 1515, 23–37.
    • (2001) Biochim. Biophys. Acta , vol.1515 , pp. 23-37
    • Simoes, S.1    Slepushkin, V.2    Duzgunes, N.3    Pedroso de Lima, M.C.4
  • 16
    • 0037331856 scopus 로고    scopus 로고
    • Dynamics of endocytosis and exocytosis of poly(d,l-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells
    • Panyam, J. and Labhasetwar, V. (2003) Dynamics of endocytosis and exocytosis of poly(d,l-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells. Pharm. Res. 20, 212–220.
    • (2003) Pharm. Res. , vol.20 , pp. 212-220
    • Panyam, J.1    Labhasetwar, V.2
  • 17
    • 31644440095 scopus 로고    scopus 로고
    • Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging
    • Huth, U. S., Schubert, R., and Peschka-Süss, R. (2006) Investigating the uptake and intracellular fate of pH-sensitive liposomes by flow cytometry and spectral bio-imaging. J. Control Release 110, 490–504.
    • (2006) J. Control Release , vol.110 , pp. 490-504
    • Huth, U.S.1    Schubert, R.2    Peschka-Süss, R.3
  • 19
    • 4143135338 scopus 로고    scopus 로고
    • Folate-mediated cell targeting and cytotoxicity using thermoresponsive microgels
    • Nayak, S., Lee, H., Chmielewski, J., and Lyon, L. A. (2004) Folate-mediated cell targeting and cytotoxicity using thermoresponsive microgels. J. Am. Chem. Soc. 126, 10258–10259.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 10258-10259
    • Nayak, S.1    Lee, H.2    Chmielewski, J.3    Lyon, L.A.4
  • 20
    • 0036529653 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis of phosphodiester oligonucle-otides in the HepG2 cell line: Evidence for non-conventional intracellular trafficking
    • de Diesbach, P., N’Kuli, F., Berens, C., Sonveaux, E., Monsigny, M., Roche, A. C., and Courtoy, P. J. (2002) Receptor-mediated endocytosis of phosphodiester oligonucle-otides in the HepG2 cell line: evidence for non-conventional intracellular trafficking. Nucleic Acids Res. 30, 1512–1521.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1512-1521
    • de Diesbach, P.1    N’Kuli, F.2    Berens, C.3    Sonveaux, E.4    Monsigny, M.5    Roche, A.C.6    Courtoy, P.J.7
  • 21
    • 20744454954 scopus 로고    scopus 로고
    • Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium
    • des Rieux, A., Ragnarsson, E. G., Gullberg, E., Preat, V., Schneider, Y. J., and Artursson, P. (2005) Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium. Eur. J. Pharm. Sci. 25, 455–465.
    • (2005) Eur. J. Pharm. Sci , vol.25 , pp. 455-465
    • des Rieux, A.1    Ragnarsson, E.G.2    Gullberg, E.3    Preat, V.4    Schneider, Y.J.5    Artursson, P.6
  • 22
    • 33748917630 scopus 로고    scopus 로고
    • Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts
    • Kim, S. H., Choi, H. J., Lee, K. W., Hong, N. H., Sung, B. H., Choi, K. Y., Kim, S. M., Chang, S., Eom, S. H., and Song, W. K. (2006) Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts. Genes Cells 11, 1197–1211.
    • (2006) Genes Cells , vol.11 , pp. 1197-1211
    • Kim, S.H.1    Choi, H.J.2    Lee, K.W.3    Hong, N.H.4    Sung, B.H.5    Choi, K.Y.6    Kim, S.M.7    Chang, S.8    Eom, S.H.9    Song, W.K.10
  • 23
    • 33845914055 scopus 로고    scopus 로고
    • Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells
    • Kahn, E., Menetrier, F., Vejux, A., Montange, T., Dumas, D., Riedinger, J. M., Frouin, F., Tourneur, Y., Brau, F., Stoltz, J. F., and Lizard, G. (2006) Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells. Anal. Quant. Cytol. Histol. 28, 316–330.
