-
1
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral effcacy
-
Heise, C, Hermiston, T, Johnson, L, Brooks, G, Sampson-Johannes, A, Williams, A et al. (2000). An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral effcacy. Nat Med 6: 1134-1139.
-
(2000)
Nat Med
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, T.2
Johnson, L.3
Brooks, G.4
Sampson-Johannes, A.5
Williams, A.6
-
2
-
-
31544471784
-
Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: Comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin
-
DOI 10.1158/0008-5472.CAN-05-2691
-
Lockley, M, Fernandez, M, Wang, Y, Li, NF, Conroy, S, Lemoine, N et al. (2006). Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin. Cancer Res 66: 989-998. (Pubitemid 43165967)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 989-998
-
-
Lockley, M.1
Fernandez, M.2
Wang, Y.3
Li, N.F.4
Conroy, S.5
Lemoine, N.6
McNeish, I.7
-
3
-
-
43749104658
-
Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer
-
DOI 10.1038/sj.onc.1210977, PII 1210977
-
Baird, SK, Aerts, JL, Eddaoudi, A, Lockley, M, Lemoine, NR and McNeish, IA (2008). Oncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancer. Oncogene 27: 3081-3090. (Pubitemid 351693172)
-
(2008)
Oncogene
, vol.27
, Issue.22
, pp. 3081-3090
-
-
Baird, S.K.1
Aerts, J.L.2
Eddaoudi, A.3
Lockley, M.4
Lemoine, N.R.5
McNeish, I.A.6
-
4
-
-
79251593305
-
A phase i study of the infectivity enhanced CRAd Ad5-Δ24RGD for recurrent gynecologic cancer
-
Abstr 5107
-
Curiel, DT, Preuss, M, Wang, M, Kimball, KJ, Barnes, MN, Wan, W et al. (2010). A phase I study of the infectivity enhanced CRAd Ad5-Δ24RGD for recurrent gynecologic cancer. J Clin Oncol 28 [Abstr 5107].
-
(2010)
J Clin Oncol
, vol.28
-
-
Curiel, D.T.1
Preuss, M.2
Wang, M.3
Kimball, K.J.4
Barnes, M.N.5
Wan, W.6
-
5
-
-
0036828125
-
Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): Phase II viral, immunologic, and clinical endpoints
-
Reid, T, Galanis, E, Abbruzzese, J, Sze, D, Wein, LM, Andrews, J et al. (2002). Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. Cancer Res 62: 6070-6079. (Pubitemid 35244455)
-
(2002)
Cancer Research
, vol.62
, Issue.21
, pp. 6070-6079
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
Sze, D.4
Wein, L.M.5
Andrews, J.6
Randlev, B.7
Heise, C.8
Uprichard, M.9
Hatfield, M.10
Rome, L.11
Rubin, J.12
Kirn, D.13
-
6
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
DOI 10.1016/j.ymgme.2003.08.016
-
Raper, SE, Chirmule, N, Lee, FS, Wivel, NA, Bagg, A, Gao, GP et al. (2003). Fatal systemic infammatory response syndrome in a ornithine transcarbamylase defcient patient following adenoviral gene transfer. Mol Genet Metab 80: 148-158. (Pubitemid 37272241)
-
(2003)
Molecular Genetics and Metabolism
, vol.80
, Issue.1-2
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
Wivel, N.A.4
Bagg, A.5
Gao, G.-P.6
Wilson, J.M.7
Batshaw, M.L.8
-
7
-
-
0038069517
-
The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors
-
DOI 10.1089/104303403321618146
-
Liu, Q, Zaiss, AK, Colarusso, P, Patel, K, Haljan, G, Wickham, TJ et al. (2003). The role of capsid-endothelial interactions in the innate immune response to adenovirus vectors. Hum Gene Ther 14: 627-643. (Pubitemid 36543435)
-
(2003)
Human Gene Therapy
, vol.14
, Issue.7
, pp. 627-643
-
-
Liu, Q.1
Zaiss, A.K.2
Colarusso, P.3
Patel, K.4
Haljan, G.5
Wickham, T.J.6
Muruve, D.A.7
-
8
-
-
68249158537
-
Virus binding to a plasma membrane receptor triggers interleukin-1 α-mediated proinfammatory macrophage response in vivo
-
Di Paolo, NC, Miao, EA, Iwakura, Y, Murali-Krishna, K, Aderem, A, Flavell, RA et al. (2009). Virus binding to a plasma membrane receptor triggers interleukin-1 α-mediated proinfammatory macrophage response in vivo. Immunity 31: 110-121.
