The "Warfarin Window" in Pregnancy: The Importance of Half-life

Journal of Obstetrics and Gynaecology Canada

Volumn 32, Issue 10, 2010, Pages 988-989

  Walfisch, Asnat ^a   Koren, Gideon ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Anticoagulation; Pregnancy; Prosthetic valve; Warfarin; Warfarin embryopathy

Indexed keywords

HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; WARFARIN; ANTICOAGULANT AGENT;

ANTICOAGULANT THERAPY; ARTICLE; DRUG ABSORPTION; DRUG HALF LIFE; DRUG SUBSTITUTION; ELIMINATION HALF-LIFE; EMBRYOPATHY; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; PRACTICE GUIDELINE; PREGNANCY; BONE; CARTILAGE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FEMALE; FETUS DISEASE; HALF LIFE TIME; HEART VALVE PROSTHESIS; PREGNANCY COMPLICATION; PRENATAL DEVELOPMENT;

ANTICOAGULANTS; BONE AND BONES; CARTILAGE; FEMALE; FETAL DISEASES; GESTATIONAL AGE; HALF-LIFE; HEART VALVE PROSTHESIS; HEPARIN; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; WARFARIN;

EID: 79952200468     PISSN: 17012163     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1701-2163(16)34689-8     Document Type: Article

References (8)

1. Bates S.M., Greer I.A., Pabinger I., Sofaer S., Hirsh J. American College of Chest Physicians. Venous thromboembolism, thrombophilia, antithrombotic therapy, and pregnancy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2008, 133(6 Suppl):844S-886S. 8th ed.
2. Chan W.S., Anand S., Ginsberg J.S. Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature. Arch Intern Med 2000, 160:191-196.
3. Bonow R.O., Carabello B.A., Kanu C., de Leon A.C., Faxon D.P., Freed M.D., et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Circulation 2006, 114:e84-e231.
4. Ginsberg J.S., Barron W.M. Pregnancy and prosthetic heart valves. Lancet 1994, 344:1170-1172.
5. Hall J.G., Pauli R.M., Wilson K.M. Maternal and fetal sequelae of anticoagulation during pregnancy. Am J Med 1980, 68:122-140.
6. Meschengieser S.S., Fondevila C.G., Santarelli M.T., Lazzari M.A. Anticoagulation in pregnant women with mechanical heart valve prostheses. Heart 1999, 82:23-26.
7. Canadian Pharmacists Association Coumadin [warfarin] monograph. Compendium of pharmaceuticals and specialties 2010, CPA, Ottawa.
8. Goodman and Gilman's the pharmacological basis of therapeutics 2006, 1477. United States, McGraw-Hill. 11th ed. L.L. Brunton, J.S. Lazo, K.L. Parker (Eds.).