    • (2006) Anal. Quant. Cytol. Histol. , vol.28 , pp. 316-330
    • Kahn, E.1    Menetrier, F.2    Vejux, A.3    Montange, T.4    Dumas, D.5    Riedinger, J.M.6    Frouin, F.7    Tourneur, Y.8    Brau, F.9    Stoltz, J.F.10    Lizard, G.11
  • 24
    • 24344471360 scopus 로고    scopus 로고
    • Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate
    • Mo, Y. and Lim, L. Y. (2005) Preparation and in vitro anticancer activity of wheat germ agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and isopropyl myristate. J. Control Release 107, 30–42.
    • (2005) J. Control Release , vol.107 , pp. 30-42
    • Mo, Y.1    Lim, L.Y.2
  • 26
    • 33344467489 scopus 로고    scopus 로고
    • Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system
    • Amidi, M., Romeijn, S. G., Borchard, G., Junginger, H. E., Hennink, W. E., and Jiskoot, W. (2006) Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. J. Control Release 111, 107–116.
    • (2006) J. Control Release , vol.111 , pp. 107-116
    • Amidi, M.1    Romeijn, S.G.2    Borchard, G.3    Junginger, H.E.4    Hennink, W.E.5    Jiskoot, W.6
  • 27
    • 0031889295 scopus 로고    scopus 로고
    • FITC-poly-d-lysine conjugates as fluorescent probes to quantify hapten-specific macrophage receptor binding and uptake kinetics
    • Cherukuri, A., Frye, J., French, T., Durack, G., and Voss, E. W. Jr. (1998) FITC-poly-d-lysine conjugates as fluorescent probes to quantify hapten-specific macrophage receptor binding and uptake kinetics. Cytometry 31, 110–124.
    • (1998) Cytometry , vol.31 , pp. 110-124
    • Cherukuri, A.1    Frye, J.2    French, T.3    Durack, G.4    Voss, E.W.5
  • 28
    • 0036804673 scopus 로고    scopus 로고
    • Uptake of FITC-chitosan nanoparticles by A549 cells
    • Huang, M., Ma, Z., Khor, E., and Lim, L. Y. (2002) Uptake of FITC-chitosan nanoparticles by A549 cells. Pharm. Res. 19, 1488–1494.
    • (2002) Pharm. Res. , vol.19 , pp. 1488-1494
    • Huang, M.1    Ma, Z.2    Khor, E.3    Lim, L.Y.4
  • 29
    • 23844462026 scopus 로고    scopus 로고
    • Role of clathrin-and caveolae-medi-ated endocytosis in gene transfer mediated by lipo-and polyplexes
    • Rejman, J., Bragonzi, A., and Conese, M. (2005) Role of clathrin-and caveolae-medi-ated endocytosis in gene transfer mediated by lipo-and polyplexes. Mol. Ther. 12, 468–474.
    • (2005) Mol. Ther. , vol.12 , pp. 468-474
    • Rejman, J.1    Bragonzi, A.2    Conese, M.3
  • 30
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan molecules and nanoparticles: Effects of molecular weight and degree of deacetylation
    • Huang, M., Khor, E., and Lim, L. Y. (2004) Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharm. Res. 21, 344–353.
    • (2004) Pharm. Res. , vol.21 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.Y.3
  • 31
    • 0344946091 scopus 로고    scopus 로고
    • Uptake of chitosan and associated insulin in Caco-2 cell monolayers: A comparison between chitosan molecules and chitosan nanoparticles
    • Ma, Z. and Lim, L. Y. (2003) Uptake of chitosan and associated insulin in Caco-2 cell monolayers: a comparison between chitosan molecules and chitosan nanoparticles. Pharm. Res. 20, 1812–1819.
    • (2003) Pharm. Res. , vol.20 , pp. 1812-1819
    • Ma, Z.1    Lim, L.Y.2
  • 33
    • 4744362333 scopus 로고    scopus 로고
    • Biglycan is internalized via a chlo-rpromazine-sensitive route
    • Gotte, M., Sofeu Feugaing, D. D., and Kresse, H. (2004) Biglycan is internalized via a chlo-rpromazine-sensitive route. Cell Mol. Biol. Lett. 9, 475–481.