-
(2009)
Immunity
, vol.31
, pp. 110-121
-
-
Di Paolo, N.C.1
Miao, E.A.2
Iwakura, Y.3
Murali-Krishna, K.4
Aderem, A.5
Flavell, R.A.6
-
9
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
DOI 10.1038/nature06664, PII NATURE06664
-
Muruve, DA, Pétrilli, V, Zaiss, AK, White, LR, Clark, SA, Ross, PJ et al. (2008). The infammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452: 103-107. (Pubitemid 351355095)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
Parks, R.J.7
Tschopp, J.8
-
10
-
-
0036202249
-
Adenovirus vector-induced inflammation: Capsid-dependent induction of the C-C chemokine RANTES requires NF-κB
-
DOI 10.1089/10430340252792503
-
Bowen, G P, Borgland, SL, Lam, M, Libermann, TA, Wong, NC and Muruve, DA (2002). Adenovirus vector-induced infammation: capsid-dependent induction of the C-C chemokine RANTES requires NF-κB. Hum Gene Ther 13: 367-379. (Pubitemid 34251502)
-
(2002)
Human Gene Therapy
, vol.13
, Issue.3
, pp. 367-379
-
-
Bowen, G.P.1
Borgland, S.L.2
Lam, M.3
Libermann, T.A.4
Wong, N.C.W.5
Muruve, D.A.6
-
11
-
-
0036145860
-
Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10
-
DOI 10.1128/JVI.76.4.1559-1568.2002
-
Tibbles, LA, Spurrell, JC, Bowen, GP, Liu, Q, Lam, M, Zaiss, AK et al. (2002). Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10. J Virol 76: 1559-1568. (Pubitemid 34094602)
-
(2002)
Journal of Virology
, vol.76
, Issue.4
, pp. 1559-1568
-
-
Tibbles, L.A.1
Spurrell, J.C.L.2
Bowen, G.P.3
Liu, Q.4
Lam, M.5
Zaiss, A.K.6
Robbins, S.M.7
Hollenberg, M.D.8
Wickham, T.J.9
Muruve, D.A.10
-
12
-
-
23744485808
-
Inhibition of NF-κB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy
-
DOI 10.1038/sj.gt.3302510
-
Palmer, DH, Chen, MJ, Searle, PF, Kerr, DJ and Young, LS (2005). Inhibition of NF-κB enhances the cytotoxicity of virus-directed enzyme prodrug therapy and oncolytic adenovirus cancer gene therapy. Gene Ther 12: 1187-1197. (Pubitemid 41136313)
-
(2005)
Gene Therapy
, vol.12
, Issue.15
, pp. 1187-1197
-
-
Palmer, D.H.1
Chen, M.-J.2
Searle, P.F.3
Kerr, D.J.4
Young, L.S.5
-
13
-
-
0034722892
-
Replication-selective oncolytic adenoviruses: Virotherapy aimed at genetic targets in cancer
-
DOI 10.1038/sj.onc.1204094
-
Kirn, D (2000). Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer. Oncogene 19: 6660-6669. (Pubitemid 32197705)
-
(2000)
Oncogene
, vol.19
, Issue.56
, pp. 6660-6669
-
-
Kirn, D.1
-
14
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
DOI 10.1016/S0092-8674(01)00237-9
-
Locksley, RM, Killeen, N and Lenardo, MJ (2001). The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104: 487-501. (Pubitemid 32201945)
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
15
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
DOI 10.1016/S0092-8674(03)00521-X
-
Micheau, O and Tschopp, J (2003). Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114: 181-190. (Pubitemid 36936912)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
16
-
-
67349162130
-
Tumour necrosis factor and cancer
-
Balkwill, F (2009). Tumour necrosis factor and cancer. Nat Rev Cancer 9: 361-371.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 361-371
-
-
Balkwill, F.1
-
17
-
-
0032983865
-
Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis
-
DOI 10.1038/10552
-
Moore, RJ, Owens, DM, Stamp, G, Arnott, C, Burke, F, East, N et al. (1999). Mice defcient in tumor necrosis factor-α are resistant to skin carcinogenesis. Nat Med 5: 828-831. (Pubitemid 29318619)
-
(1999)
Nature Medicine
, vol.5
, Issue.7
, pp. 828-831
-
-
Moore, R.J.1
Owens, D.M.2
Stamp, G.3
Arnott, C.4
Burke, F.5
East, N.6
Holdsworth, H.7
Turner, L.8
Rollins, B.9
Pasparakis, M.10
Kollias, G.11
Balkwill, F.12
-
18
-
-
0037130471
-
Tumour necrosis factor-α mediates tumour promotion via a PKCα- and AP-1-dependent pathway
