Role of CD4+CD25+ T cells in children with idiopathic thrombocytopenic purpura

Journal of Pediatric Hematology/Oncology

Volumn 33, Issue 2, 2011, Pages 81-85

  Aboul Fotoh, Laila El Morsi ^a   Raheem, Moustafa Mohamed Abdel ^a   El Deen, Mohammed Ahmed Bahaa ^a   Osman, Ashraf Mohammed Mohammed ^a  

^a Minia University   (Egypt)

Author keywords

CD4+CD 25+ T cells; children; idiopathic thrombocytopenic purpura

Indexed keywords

ARTICLE; BLOOD CELL COUNT; CD4+ CD25+ T LYMPHOCYTE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; COOMBS TEST; DISEASE COURSE; DISEASE SEVERITY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNE DYSREGULATION; IMMUNOPATHOGENESIS; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REMISSION; SCHOOL CHILD; THROMBOCYTE COUNT; IMMUNOLOGY;

CHILD; CHILD, PRESCHOOL; FEMALE; FLOW CYTOMETRY; HUMANS; MALE; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; T-LYMPHOCYTES, REGULATORY;

EID: 79952185498     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e3181f46b82     Document Type: Article

References (24)

1. + regulatory T cells in immunological tolerance to se (Pubitemid 41716771)
2. Gernsheimer T. Pathophysiology and thrombokinetics in autoimmune thrombocytopenia. Blood Rev. 2002;16:7-8. (Pubitemid 34293543)
3. Crow MK, DelGiudice-Asch G, Zehetbauer JB, et al. Autoantigen-specific T-cell proliferation induced by the ribosomal P2 protein in patients with systemic lupus erythematosus. J Clin Invest. 1994;94:345-352. (Pubitemid 24218110)
4. Ota K, Matsui M, Milford EL, et al. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature. 1990;346:183-187.
5. + T cells in patients with idiopathic thrombocytopenic purpura. Thromb Res. 2007;120:187-193. (Pubitemid 46754414)
6. 25 regulatory T-cells down-regulate co-stimulatory molecules on antigen presenting cells. Eur J Immunol. 2000;30:1538-1543. (Pubitemid 30342794)
7. Kuwana M, Ikeda Y. Helicobacter pylori and immune thrombocytopenic purpura: Unsolved questions and controversies. Int J Hematol. 2006;84:309-315. (Pubitemid 46606571)
8. Lanzkowsky P. Idiopathic (autoimmune) thrombocytopenic purpura. In: Lanzkowsky P, ed. Manual of pediatric hematology and oncology. 3rd ed. San Diego, San Francisco, New York, Boston: Academic Press; 2000:233-250.
9. Karpatkin S. Autoimmune (idiopathic) thrombocytopenic purpura. Lancet. 1997;349:1531-1536. (Pubitemid 27216374)
10. Wang S, Cai G, Lu Y. Clinical implication of serum sIL-2R levels in ovarian cancer. J Tongji med Univ. 1998;18: 126-128.
11. Baur CK, Dugue RE, Shankey TV. Clinical Flow Cytometry, Principles and Application. 14th ed. Baltimore: Williams and Wilkins; 1993:195.
12. Imbach P, Kühne T, Signer E. Historical aspects and present knowledge of idiopathic thrombocytopenic purpura. Br J Haematol. 2002;119:894-900. (Pubitemid 35463812)
13. + Treg cells in health and disease. Clin Exp Pharmacol Physiol. 2006;33:519-524.
14. Olsson B, Andersson PO, Jacobsson S, et al. T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura. Nat Med. 2003;9:1123-1124. (Pubitemid 37173694)
15. Sayeh E, Sterling K, Speck E, et al. IgG antiplatelet immunity is dependent on an early innate natural killer cell-derived interferon-gamma response that is regulated by CD8 +T cells. Blood. 2004;103:2705-2709. (Pubitemid 38393028)
16. Nehls M, Kyewski B, Messerle M, et al. Two genetically separable steps in the differentiation of thymic epithelium. Science. 1996;272:886-889. (Pubitemid 26154594)
17. + regulatory T cells and Transforming growth factor-beta 1 in childhood immune thrombocytopenic Purpura. Egypt J Immunol. 2006;13:173-187.
18. 25 regulatory T cells in idiopathic thrombocytopenic purpura. Eur J Haematol. 2007;78:139-143. (Pubitemid 46058876)
19. + regulatory T cells in patients with idiopathicthrombocytopenic purpura. Zhonghua Xue Ye Xue Za Zhi. 2007;28:184-188.
20. 25 regulatory T cells in human thymus. Nature. 2005;436:1181-1185. (Pubitemid 41232298)
21. + regulatory T cells: I. Phenotype and physiology. APMIS. 2004;112:629-641. (Pubitemid 40101148)
22. 25(+FoxP3(+)) regulatory T cells in autoimmune diseases. Nat Clin Pract Rheumatol. 2007;3:619-626. (Pubitemid 350031751)
23. 25 regulatory T cells in patients with chronic immune thrombocytopenic purpura. Blood. 2008;112:1325-1328.
24. + cells. Semin Immunol. 2006;18:78-88. (Pubitemid 43248735)