    • (2004) Cell Mol. Biol. Lett. , vol.9 , pp. 475-481
    • Gotte, M.1    Sofeu Feugaing, D.D.2    Kresse, H.3
  • 34
    • 0346670126 scopus 로고    scopus 로고
    • Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: Role in PLGA nanoparticle endocytosis
    • Qaddoumi, M. G., Gukasyan, H. J., Davda, J., Labhasetwar, V., Kim, K. J., and Lee, V. H. (2003) Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis. Mol. Vis. 9, 559–568.
    • (2003) Mol. Vis. , vol.9 , pp. 559-568
    • Qaddoumi, M.G.1    Gukasyan, H.J.2    Davda, J.3    Labhasetwar, V.4    Kim, K.J.5    Lee, V.H.6
  • 35
    • 40349084220 scopus 로고    scopus 로고
    • Internalization of hydroxyapatite nanoparticles in liver cancer cells
    • Bauer, I. W., Li, S. P., Han, Y. C., Yuan, L., and Yin, M. Z. (2008) Internalization of hydroxyapatite nanoparticles in liver cancer cells. J. Mater. Sci. Mater. Med. 19, 1091–1095.
    • (2008) J. Mater. Sci. Mater. Med. , vol.19 , pp. 1091-1095
    • Bauer, I.W.1    Li, S.P.2    Han, Y.C.3    Yuan, L.4    Yin, M.Z.5
  • 36
    • 33747047847 scopus 로고    scopus 로고
    • Gene delivery by dendrimers operates via different pathways in different cells, but is enhanced by the presence of caveolin
    • Manunta, M., Nichols, B. J., Tan, P. H., Sagoo, P., Harper, J., and George, A. J. (2006) Gene delivery by dendrimers operates via different pathways in different cells, but is enhanced by the presence of caveolin. J. Immunol. Methods 314, 134–146.
    • (2006) J. Immunol. Methods , vol.314 , pp. 134-146
    • Manunta, M.1    Nichols, B.J.2    Tan, P.H.3    Sagoo, P.4    Harper, J.5    George, A.J.6
  • 37
    • 0032211844 scopus 로고    scopus 로고
    • Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction
    • Corvera, S. and Czech, M. P. (1998) Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction. Trends Cell Biol. 8, 442–446.
    • (1998) Trends Cell Biol , vol.8 , pp. 442-446
    • Corvera, S.1    Czech, M.P.2
  • 38
  • 40
    • 0029118603 scopus 로고
    • Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
    • Ui, M., Okada, T., Hazeki, K., and Hazeki, O. (1995) Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem. Sci. 20, 303–307.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 303-307
    • Ui, M.1    Okada, T.2    Hazeki, K.3    Hazeki, O.4
  • 42
    • 0021153906 scopus 로고
    • Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro
    • Dijkstra, J., Van Galen, M., and Scherphof, G. L. (1984) Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro. Biochim. Biophys. Acta. Mol. Cell Res. 804, 58–67.
    • (1984) Biochim. Biophys. Acta. Mol. Cell Res. , vol.804 , pp. 58-67
    • Dijkstra, J.1    van Galen, M.2    Scherphof, G.L.3
  • 43
    • 33748784063 scopus 로고    scopus 로고
    • Targeted gene delivery with trisaccharide-substituted chitosan oligomers in vitro and after lung administration in vivo
    • Issa, M. M., Koping-Hoggard, M., Tommeraas, K., Varum, K. M., Christensen, B. E., Strand, S. P., and Artursson, P. (2006) Targeted gene delivery with trisaccharide-substituted chitosan oligomers in vitro and after lung administration in vivo. J. Control Release 115, 103–112.
    • (2006) J. Control Release , vol.115 , pp. 103-112
    • Issa, M.M.1    Koping-Hoggard, M.2    Tommeraas, K.3    Varum, K.M.4    Christensen, B.E.5    Strand, S.P.6    Artursson, P.7
  • 44
    • 0026654763 scopus 로고
    • Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting
    • Hunziker, W., Whitney, J. A., and Mellman, I. (1992) Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting. FEBS Lett. 307, 93–96.