-
DOI 10.1038/sj.onc.1205588
-
Arnott, CH, Scott, KA, Moore, RJ, Hewer, A, Phillips, DH, Parker, P et al. (2002). Tumour necrosis factor-α mediates tumour promotion via a PKC α- and AP-1-dependent pathway. Oncogene 21: 4728-4738. (Pubitemid 34879448)
-
(2002)
Oncogene
, vol.21
, Issue.31
, pp. 4728-4738
-
-
Arnott, C.H.1
Scott, K.A.2
Moore, R.J.3
Hewer, A.4
Phillips, D.H.5
Parker, P.6
Balkwill, F.R.7
Owens, D.M.8
-
19
-
-
0027163955
-
Tumor necrosis factor and its receptors in human ovarian cancer: Potential role in disease progression
-
Naylor, MS, Stamp, GW, Foulkes, WD, Eccles, D and Balkwill, FR (1993). Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression. J Clin Invest 91: 2194-2206. (Pubitemid 23141496)
-
(1993)
Journal of Clinical Investigation
, vol.91
, Issue.5
, pp. 2194-2206
-
-
Naylor, M.S.1
Stamp, G.W.H.2
Foulkes, W.D.3
Eccles, D.4
Balkwill, F.R.5
-
20
-
-
33846682591
-
The inflammatory cytokine tumor necrosis factor-α generates an autocrine tumor-promoting network in epithelial ovarian cancer cells
-
DOI 10.1158/0008-5472.CAN-06-2941
-
Kulbe, H, Thompson, R, Wilson, JL, Robinson, S, Hagemann, T, Fatah, R et al. (2007). The infammatory cytokine tumor necrosis factor-α generates an autocrine tumor-promoting network in epithelial ovarian cancer cells. Cancer Res 67: 585-592. (Pubitemid 46192196)
-
(2007)
Cancer Research
, vol.67
, Issue.2
, pp. 585-592
-
-
Kulbe, H.1
Thompson, R.2
Wilson, J.L.3
Robinson, S.4
Hagemann, T.5
Fatah, R.6
Gould, D.7
Ayhan, A.8
Balkwill, F.9
-
21
-
-
24944554981
-
Study of etanercept, a tumor necrosis factor-α inhibitor, in recurrent ovarian cancer
-
Madhusudan, S, Muthuramalingam, SR, Braybrooke, JP, Wilner, S, Kaur, K, Han, C et al. (2005). Study of etanercept, a tumor necrosis factor-α inhibitor, in recurrent ovarian cancer. J Clin Oncol 23: 5950-5959.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5950-5959
-
-
Madhusudan, S.1
Muthuramalingam, S.R.2
Braybrooke, J.P.3
Wilner, S.4
Kaur, K.5
Han, C.6
-
22
-
-
46249120755
-
A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer
-
DOI 10.1093/annonc/mdn054
-
Brown, ER, Charles, KA, Hoare, SA, Rye, RL, Jodrell, DI, Aird, RE et al. (2008). A clinical study assessing the tolerability and biological effects of infiximab, a TNF-α inhibitor, in patients with advanced cancer. Ann Oncol 19: 1340-1346. (Pubitemid 351911969)
-
(2008)
Annals of Oncology
, vol.19
, Issue.7
, pp. 1340-1346
-
-
Brown, E.R.1
Charles, K.A.2
Hoare, S.A.3
Rye, R.L.4
Jodrell, D.I.5
Aird, R.E.6
Vora, R.7
Prabhakar, U.8
Nakada, M.9
Corringham, R.E.10
Dewitte, M.11
Sturgeon, C.12
Propper, D.13
Balkwill, F.R.14
Smyth, J.F.15
-
23
-
-
0027409399
-
Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A
-
Yu, D, Wolf, JK, Scanlon, M, Price, JE and Hung, MC (1993). Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A. Cancer Res 53: 891-898. (Pubitemid 23077880)
-
(1993)
Cancer Research
, vol.53
, Issue.4
, pp. 891-898
-
-
Yu, D.1
Wolf, J.K.2
Scanlon, M.3
Price, J.E.4
Hung, M.-C.5
-
24
-
-
33749467859
-
18F] fluorothymidine positron emission tomography imaging
-
DOI 10.1158/0008-5472.CAN-06-1539
-
Leyton, J, Lockley, M, Aerts, JL, Baird, SK, Aboagye, EO, Lemoine, NR et al. (2006). Quantifying the activity of adenoviral E1A CR2 deletion mutants using renilla luciferase bioluminescence and 3'-deoxy-3'-[18F]fuorothymidine positron emission tomography imaging. Cancer Res 66: 9178-9185. (Pubitemid 44521138)
-
(2006)
Cancer Research
, vol.66
, Issue.18
, pp. 9178-9185
-
-
Leyton, J.1
Lockley, M.2
Aerts, J.L.3
Baird, S.K.4
Aboagye, E.O.5
Lemoine, N.R.6
McNeish, I.A.7
-
25
-
-
78149466754
-
Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer
-
epub ahead of print
-
