Immunologic Detection of Benzo(a)pyrene–DNA Adducts

Methods in Molecular Biology

Volumn 682, Issue , 2011, Pages 271-278

  Santella, Regina M ^a   Zhang, Yu Jing ^a  

^a Department of Medicine   (United States)

Author keywords

Benzo(a)pyrene; Benzo(a)pyrene diol epoxide; DNA adducts; Immunofluorescence; Immunohistochemistry; Immunoperoxidase; Polycyclic aromatic hydrocarbons

Indexed keywords

ANIMALIA;

BENZO(A)PYRENE DNA ADDUCT; BENZO(A)PYRENE-DNA ADDUCT; BENZO[A]PYRENE; PARAFFIN;

ARTICLE; DNA ADDUCT; ENZYME IMMUNOASSAY; FLUORESCENT ANTIBODY TECHNIQUE; FROZEN SECTION; HUMAN; IMMUNOLOGY; METHODOLOGY;

BENZO(A)PYRENE; DNA ADDUCTS; FLUORESCENT ANTIBODY TECHNIQUE; FROZEN SECTIONS; HUMANS; IMMUNOENZYME TECHNIQUES; PARAFFIN EMBEDDING;

EID: 79952200279     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60327-409-8_19     Document Type: Chapter

References (11)

1. Santella, R.M. (1999) Immunologic methods for detection of carcinogen-DNA damage in humans. Cancer Epidemiol. Biomarkers Prev. 8, 733–739.
2. Gammon, M.D., Santella, R.M., Neugut, A.I., Eng, S.M., Teitelbaum, S.L., Paykin, A. et al. (2002) Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts. Cancer Epidemiol. Biomarkers Prev. 11, 677–685.
3. Hsu, T.M., Zhang, Y.J., Santella, R.M. (1997) Immunoperoxidase quantitation of 4-aminobiphenyl-and polycyclic aromatic hydrocarbon-DNA adducts in exfoliated oral and urothelial cells of smokers and nonsmokers. Cancer Epidemiol. Biomarkers Prev. 6, 193–199.
4. Motykiewicz, G., Malusecka, E., Grzybowska, E., Chorazy, M., Zhang, Y.J., Perera, F.P. et al. (1995) Immunohistochemical quantitation of polycyclic aromatic hydrocarbon-DNA adducts in human lymphocytes. Cancer Res. 55, 1417–1422.
5. Chen, S.Y., Wang, L.Y., Lunn, R., Tsai, W.Y., Lee, P.H., Lee, C.S. et al. (2002) Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls. Int. J. Cancer 99, 14–21.
6. Poirier, M.C., Santella, R.M., Weinstein, I.B., Grunberger, D., Yuspa, S.H. (1080) Quantitation of benzo[a]pyrene-deoxyguanosine adducts by radioimmunoassay. Cancer Res. 40, 412–416.
7. Santella, R.M., Lin, C.D., Cleveland, W.L., Weinstein, I.B.. (1984) Monoclonal antibodies to DNA modified by a benzo[a]pyrene diol epoxide. Carcinogenesis 5, 373–377.
8. Santella, R.M., Weston, A., Perera, F.P., Trivers, G.T., Harris, C.C., Young, T.L. et al. (1988) Interlaboratory comparison of antisera and immunoassays for benzo(a)pyrene-diol-epoxide-I-modified DNA. Carcinogenesis 9, 1265–1269.
9. Santella, R.M., Gasparro, F.P., Hsieh, L.L. (1987) Quantitation of carcinogen-DNA adducts with monoclonal antibodies. Prog. Exp. Tumor Res. 31, 63–75.
10. Weston, A., Trivers, G., Vahakangas, K., Newman, M., Rowe, M. (1987) Detection of carcinogen-DNA adducts in human cells and antibodies to these adducts in human sera. Prog. Exp. Tumor Res. 31, 76–85.
11. Zhang, Y.J., Hsu, T.M., Santella, R.M. (1995) Immunoperoxidase detection of polycyclic aromatic hydrocarbon-DNA adducts in oral mucosa cells of smokers and nonsmokers. Cancer Epidemiol. Biomarkers Prev. 4, 133–138.