    • (1992) FEBS Lett , vol.307 , pp. 93-96
    • Hunziker, W.1    Whitney, J.A.2    Mellman, I.3
  • 45
    • 1842450748 scopus 로고    scopus 로고
    • The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers
    • Qaddoumi, M. G., Ueda, H., Yang, J., Davda, J., Labhasetwar, V., and Lee, V. H. (2004) The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers. Pharm. Res. 21, 641–648.
    • (2004) Pharm. Res. , vol.21 , pp. 641-648
    • Qaddoumi, M.G.1    Ueda, H.2    Yang, J.3    Davda, J.4    Labhasetwar, V.5    Lee, V.H.6
  • 46
    • 4344697827 scopus 로고    scopus 로고
    • Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells
    • Goncalves, C., Mennesson, E., Fuchs, R., Gorvel, J. P., Midoux, P., and Pichon, C. (2004) Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells. Mol. Ther. 10, 373–385.
    • (2004) Mol. Ther. , vol.10 , pp. 373-385
    • Goncalves, C.1    Mennesson, E.2    Fuchs, R.3    Gorvel, J.P.4    Midoux, P.5    Pichon, C.6
  • 47
    • 33645474488 scopus 로고    scopus 로고
    • Lactosylated chitosan for DNA delivery into hepatocytes: The effect of lactosylation on the physico-chemical properties and intracellular trafficking of pDNA/chitosan complexes
    • Hashimoto, M., Morimoto, M., Saimoto, H., Shigemasa, Y., and Sato, T. (2006) Lactosylated chitosan for DNA delivery into hepatocytes: the effect of lactosylation on the physico-chemical properties and intracellular trafficking of pDNA/chitosan complexes. Bioconj. Chem. 17, 309–316.
    • (2006) Bioconj. Chem. , vol.17 , pp. 309-316
    • Hashimoto, M.1    Morimoto, M.2    Saimoto, H.3    Shigemasa, Y.4    Sato, T.5
  • 48
    • 0021871305 scopus 로고
    • Effects of (dihydro)cytochalasin B, colchicine, monensin and trifluoperazine on uptake and processing of liposomes by Kupffer cells in culture
    • Dijkstra, J., van Galen, M., and Scherphof, G. (1985) Effects of (dihydro)cytochalasin B, colchicine, monensin and trifluoperazine on uptake and processing of liposomes by Kupffer cells in culture. Biochim. Biophys. Acta 845, 34–42.
    • (1985) Biochim. Biophys. Acta , vol.845 , pp. 34-42
    • Dijkstra, J.1    van Galen, M.2    Scherphof, G.3
  • 49
    • 0034118297 scopus 로고    scopus 로고
    • Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells
    • Ramge, P., Unger, R. E., Oltrogge, J. B., Zenker, D., Begley, D., Kreuter, J., and Von Briesen, H. (2000) Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells. Eur. J. Neurosci. 12, 1931–1940.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 1931-1940
    • Ramge, P.1    Unger, R.E.2    Oltrogge, J.B.3    Zenker, D.4    Begley, D.5    Kreuter, J.6    von Briesen, H.7
  • 50
    • 0020034982 scopus 로고
    • Microtubules and beta cell function: Effect of colchicine on microtubules and insulin secretion in vitro by mouse beta cells
    • Boyd, A. E. III, Bolton, W. E., and Brinkley, B. R. (1982) Microtubules and beta cell function: effect of colchicine on microtubules and insulin secretion in vitro by mouse beta cells. J. Cell Biol. 92, 425–434.
    • (1982) J. Cell Biol. , vol.92 , pp. 425-434
    • Boyd, A.E.1    Bolton, W.E.2    Brinkley, B.R.3
  • 51
    • 33847095924 scopus 로고    scopus 로고
    • Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells
    • Hu, Y., Xie, J., Tong, Y. W., and Wang, C.-H. (2007) Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells. J. Control Release 118, 7–17.