Ingemarsdotter, CK, Baird, SK, Connell, CM, Oberg, D, Hallden, G, and McNeish, IA (2010). Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer. Oncogene (epub ahead of print
-
(2010)
Oncogene
-
-
Ingemarsdotter, C.K.1
Baird, S.K.2
Connell, C.M.3
Oberg, D.4
Hallden, G.5
McNeish, I.A.6
-
26
-
-
54049155149
-
C-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation
-
Varfolomeev, E, Goncharov, T, Fedorova, AV, Dynek, JN, Zobel, K, Deshayes, K et al. (2008). c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation. J Biol Chem 283: 24295-24299.
-
(2008)
J Biol Chem
, vol.283
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
Dynek, J.N.4
Zobel, K.5
Deshayes, K.6
-
27
-
-
36048999753
-
IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
-
DOI 10.1016/j.cell.2007.10.030, PII S0092867407013487
-
Varfolomeev, E, Blankenship, JW, Wayson, SM, Fedorova, AV, Kayagaki, N, Garg, P et al. (2007). IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis. Cell 131: 669-681. (Pubitemid 350087204)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
Zobel, K.7
Dynek, J.N.8
Elliott, L.O.9
Wallweber, H.J.A.10
Flygare, J.A.11
Fairbrother, W.J.12
Deshayes, K.13
Dixit, V.M.14
Vucic, D.15
-
28
-
-
36148954336
-
IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis
-
DOI 10.1016/j.cell.2007.10.037, PII S0092867407013578
-
Vince, JE, Wong, WW, Khan, N, Feltham, R, Chau, D, Ahmed, AU et al. (2007). IAP antagonists target cIAP1 to induce TNFα-dependent apoptosis. Cell 131: 682-693. (Pubitemid 350103599)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.-L.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
Benetatos, C.A.7
Chunduru, S.K.8
Condon, S.M.9
McKinlay, M.10
Brink, R.11
Leverkus, M.12
Tergaonkar, V.13
Schneider, P.14
Callus, B.A.15
Koentgen, F.16
Vaux, D.L.17
Silke, J.18
-
29
-
-
47549097367
-
TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFα
-
DOI 10.1083/jcb.200801010
-
Vince, JE, Chau, D, Callus, B, Wong, WW, Hawkins, CJ, Schneider, P et al. (2008). TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFα. J Cell Biol 182: 171-184. (Pubitemid 352008630)
-
(2008)
Journal of Cell Biology
, vol.182
, Issue.1
, pp. 171-184
-
-
Vince, J.E.1
Chau, D.2
Callus, B.3
Wong, W.W.-L.4
Hawkins, C.J.5
Schneider, P.6
McKinlay, M.7
Benetatos, C.A.8
Condon, S.M.9
Chunduru, S.K.10
Yeoh, G.11
Brink, R.12
Vaux, D.L.13
Silke, J.14
-
30
-
-
16244377737
-
Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo
-
DOI 10.1128/MCB.25.8.3348-3356.2005
-
Conze, DB, Albert, L, Ferrick, DA, Goeddel, DV, Yeh, WC, Mak, T et al. (2005). Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo. Mol Cell Biol 25: 3348-3356. (Pubitemid 40464334)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.8
, pp. 3348-3356
-
-
Conze, D.B.1
Albert, L.2
Ferrick, D.A.3
Goeddel, D.V.4
Yeh, W.-C.5
Mak, T.6
Ashwell, J.D.7
-
31
-
-
33750682048
-
Interaction of adenovirus type 5 fiber with the coxsackievirus and adenovirus receptor activates inflammatory response in human respiratory cells
-
DOI 10.1128/JVI.00721-06
-
Tamanini, A, Nicolis, E, Bonizzato, A, Bezzerri, V, Melotti, P, Assael, BM et al. (2006). Interaction of adenovirus type 5 fber with the coxsackievirus and adenovirus receptor activates infammatory response in human respiratory cells. J Virol 80: 11241-11254. (Pubitemid 44706564)
-
(2006)
Journal of Virology
, vol.80
, Issue.22
, pp. 11241-11254
-
-
Tamanini, A.1
Nicolis, E.2
Bonizzato, A.3
Bezzerri, V.4
Melotti, P.5
Assael, B.M.6
Cabrini, G.7
-
32
-
-
58149154996
-
Mechanisms and pathologic signifcances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease
-
Nishimoto, N, Terao, K, Mima, T, Nakahara, H, Takagi, N and Kakehi, T (2008). Mechanisms and pathologic signifcances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease. Blood 112: 3959-3964.
