The study of the tumor stem cell properties of CD133+CD44+ cells in the human lung adenocarcinoma cell line A549

Cellular and Molecular Biology

Volumn 56, Issue SUPPL.1, 2010, Pages

  Zhang, H Z ^a   Lin, X G ^a   Hua, P ^a   Wang, M ^a   Ao, X ^a   Xiong, L H ^a   Wu, C ^b   Guo, J J ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Ganzhou People's Hospital   (China)

Author keywords

CD133; CD44; Lung cancer; Properties of tumor stem cells

Indexed keywords

CD133 ANTIGEN; CD44V ANTIGEN; GLYCOPROTEIN; HERMES ANTIGEN; LEUKOCYTE ANTIGEN; PEPTIDE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER STEM CELL; CARCINOGENESIS; CELL CLONE; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ADENOCARCINOMA; ANIMAL; CARCINOGEN TESTING; CLASSIFICATION; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; LUNG TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; RNA INTERFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR CELL LINE;

MUS MUSCULUS;

ADENOCARCINOMA; ANIMALS; ANTIGENS, CD; ANTIGENS, CD44; CARCINOGENICITY TESTS; CELL LINE, TUMOR; CELL PROLIFERATION; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOPROTEINS; HUMANS; INJECTIONS, SUBCUTANEOUS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASTIC STEM CELLS; PEPTIDES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 79952198934     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.1170/154     Document Type: Article

References (15)

1. Abraham, B.K., Fritz, P., McClellan, M., Hauptvogel, P., Athelogou, M. and Brauch, H., Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin Cancer Res 2005, 11: 1154-1159.
2. Cichy, J., Kulig, P. and Pure, E., Regulation of the release and function of tumor cell-derived soluble CD44. Biochim Biophys Acta 2005, 1745: 59-64.
3. Collins, A.T., Berry, P.A., Hyde, C., Stower, M.J. and Maitland, N.J., Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005, 65: 10946-10951.
4. Ibrahim, E.M., Stewart, R.L., Corke, K., Blackett, A.D., Tidy, J.A. and Wells, M., Upregulation of CD44 expression by interleukins 1, 4, and 13, transforming growth factor-beta1, estrogen, and progestogen in human cervical adenocarcinoma cell lines. Int J Gynecol Cancer 2006, 16: 1631-1642.
5. Liu, J. and Jiang, G., CD44 and hematologic malignancies. Cell Mol Immunol 2006, 3: 359-365.
6. Mongini, C., Ruybal, P., Gravisaco, M.J., Croci, M., Sanchez Lockhart, M., Fabris, V. and Waldner, A.C., Characterization of the immunophenotype and the metastatic properties of a murine T-lymphoma cell line. Unexpected expression of cytoplasmatic CD4. In Vitro Cell Dev Biol Anim 2001, 37: 499-504.
7. Nikolaeva, T.G., Dobrynin Ia, V., Akhundov, A.A., Prorokov, V.V. and Davydov, M.I., [DNA flow cytometry in the prognostication of certain malignant neoformations]. Vopr Onkol 2001, 47: 684-689.
8. O'Brien, C.A., Pollett, A., Gallinger, S. and Dick, J.E., A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007, 445: 106-110.
9. Richardson, G.D., Robson, C.N., Lang, S.H., Neal, D.E., Maitland, N.J. and Collins, A.T., CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci 2004, 117: 3539-3545.
10. Sato, K., Sakamoto, K. and Nakashima, T., Expression and distribution of CD44 and hyaluronic acid in human vocal fold mucosa. Ann Otol Rhinol Laryngol 2006, 115: 741-748.
11. Singh, S.K., Clarke, I.D., Terasaki, M., Bonn, V.E., Hawkins, C., Squire, J. and Dirks, P.B., Identification of a cancer stem cell in human brain tumors. Cancer Res 2003, 63: 5821-5828.
12. Uchida, N., Buck, D.W., He, D., Reitsma, M.J., Masek, M., Phan, T.V., Tsukamoto, A.S., Gage, F.H. and Weissman, I.L., Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A 2000, 97: 14720-14725.
13. Wei, Y.P., Wang, M., Hua, P., Wu, C., Cao, Y.K., Yang, Y.Q., Chen, J. and Zhang, H.Z., Expression of Tumor Stem Cell Marker CD133 in non-small Cell Lung Carcinoma and Its Clinical Significance. Journal of Sun Yat-Sen University:Medical Sciences 2008, 29: 312-316.
14. Yu, S., Zhang, J.Z., Zhao, C.L., Zhang, H.Y. and Xu, Q., Isolation and characterization of the CD133+ precursors from the ventricular zone of human fetal brain by magnetic affinity cell sorting. Biotechnol Lett 2004, 26: 1131-1136.
15. Zhang, H.Z., Li, H.G., Zhang, H., Zeng, Y.J., Shen, X.M. and Long, Q., The study of the expression of CD44v6 and CEA in lung cancer and its clinical significance. Guangdong Med 2001, 22: 911-912.