    • (2007) J. Control Release , vol.118 , pp. 7-17
    • Hu, Y.1    Xie, J.2    Tong, Y.W.3    Wang, C.-H.4
  • 52
    • 33846410672 scopus 로고    scopus 로고
    • Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery
    • Zhang, Z., Huey Lee, S., and Feng, S. S. (2007) Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery. Biomaterials 28, 1889–1899.
    • (2007) Biomaterials , vol.28 , pp. 1889-1899
    • Zhang, Z.1    Huey Lee, S.2    Feng, S.S.3
  • 53
    • 33748785439 scopus 로고    scopus 로고
    • N-acetyl histidine-conju-gated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: Endocytosis, exocytosis and drug release
    • Park, J. S., Han, T. H., Lee, K. Y., Han, S. S., Hwang, J. J., Moon, D. H., Kim, S. Y., and Cho, Y. W. (2006) N-acetyl histidine-conju-gated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release. J. Control Release 115, 37–45.
    • (2006) J. Control Release , vol.115 , pp. 37-45
    • Park, J.S.1    Han, T.H.2    Lee, K.Y.3    Han, S.S.4    Hwang, J.J.5    Moon, D.H.6    Kim, S.Y.7    Cho, Y.W.8
  • 54
    • 33644826104 scopus 로고    scopus 로고
    • In vitro uptake of gelatin nanoparticles by murine dendritic cells and their intracellular localisation
    • Coester, C., Nayyar, P., and Samuel, J. (2006) In vitro uptake of gelatin nanoparticles by murine dendritic cells and their intracellular localisation. Eur. J. Pharm. Biopharm. 62, 306–314.
    • (2006) Eur. J. Pharm. Biopharm. , vol.62 , pp. 306-314
    • Coester, C.1    Nayyar, P.2    Samuel, J.3
  • 55
    • 17644386231 scopus 로고    scopus 로고
    • Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
    • Richard, J. P., Melikov, K., Brooks, H., Prevot, P., Lebleu, B., and Chernomordik, L. V. (2005) Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J. Biol. Chem. 280, 15300–15306.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15300-15306
    • Richard, J.P.1    Melikov, K.2    Brooks, H.3    Prevot, P.4    Lebleu, B.5    Chernomordik, L.V.6
  • 56
    • 46549084447 scopus 로고    scopus 로고
    • The effect of surface functionality on cellular trafficking of dendrimers
    • Perumal, O. P., Inapagolla, R., Kannan, S., and Kannan, R. M. (2008) The effect of surface functionality on cellular trafficking of dendrimers. Biomaterials 29, 3469–3476.
    • (2008) Biomaterials , vol.29 , pp. 3469-3476
    • Perumal, O.P.1    Inapagolla, R.2    Kannan, S.3    Kannan, R.M.4
  • 57
    • 10044225776 scopus 로고    scopus 로고
    • Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs
    • Win, K. Y. and Feng, S. S. (2005) Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs. Biomaterials 26, 2713–2722.
    • (2005) Biomaterials , vol.26 , pp. 2713-2722
    • Win, K.Y.1    Feng, S.S.2
  • 58
    • 0032586956 scopus 로고    scopus 로고
    • Vitamin B12-mediated transport of nanoparticles across Caco-2 cells
    • Russell-Jones, G. J., Arthur, L., and Walker, H. (1999) Vitamin B12-mediated transport of nanoparticles across Caco-2 cells. Int. J. Pharm. 179, 247–255.
    • (1999) Int. J. Pharm. , vol.179 , pp. 247-255
    • Russell-Jones, G.J.1    Arthur, L.2    Walker, H.3
  • 59
    • 33947143588 scopus 로고    scopus 로고
    • Surfactant-polymer nanoparticles: A novel platform for sustained and enhanced cellular delivery of water-soluble molecules
    • Chavanpatil, M. D., Khdair, A., and Panyam, J. (2007) Surfactant-polymer nanoparticles: a novel platform for sustained and enhanced cellular delivery of water-soluble molecules. Pharm. Res. 24, 803–810.
    • (2007) Pharm. Res. , vol.24 , pp. 803-810
    • Chavanpatil, M.D.1    Khdair, A.2    Panyam, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.