-
(2008)
Blood
, vol.112
, pp. 3959-3964
-
-
Nishimoto, N.1
Terao, K.2
Mima, T.3
Nakahara, H.4
Takagi, N.5
Kakehi, T.6
-
33
-
-
2342625392
-
Analysis of Adenovirus Sequestration in the Liver, Transduction of Hepatic Cells, and Innate Toxicity after Injection of Fiber-Modified Vectors
-
DOI 10.1128/JVI.78.10.5368-5381.2004
-
Shayakhmetov, DM, Li, ZY, Ni, S and Lieber, A (2004). Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fber-modifed vectors. J Virol 78: 5368-5381. (Pubitemid 38581487)
-
(2004)
Journal of Virology
, vol.78
, Issue.10
, pp. 5368-5381
-
-
Shayakhmetov, D.M.1
Li, Z.-Y.2
Ni, S.3
Lieber, A.4
-
34
-
-
18944396179
-
Adenovirus binding to blood factors results in liver cell infection and hepatotoxicity
-
DOI 10.1128/JVI.79.12.7478-7491.2005
-
Shayakhmetov, DM, Gaggar, A, Ni, S, Li, ZY and Lieber, A (2005). Adenovirus binding to blood factors results in liver cell infection and hepatotoxicity. J Virol 79: 7478-7491. (Pubitemid 40756784)
-
(2005)
Journal of Virology
, vol.79
, Issue.12
, pp. 7478-7491
-
-
Shayakhmetov, D.M.1
Gaggar, A.2
Ni, S.3
Li, Z.-Y.4
Lieber, A.5
-
35
-
-
4544365537
-
Acute hepatotoxicity of oncolytic adenoviruses in mouse models is associated with expression of wild-type E1a and induction of TNF-α
-
DOI 10.1016/j.virol.2004.06.043, PII S0042682204004507
-
Engler, H, Machemer, T, Philopena, J, Wen, SF, Quijano, E, Ramachandra, M et al. (2004). Acute hepatotoxicity of oncolytic adenoviruses in mouse models is associated with expression of wild-type E1a and induction of TNF-α. Virology 328: 52-61. (Pubitemid 39221912)
-
(2004)
Virology
, vol.328
, Issue.1
, pp. 52-61
-
-
Engler, H.1
Machemer, T.2
Philopena, J.3
Wen, S.-F.4
Quijano, E.5
Ramachandra, M.6
Tsai, V.7
Ralston, R.8
-
36
-
-
14844323968
-
XIAP inhibits caspase-3 and -7 using two binding sites: Evolutionary conserved mechanism of IAPs
-
DOI 10.1038/sj.emboj.7600544
-
Scott, FL, Denault, JB, Riedl, SJ, Shin, H, Renatus, M and Salvesen, GS (2005). XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs. EMBO J 24: 645-655. (Pubitemid 40343265)
-
(2005)
EMBO Journal
, vol.24
, Issue.3
, pp. 645-655
-
-
Scott, F.L.1
Denault, J.-B.2
Riedl, S.J.3
Shin, H.4
Renatus, M.5
Salvesen, G.S.6
-
37
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
-
DOI 10.1038/35065125
-
Srinivasula, SM, Hegde, R, Saleh, A, Datta, P, Shiozaki, E, Chai, J et al. (2001). A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature 410: 112-116. (Pubitemid 32225846)
-
(2001)
Nature
, vol.410
, Issue.6824
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
Lee, R.-A.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.10
Alnemri, E.S.11
-
38
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
DOI 10.1093/emboj/17.8.2215
-
Deveraux, QL, Roy, N, Stennicke, HR, Van Arsdale, T, Zhou, Q, Srinivasula, SM et al. (1998). IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J 17: 2215-2223. (Pubitemid 28171907)
-
(1998)
EMBO Journal
, vol.17
, Issue.8
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
Van Arsdale, T.4
Zhou, Q.5
Srinivasula, S.M.6
Alnemri, E.S.7
Salvesen, G.S.8
Reed, J.C.9
-
39
-
-
12344300349
-
IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
-
DOI 10.1038/ncb1204
-
Tenev, T, Zachariou, A, Wilson, R, Ditzel, M and Meier, P (2005). IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms. Nat Cell Biol 7: 70-77. (Pubitemid 40123385)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.1
, pp. 70-77
-
-
Tencho, T.1
Zachariou, A.2
Wilson, R.3
Ditzel, M.4
Meier, P.5
-
40
-
-
44949240664
-
CIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination
-
DOI 10.1016/j.molcel.2008.05.014, PII S1097276508003882
-
Bertrand, MJ, Milutinovic, S, Dickson, KM, Ho, WC, Boudreault, A, Durkin, J et al. (2008). cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 30: 689-700. (Pubitemid 351818251)
-
(2008)
Molecular Cell
, vol.30
, Issue.6
, pp. 689-700
-
-
Bertrand, M.J.M.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
41
-
-
67649794805
-
The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing
-
Choi, YE, Butterworth, M, Malladi, S, Duckett, CS, Cohen, GM and Bratton, SB (2009). The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing. J Biol Chem 284: 12772-12782.
-
(2009)
J Biol Chem
, vol.284
, pp. 12772-12782
-
-
Choi, Y.E.1
Butterworth, M.2
Malladi, S.3
Duckett, C.S.4
Cohen, G.M.5
Bratton, S.B.6
-
42
-
-
67650375869
-
Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication
-
Prestwich, RJ, Ilett, EJ, Errington, F, Diaz, RM, Steele, L P, Kottke, T et al. (2009). Immune-mediated antitumor activity of reovirus is required for therapy and is independent of direct viral oncolysis and replication. Clin Cancer Res 15: 4374-4381.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4374-4381
-
-
Prestwich, R.J.1
Ilett, E.J.2
Errington, F.3
Diaz, R.M.4
Steele, L.P.5
Kottke, T.6
-
43
-
-
35648936526
-
Tumor necrosis factor α as a new target for renal cell carcinoma: Two sequential phase II trials of infliximab at standard and high dose
-
DOI 10.1200/JCO.2007.11.2136
-
Harrison, ML, Obermueller, E, Maisey, NR, Hoare, S, Edmonds, K, Li, NF et al. (2007). Tumor necrosis factor α as a new target for renal cell carcinoma: two sequential phase II trials of infiximab at standard and high dose. J Clin Oncol 25: 4542-4549. (Pubitemid 350035310)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.29
, pp. 4542-4549
-
-
Harrison, M.L.1
Obermueller, E.2
Maisey, N.R.3
Hoare, S.4
Edmonds, K.5
Li, N.F.6
Chao, D.7
Hall, K.8
Lee, C.9
Timotheadou, E.10
Charles, K.11
Ahern, R.12
King, D.M.13
Eisen, T.14
Corringham, R.15
DeWitte, M.16
Balkwill, F.17
Gore, M.18
-
44
-
-
0035017144
-
Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells
-
DOI 10.1038/sj.cgt.7700305
-
McNeish, IA, Tenev, T, Bell, S, Marani, M, Vassaux, G and Lemoine, N (2001). Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells. Cancer Gene Ther 8: 308-319. (Pubitemid 32480068)
-
(2001)
Cancer Gene Therapy
, vol.8
, Issue.4
, pp. 308-319
-
-
McNeish, I.A.1
Tenev, T.2
Bell, S.3
Marani, M.4
Vassaux, G.5
Lemoine, N.6
-
45
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann, T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63. (Pubitemid 14203433)
-
(1983)
Journal of Immunological Methods
, vol.65
, Issue.1-2
, pp. 55-63
-
-
Mosmann, T.1
|