Effect of an emergency department sepsis protocol on the care of septic patients admitted to the intensive care unit

Canadian Journal of Emergency Medicine

Volumn 12, Issue 5, 2010, Pages 414-420

  Sweet, David D ^a   Jaswal, Dharmvir ^a   Fu, Winnie ^a   Bouchard, Matt ^a   Sivapalan, Praveena ^a   Rachel, Jen ^a   Chittock, Dean ^a  

^a VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

Early goal directed therapy; Emergency department; Sepsis protocol; Septic shock; Severe sepsis

Indexed keywords

ADULT; ANTIBIOTIC THERAPY; ARTERY CATHETER; ARTICLE; CANADA; CENTRAL VENOUS PRESSURE; CLINICAL ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DATA EXTRACTION; EMERGENCY WARD; FEMALE; GASTROINTESTINAL INFECTION; HEALTH CARE POLICY; HEALTH STATUS; HUMAN; INTENSIVE CARE UNIT; INTERMETHOD COMPARISON; INTERVENTION STUDY; INTRAVENOUS CATHETER; LENGTH OF STAY; MALE; MEDICAL RECORD REVIEW; MORTALITY; OXYGEN SATURATION; PNEUMONIA; PRACTICE GUIDELINE; RETROSPECTIVE STUDY; SEPSIS; SEPTIC SHOCK; SKIN INFECTION; SOFT TISSUE INFECTION; TREATMENT OUTCOME; UROSEPSIS; AGED; CASE CONTROL STUDY; CHI SQUARE DISTRIBUTION; CLINICAL PROTOCOL; EMERGENCY HEALTH SERVICE; HOSPITAL ADMISSION; HOSPITALIZATION; METHODOLOGY; MIDDLE AGED; ORGANIZATION AND MANAGEMENT; RESUSCITATION; RISK FACTOR;

AGED; BRITISH COLUMBIA; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CLINICAL PROTOCOLS; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PATIENT ADMISSION; RESUSCITATION; RETROSPECTIVE STUDIES; RISK FACTORS; SEPSIS; SEVERITY OF ILLNESS INDEX;

EID: 79952196635     PISSN: 14818035     EISSN: 14818035     Source Type: Journal    
DOI: 10.1017/S1481803500012562     Document Type: Article

References (17)

1. Nguyen HB, Rivers EP, Abrahamian FM, et al. Severe sepsis and septic shock: review of the literature and emergency department management guidelines. Ann Emerg Med 2006; 48:28-54.
2. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77.
3. Trzeciak S, Dellinger RP, Abate NL, et al. Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. Chest 2006;129:225-32. (Pubitemid 43289838)
4. Jones AE, Foche A, Horton JM, et al. Prospective external validation of the clinical effectiveness of an emergency department-based early goal-directed therapy protocol for severe sepsis and septic shock. Chest 2007;132:425-32. (Pubitemid 47282372)
5. Shapiro NI, Howell MD, Talmor D, et al. Implementation and outcomes of the Multiple Urgent Sepsis Therapies (MUST) protocol. Crit Care Med 2006;34:1025-32.
6. Gao F, Melody T, Daniels DF, et al. The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study. Crit Care 2005;9:R764-70.
7. Kortgen A, Niederprum P, Bauer M. Implementation of an evidence-based "standard operating procedure" and outcome in septic shock. Crit Care Med 2006;34:943-9.
8. Micek ST, Roubinian N, Heuring T, et al. Before-after study of a standardized hospital order set for the management of septic shock. Crit Care Med 2006;34:2707-13. (Pubitemid 44610934)
9. Sebat F, Johnson D, Musthafa AA, et al. A multidisciplinary community hospital program for early and rapid resuscitation of shock in nontrauma patients. Chest 2005;127:1729-43. (Pubitemid 46218802)
10. Nguyen HB, Corbett SW, Steele R, et al. Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality. Crit Care Med 2007;35:1105-12. (Pubitemid 46598962)
11. Rogove J, Pyle K. Collaboration for instituting the surviving sepsis campaign in a community hospital. Crit Care Med 2005;33(12 Suppl):A28.
12. Verceles, A, Schwarcz, RM, Garcha, P, et al. Factors influencing survival in patients with severe sepsis treated with a therapeutic pathway. Chest 2006;130:223S.
13. Stenstrom RJ, Hollohan K, Nebre R. Impact of a sepsis protocol for the management of patients with severe sepsis and septic shock in the emergency department. CJEM 2006;8:S16.
14. Otero RM, Nguyen HB, Huang DT, et al. Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary findings. Chest 2006;130:1579-95. (Pubitemid 44786757)
15. Beveridge R, Clarke B, Janes L, et al. Canadian Emergency Department Triage and Acuity Scale: implementation guidelines. CJEM 1999;1(Suppl3).
16. Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006;34:1589-96. (Pubitemid 43810035)
17. Angus D, Kellum J, Yealy D. Protocolized care for early septic shock (ProCESS). Bethesda (MD): National Library of Medicine; 2009. Available: http://clinicaltrials.gov/ct2/show /NCT00510835. ClinicalTrials.gov identifier: NCT00510835.